| Stereodivergent protein engineering of a lipase to access all possible stereoisomers of chiral esters with two stereocenters J Xu, Y Cen, W Singh, J Fan, L Wu, X Lin, J Zhou, M Huang, MT Reetz, ... Journal of the American Chemical Society 141 (19), 7934-7945, 2019 | 116 | 2019 |
| Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution Y Cen, W Singh, M Arkin, TS Moody, M Huang, J Zhou, Q Wu, MT Reetz Nature communications 10 (1), 3198, 2019 | 76 | 2019 |
| Conformational dynamics, ligand binding and effects of mutations in NirE an S-adenosyl-L-methionine dependent methyltransferase W Singh, TG Karabencheva-Christova, GW Black, J Ainsley, L Dover, ... Scientific reports 6 (1), 20107, 2016 | 27 | 2016 |
| The complex structure of bile salt hydrolase from Lactobacillus salivarius reveals the structural basis of substrate specificity F Xu, XJ Hu, W Singh, W Geng, IG Tikhonova, J Lin Scientific Reports 9 (1), 12438, 2019 | 24 | 2019 |
| Importance of the linker region in matrix metalloproteinase-1 domain interactions W Singh, GB Fields, CZ Christov, TG Karabencheva-Christova RSC advances 6 (28), 23223-23232, 2016 | 18 | 2016 |
| Effects of mutations on structure–function relationships of matrix metalloproteinase-1 W Singh, GB Fields, CZ Christov, TG Karabencheva-Christova International journal of molecular sciences 17 (10), 1727, 2016 | 17 | 2016 |
| Taming tris (bipyridine) ruthenium (II) and its reactions in water by capture/release with shape-switchable symmetry-matched cyclophanes C Yao, H Lin, B Daly, Y Xu, W Singh, HQN Gunaratne, WR Browne, ... Journal of the American Chemical Society 144 (11), 4977-4988, 2022 | 12 | 2022 |
| Mechanism of phosphatidylglycerol activation catalyzed by prolipoprotein diacylglyceryl transferase W Singh, M Bilal, J McClory, D Dourado, D Quinn, TS Moody, I Sutcliffe, ... The Journal of Physical Chemistry B 123 (33), 7092-7102, 2019 | 12 | 2019 |
| Reaction mechanism of isopentenyl phosphate kinase: a QM/MM study J McClory, DJ Timson, W Singh, J Zhang, M Huang The Journal of Physical Chemistry B 121 (49), 11062-11071, 2017 | 12 | 2017 |
| Regio-and stereoselectivity in the CYP450 BM3-catalyzed hydroxylation of complex terpenoids: a QM/MM study C Hui, W Singh, D Quinn, C Li, TS Moody, M Huang Physical Chemistry Chemical Physics 22 (38), 21696-21706, 2020 | 10 | 2020 |
| Reaction mechanism of histone demethylation in αKG-dependent non-heme iron enzymes W Singh, D Quinn, TS Moody, M Huang The Journal of Physical Chemistry B 123 (37), 7801-7811, 2019 | 9 | 2019 |
| Conformational flexibility influences structure–function relationships in tyrosyl protein sulfotransferase-2 W Singh, TG Karabencheva-Christova, GW Black, O Sparagano, ... RSC advances 6 (14), 11344-11352, 2016 | 9 | 2016 |
| Computer-Informed Engineering: A New Class I Sesquiterpene Synthase JeSTS4 for the Synthesis of an Unusual C10-(S)-Bicyclogermacrene X Yan, J Zhou, J Ge, W Li, D Liang, W Singh, G Black, S Nie, J Liu, M Sun, ... ACS Catalysis 12 (7), 4037-4045, 2022 | 7 | 2022 |
| Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis S Olatunji, K Bowen, CY Huang, D Weichert, W Singh, IG Tikhonova, ... Nature Communications 12 (1), 4254, 2021 | 7 | 2021 |
| Single-Site Mutation Induces Water-Mediated Promiscuity in Lignin Breaking Cytochrome P450GcoA W Singh, SFG Santos, P James, GW Black, M Huang, KD Dubey ACS omega 7 (24), 21109-21118, 2022 | 5 | 2022 |
| Dimerization and ligand binding in tyrosylprotein sulfotransferase-2 are influenced by molecular motions W Singh, TG Karabencheva-Christova, O Sparagano, GW Black, ... RSC advances 6 (22), 18542-18548, 2016 | 4 | 2016 |
| Simulations reveal the key role of Arg15 in the promiscuous activity in the HisA enzyme KD Dubey, W Singh Organic & Biomolecular Chemistry 19 (48), 10652-10661, 2021 | 3 | 2021 |
| The substrate specificity in the O-demethylation of 4-alkylguaiacols by cytochrome P450 AgcA P450 SFG Santos, RR Bommareddy, GW Black, W Singh, M Huang Catalysis Science & Technology 13 (7), 2070-2079, 2023 | 2 | 2023 |
| Thebaine is Selectively Demethylated by Thebaine 6-O-Demethylase and Codeine-3-O-demethylase at Distinct Binding Sites: A Computational Study W Singh, C Hui, C Li, M Huang Inorganic Chemistry 60 (14), 10199-10214, 2021 | 2 | 2021 |
| Substrate Conformation Regulates Aromatic C–H Vs C–F Bond Activation in Heme-Dependent Tyrosine Hydroxylase W Singh, SFG Santos, S Yadav, GW Black, KD Dubey Biochemistry 62 (10), 1577-1587, 2023 | 1 | 2023 |
Meilan Huang PhD FRSC FRSBQueen's University BelfastBestätigte E-Mail-Adresse bei qub.ac.uk
