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Giuseppe Tosto
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New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
8692022
White matter hyperintensities are a core feature of Alzheimer's disease: evidence from the dominantly inherited Alzheimer network
S Lee, F Viqar, ME Zimmerman, A Narkhede, G Tosto, TLS Benzinger, ...
Annals of neurology 79 (6), 929-939, 2016
4942016
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ...
Molecular psychiatry 25 (8), 1859-1875, 2020
2352020
White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?
FA Provenzano, J Muraskin, G Tosto, A Narkhede, BT Wasserman, ...
JAMA neurology 70 (4), 455-461, 2013
2122013
Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease
JC Lambert, B Grenier-Boley, D Harold, D Zelenika, V Chouraki, ...
Molecular psychiatry 18 (4), 461-470, 2013
1462013
Genome-wide association studies in Alzheimer’s disease: a review
G Tosto, C Reitz
Current neurology and neuroscience reports 13, 1-7, 2013
1342013
Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms
C Cruchaga, JL Del-Aguila, B Saef, K Black, MV Fernandez, J Budde, ...
Alzheimer's & Dementia 14 (2), 205-214, 2018
1282018
Whole‐exome sequencing in 20,197 persons for rare variants in Alzheimer's disease
NS Raghavan, AM Brickman, H Andrews, JJ Manly, N Schupf, R Lantigua, ...
Annals of clinical and translational neurology 5 (7), 832-842, 2018
1162018
The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment
G Tosto, ME Zimmerman, JL Hamilton, OT Carmichael, AM Brickman, ...
Alzheimer's & Dementia 11 (12), 1510-1519, 2015
1122015
The effect of white matter hyperintensities on cognition is mediated by cortical atrophy
B Rizvi, A Narkhede, BS Last, M Budge, G Tosto, JJ Manly, N Schupf, ...
Neurobiology of aging 64, 25-32, 2018
1102018
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease
C Reitz, G Tosto, R Mayeux, JA Luchsinger, ...
PloS one 7 (12), e50354, 2012
1072012
Predicting aggressive decline in mild cognitive impairment: the importance of white matter hyperintensities
G Tosto, ME Zimmerman, OT Carmichael, AM Brickman, ...
JAMA neurology 71 (7), 872-877, 2014
1052014
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)
C Reitz, G Tosto, B Vardarajan, E Rogaeva, M Ghani, RS Rogers, ...
Translational psychiatry 3 (5), e256-e256, 2013
882013
White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment
VA Guzman, OT Carmichael, C Schwarz, G Tosto, ME Zimmerman, ...
Alzheimer's & Dementia 9 (5), S124-S131, 2013
742013
Polygenic risk scores in familial Alzheimer disease
G Tosto, TD Bird, D Tsuang, DA Bennett, BF Boeve, C Cruchaga, K Faber, ...
Neurology 88 (12), 1180-1186, 2017
722017
An MRI measure of degenerative and cerebrovascular pathology in Alzheimer disease
AM Brickman, G Tosto, J Gutierrez, H Andrews, Y Gu, A Narkhede, B Rizvi, ...
Neurology 91 (15), e1402-e1412, 2018
632018
Genetics of Alzheimer’s disease: the importance of polygenic and epistatic components
N Raghavan, G Tosto
Current neurology and neuroscience reports 17, 1-10, 2017
612017
White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease
S Lee, ME Zimmerman, A Narkhede, SE Nasrabady, G Tosto, IB Meier, ...
PLoS One 13 (5), e0195838, 2018
592018
F‐box/LRR‐repeat protein 7 is genetically associated with Alzheimer's disease
G Tosto, H Fu, BN Vardarajan, JH Lee, R Cheng, D Reyes‐Dumeyer, ...
Annals of clinical and translational neurology 2 (8), 810-820, 2015
582015
Familial Alzheimer's disease sustained by presenilin 2 mutations: Systematic review of literature and genotype–phenotype correlation
M Canevelli, P Piscopo, G Talarico, N Vanacore, A Blasimme, A Crestini, ...
Neuroscience & Biobehavioral Reviews 42, 170-179, 2014
582014
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