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Liem H. Nguyen, Ph.D.
Liem H. Nguyen, Ph.D.
UT Southwestern Medical Center, Tulane School of Medicine
Bestätigte E-Mail-Adresse bei tulane.edu
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Lin28 enhances tissue repair by reprogramming cellular metabolism
N Shyh-Chang, H Zhu, TY De Soysa, G Shinoda, MT Seligson, ...
Cell 155 (4), 778-792, 2013
3712013
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models
LH Nguyen, DA Robinton, MT Seligson, L Wu, L Li, D Rakheja, ...
Cancer cell 26 (2), 248-261, 2014
2192014
Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer
X Sun, SC Wang, Y Wei, X Luo, Y Jia, L Li, P Gopal, M Zhu, I Nassour, ...
Cancer cell 32 (5), 574-589. e6, 2017
1982017
The polyploid state plays a tumor-suppressive role in the liver
S Zhang, K Zhou, X Luo, L Li, HC Tu, A Sehgal, LH Nguyen, Y Zhang, ...
Developmental cell 44 (4), 447-459. e5, 2018
1752018
Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
K Zhou, LH Nguyen, JB Miller, Y Yan, P Kos, H Xiong, L Li, J Hao, ...
Proceedings of the National Academy of Sciences 113 (3), 520-525, 2016
1482016
Suppression of the SWI/SNF component Arid1a promotes mammalian regeneration
X Sun, JC Chuang, M Kanchwala, L Wu, C Celen, L Li, H Liang, S Zhang, ...
Cell stem cell 18 (4), 456-466, 2016
1452016
Knockdown of anillin actin binding protein blocks cytokinesis in hepatocytes and reduces liver tumor development in mice without affecting regeneration
S Zhang, LH Nguyen, K Zhou, HC Tu, A Sehgal, I Nassour, L Li, P Gopal, ...
Gastroenterology 154 (5), 1421-1434, 2018
1082018
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment
C Celen, JC Chuang, X Luo, N Nijem, AK Walker, F Chen, S Zhang, ...
Elife 6, e25730, 2017
1032017
SWI/SNF component ARID1A restrains pancreatic neoplasia formation
SC Wang, I Nassour, S Xiao, S Zhang, X Luo, J Lee, L Li, X Sun, ...
Gut 68 (7), 1259-1270, 2019
782019
Precise let-7 expression levels balance organ regeneration against tumor suppression
L Wu, LH Nguyen, K Zhou, TY de Soysa, L Li, JB Miller, J Tian, J Locker, ...
Elife 4, e09431, 2015
642015
Hepatic arterial infusion of low-density lipoprotein docosahexaenoic acid nanoparticles selectively disrupts redox balance in hepatoma cells and reduces growth of orthotopic …
X Wen, L Reynolds, RS Mulik, SY Kim, T Van Treuren, LH Nguyen, H Zhu, ...
Gastroenterology 150 (2), 488-498, 2016
532016
Lin28 and let-7 in cell metabolism and cancer
LH Nguyen, H Zhu
Translational Pediatrics 4 (1), 4, 2015
452015
Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer
X Sun, SC Wang, Y Wei, X Luo, Y Jia, L Li, P Gopal, M Zhu, I Nassour, ...
Cancer Cell 33 (1), 151-152, 2018
342018
A small molecule screen to identify regulators of let-7 targets
J Cinkornpumin, M Roos, L Nguyen, X Liu, X Gaeta, S Lin, DN Chan, ...
Scientific reports 7 (1), 15973, 2017
232017
SGN-CD228A: A novel humanized anti-CD228 antibody-drug conjugate for the treatment of solid tumors
SL Sandall, M Mason, D Olson, R Mazahreh, T Pires, D Sahetya, ...
Cancer Research 79 (13_Supplement), 2688-2688, 2019
52019
Lin28 enhances tissue repair by reprogramming cellular metabolism
MT Seligson, KM Tsanov, L Nguyen, JM Asara, LC Cantley, GQ Daley
Cell 155, 778-792, 2013
52013
SGN-EGFRd2 binding and activity are agnostic to common EGFR extracellular resistance mutations acquired in response to anti-EGFR targeted antibody therapies
L Nguyen, CS Wong, S Wo, B Grogan, D Diolaiti, MC Palanca-Wessels, ...
Cancer Research 84 (6_Supplement), 2355-2355, 2024
2024
Knockdown of anillin actin binding protein blocks cytokinesis in hepatocytes and reduces liver tumor development in mice without affecting regeneration (vol 154, pg 1421, 2018)
S Zhang, LH Nguyen, K Zhou
GASTROENTEROLOGY 155 (6), 2027-2027, 2018
2018
Abstract B10: The polyploid state plays a tumor-suppressive role in the liver
S Zhang, K Zhou, X Luo, L Li, L Nguyen, Y Zhang, B Tarlow, D Siegwart, ...
Cancer Research 78 (10_Supplement), B10-B10, 2018
2018
The Functional Roles of the Lin28/let-7 Axis in Tissue Regeneration and Cancer
LH Nguyen
2017
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