| Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein C Dong, K Beis, J Nesper, AL Brunkan-LaMontagne, BR Clarke, ... Nature 444 (7116), 226-229, 2006 | 426 | 2006 |
| Substrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems M Wacker, MF Feldman, N Callewaert, M Kowarik, BR Clarke, NL Pohl, ... Proceedings of the National Academy of Sciences 103 (18), 7088-7093, 2006 | 264 | 2006 |
| The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli RF Collins, K Beis, C Dong, CH Botting, C McDonnell, RC Ford, ... Proceedings of the National Academy of Sciences 104 (7), 2390-2395, 2007 | 177 | 2007 |
| Nonreducing terminal modifications determine the chain length of polymannose O antigens of Escherichia coli and couple chain termination to polymer export via an ATP-binding … BR Clarke, L Cuthbertson, C Whitfield Journal of Biological Chemistry 279 (34), 35709-35718, 2004 | 143 | 2004 |
| Identification of an ATP‐binding cassette transport system required for translocation of lipopolysaccharide O‐antigen side‐chains across the cytoplasmic membrane of Klebsiella … D Bronner, BR Clarke, C Whitfield Molecular microbiology 14 (3), 505-519, 1994 | 137 | 1994 |
| Expression of two structurally distinct D-galactan O antigens in the lipopolysaccharide of Klebsiella pneumoniae serotype O1 C Whitfield, JC Richards, MB Perry, BR Clarke, LL MacLean Journal of bacteriology 173 (4), 1420-1431, 1991 | 135 | 1991 |
| Regulation of the Escherichia coli K5 capsule gene cluster by transcription antitermination MP Stevens, BR Clarke, IS Roberts Molecular microbiology 24 (5), 1001-1012, 1997 | 124 | 1997 |
| Periplasmic protein-protein contacts in the inner membrane protein Wzc form a tetrameric complex required for the assembly of Escherichia coli group 1 capsules RF Collins, K Beis, BR Clarke, RC Ford, M Hulley, JH Naismith, ... Journal of Biological Chemistry 281 (4), 2144-2150, 2006 | 93 | 2006 |
| Role of Rfe and RfbF in the initiation of biosynthesis of D-galactan I, the lipopolysaccharide O antigen from Klebsiella pneumoniae serotype O1 BR Clarke, D Bronner, WJ Keenleyside, WB Severn, JC Richards, ... Journal of bacteriology 177 (19), 5411-5418, 1995 | 93 | 1995 |
| Molecular cloning of the rfb region of Klebsiella pneumoniae serotype O1: K20: the rfb gene cluster is responsible for synthesis of the D-galactan IO polysaccharide BR Clarke, C Whitfield Journal of bacteriology 174 (14), 4614-4621, 1992 | 92 | 1992 |
| A high-molecular-weight fraction of smooth lipopolysaccharide in Klebsiella serotype O1: K20 contains a unique O-antigen epitope and determines resistance to nonspecific serum … KL McCALLUM, G Schoenhals, D Laakso, B Clarke, C Whitfield Infection and immunity 57 (12), 3816-3822, 1989 | 77 | 1989 |
| A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide G Hagelueken, BR Clarke, H Huang, A Tuukkanen, I Danciu, DI Svergun, ... Nature structural & molecular biology 22 (1), 50-56, 2015 | 74 | 2015 |
| Cloning, expression, and purification of the K5 capsular polysaccharide lyase (KflA) from coliphage K5A: evidence for two distinct K5 lyase enzymes BR Clarke, F Esumeh, IS Roberts Journal of Bacteriology 182 (13), 3761-3766, 2000 | 72 | 2000 |
| Genetic Organization of the Escherichia coli K10 Capsule Gene Cluster: Identification and Characterization of Two Conserved Regions in Group III Capsule Gene … BR Clarke, R Pearce, IS Roberts Journal of bacteriology 181 (7), 2279-2285, 1999 | 64 | 1999 |
| Molecular basis for the structural diversity in serogroup O2-antigen polysaccharides in Klebsiella pneumoniae BR Clarke, OG Ovchinnikova, SD Kelly, ML Williamson, JE Butler, B Liu, ... Journal of Biological Chemistry 293 (13), 4666-4679, 2018 | 57 | 2018 |
| Lipopolysaccharide O antigen size distribution is determined by a chain extension complex of variable stoichiometry in Escherichia coli O9a JD King, S Berry, BR Clarke, RJ Morris, C Whitfield Proceedings of the National Academy of Sciences 111 (17), 6407-6412, 2014 | 56 | 2014 |
| Coordination of polymerization, chain termination, and export in assembly of the Escherichia coli lipopolysaccharide O9a antigen in an ATP-binding cassette transporter … BR Clarke, LK Greenfield, C Bouwman, C Whitfield Journal of Biological Chemistry 284 (44), 30662-30672, 2009 | 54 | 2009 |
| In vitro reconstruction of the chain termination reaction in biosynthesis of the Escherichia coli O9a O-polysaccharide: the chain-length regulator, WbdD, catalyzes the addition … BR Clarke, MR Richards, LK Greenfield, D Hou, TL Lowary, C Whitfield Journal of Biological Chemistry 286 (48), 41391-41401, 2011 | 48 | 2011 |
| Full-length, oligomeric structure of Wzz determined by cryoelectron microscopy reveals insights into membrane-bound states RF Collins, V Kargas, BR Clarke, CA Siebert, DK Clare, PJ Bond, ... Structure 25 (5), 806-815. e3, 2017 | 46 | 2017 |
| A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family BR Clarke, OG Ovchinnikova, RP Sweeney, ER Kamski-Hennekam, ... Nature chemical biology 16 (4), 450-457, 2020 | 42 | 2020 |
James (Jim) H Naismith ORCID 0000-...Head of the MPLS Division & Professor of Structural Biology, University of Oxford,Verified email at strubi.ox.ac.uk
