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David Ramirez
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COVID-19: drug targets and potential treatments
C Gil, T Ginex, I Maestro, V Nozal, L Barrado-Gil, MÁ Cuesta-Geijo, ...
Journal of medicinal chemistry 63 (21), 12359-12386, 2020
2972020
Is it reliable to take the molecular docking top scoring position as the best solution without considering available structural data?
D Ramírez, J Caballero
Molecules 23 (5), 1038, 2018
2082018
Is It Reliable to Use Common Molecular Docking Methods for Comparing the Binding Affinities of Enantiomer Pairs for Their Protein Target?
D Ramírez, J Caballero
International Journal of Molecular Sciences 17 (525), 2016
1062016
Origin and evolution of transporter substrate specificity within the NPF family
ME Jørgensen, D Xu, C Crocoll, HA Ernst, D Ramírez, MS Motawia, ...
Elife 6, e19466, 2017
642017
Kv1. 5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
AK Kiper, S Rinné, C Rolfes, D Ramírez, G Seebohm, MF Netter, ...
Pflügers Archiv-European Journal of Physiology 467 (5), 1081-1090, 2015
642015
Computational methods applied to rational drug design
D Ramírez
The Open Medicinal Chemistry Journal 10, 7, 2016
452016
Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels
D Ramírez, W Gonzalez, RA Fissore, I Carvacho
Marine drugs 15 (10), 313, 2017
432017
Novel alkylimidazolium ionic liquids as an antibacterial alternative to pathogens of the skin and soft tissue infections
O Forero Doria, R Castro, M Gutierrez, D Gonzalez Valenzuela, L Santos, ...
Molecules 23 (9), 2354, 2018
402018
CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
JR Almeida, M Lancellotti, AM Soares, LA Calderón, D Ramírez, ...
Toxicon 120, 147-158, 2016
372016
Novel N‐allyl/propargyl tetrahydroquinolines: Synthesis via Three‐component Cationic Imino Diels–Alder Reaction, Binding Prediction, and Evaluation as …
YA Rodríguez, M Gutiérrez, D Ramírez, J Alzate‐Morales, CC Bernal, ...
Chemical biology & drug design 88 (4), 498-510, 2016
362016
Computational studies of snake venom toxins
PG Ojeda, D Ramírez, J Alzate-Morales, J Caballero, Q Kaas, ...
Toxins 10 (1), 8, 2017
282017
HCN channels: new therapeutic targets for pain treatment
D Ramírez, R Zúñiga, G Concha, L Zúñiga
Molecules 23 (9), 2094, 2018
262018
The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
S Rinne, AK Kiper, KS Vowinkel, D Ramírez, M Schewe, M Bedoya, ...
Elife 8, e39476, 2019
252019
Side Fenestrations Provide an “anchor” for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels
D Ramírez, B Arévalo, G Martínez, S Rinné, FV Sepúlveda, N Decher, ...
Molecular Pharmaceutics 14 (7), 2197-2208, 2017
202017
Functional mutagenesis screens reveal the ‘cap structure’formation in disulfide-bridge free TASK channels
M Goldstein, S Rinné, AK Kiper, D Ramírez, MF Netter, D Bustos, ...
Scientific reports 6 (1), 1-13, 2016
202016
K2P channels in plants and animals
W González, B Valdebenito, J Caballero, G Riadi, J Riedelsberger, ...
Pflügers Archiv-European Journal of Physiology 467 (5), 1091-1104, 2015
202015
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis
E Rojas-Prats, L Martinez-Gonzalez, C Gonzalo-Consuegra, NF Liachko, ...
European Journal of Medicinal Chemistry 210, 112968, 2021
192021
Discovery of novel TASK-3 channel blockers using a pharmacophore-based virtual screening
D Ramírez, G Concha, B Arévalo, L Prent-Peñaloza, L Zúñiga, AK Kiper, ...
International journal of molecular sciences 20 (16), 4014, 2019
192019
The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa
L Novoa-Aponte, D Ramírez, JM Argüello
Journal of Biological Chemistry 294 (13), 4934-4945, 2019
192019
Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus …
LM Resende, JR Almeida, R Schezaro-Ramos, RCO Collaço, LR Simioni, ...
Toxicon 127, 22-36, 2017
172017
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