| A molecular trigger for intercontinental epidemics of group A Streptococcus L Zhu, RJ Olsen, W Nasser, SB Beres, J Vuopio, KG Kristinsson, ... The Journal of Clinical Investigation 125 (9), 3545-3559, 2015 | 124 | 2015 |
| Trading capsule for increased cytotoxin production: Contribution to virulence of a newly emerged clade of emm89 Streptococcus pyogenes L Zhu, RJ Olsen, W Nasser, I de la Riva Morales, JM Musser MBio 6 (5), e01378-15, 2015 | 87 | 2015 |
| Inhibition of Competence Development, Horizontal Gene Transfer and Virulence in Streptococcus pneumoniae by a Modified Competence Stimulating Peptide L Zhu, GW Lau PLoS pathogens 7 (9), e1002241, 2011 | 82 | 2011 |
| Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis P Kachroo, JM Eraso, SB Beres, RJ Olsen, L Zhu, W Nasser, PE Bernard, ... Nature genetics 51 (3), 548-559, 2019 | 70 | 2019 |
| Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread JM Musser, SB Beres, L Zhu, RJ Olsen, J Vuopio, HL Hyyryläinen, ... Journal of clinical microbiology 58 (4), 10.1128/jcm. 01993-19, 2020 | 67 | 2020 |
| Contribution of secreted NADase and streptolysin O to the pathogenesis of epidemic serotype M1 Streptococcus pyogenes infections L Zhu, RJ Olsen, JD Lee, AR Porter, FR DeLeo, JM Musser The American journal of pathology 187 (3), 605-613, 2017 | 64 | 2017 |
| Transcriptome remodeling contributes to epidemic disease caused by the human pathogen Streptococcus pyogenes SB Beres, P Kachroo, W Nasser, RJ Olsen, L Zhu, AR Flores, I de la Riva, ... MBio 7 (3), 10.1128/mbio. 00403-16, 2016 | 54 | 2016 |
| Deletion analysis of Streptococcus pneumoniae late competence genes distinguishes virulence determinants that are dependent or independent of competence … L Zhu, J Lin, Z Kuang, JE Vidal, GW Lau Molecular microbiology 97 (1), 151-165, 2015 | 45 | 2015 |
| Disentangling competence for genetic transformation and virulence in Streptococcus pneumoniae J Lin, L Zhu, GW Lau Current genetics 62, 97-103, 2016 | 35 | 2016 |
| Gene fitness landscape of group A streptococcus during necrotizing myositis L Zhu, RJ Olsen, SB Beres, JM Eraso, MO Saavedra, SL Kubiak, ... The Journal of clinical investigation 129 (2), 887-901, 2019 | 34 | 2019 |
| Competence-independent activity of pneumococcal EndA mediates degradation of extracellular DNA and NETs and is important for virulence L Zhu, Z Kuang, BA Wilson, GW Lau PLoS One 8 (7), e70363, 2013 | 34 | 2013 |
| Population genomic molecular epidemiological study of macrolide-resistant Streptococcus pyogenes in Iceland, 1995 to 2016: identification of a large clonal population with a … SB Southon, SB Beres, P Kachroo, MO Saavedra, H Erlendsdóttir, ... Journal of clinical microbiology 58 (9), 10.1128/jcm. 00638-20, 2020 | 32 | 2020 |
| Novel genes required for the fitness of Streptococcus pyogenes in human saliva L Zhu, ARL Charbonneau, AS Waller, RJ Olsen, SB Beres, JM Musser Msphere 2 (6), 10.1128/mspheredirect. 00460-17, 2017 | 31* | 2017 |
| Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes L Zhu, RJ Olsen, N Horstmann, SA Shelburne, J Fan, Y Hu, JM Musser Infection and immunity 84 (7), 2086-2093, 2016 | 21 | 2016 |
| New pathogenesis mechanisms and translational leads identified by multidimensional analysis of necrotizing myositis in primates P Kachroo, JM Eraso, RJ Olsen, L Zhu, SL Kubiak, L Pruitt, P Yerramilli, ... MBio 11 (1), 2020 | 20* | 2020 |
| Saturated alanine scanning mutagenesis of the pneumococcus competence stimulating peptide identifies analogs that inhibit genetic transformation C Duan, L Zhu, Y Xu, GW Lau Public Library of Science 7 (9), e44710, 2012 | 17 | 2012 |
| RocA has serotype-specific gene regulatory and pathogenesis activities in serotype M28 group A streptococcus PE Bernard, P Kachroo, L Zhu, SB Beres, JM Eraso, Z Kajani, SW Long, ... Infection and Immunity 86 (11), 10.1128/iai. 00467-18, 2018 | 16 | 2018 |
| Integrative Reverse Genetic Analysis Identifies Polymorphisms Contributing to Decreased Antimicrobial Agent Susceptibility in Streptococcus pyogenes SB Beres, L Zhu, L Pruitt, RJ Olsen, A Faili, S Kayal, JM Musser Mbio 13 (1), e03618-21, 2022 | 14 | 2022 |
| A single amino acid replacement in penicillin-binding protein 2X in Streptococcus pyogenes significantly increases fitness on subtherapeutic benzylpenicillin treatment in a … RJ Olsen, L Zhu, JM Musser The American Journal of Pathology 190 (8), 1625-1631, 2020 | 13 | 2020 |
| Genome-wide screens identify group A Streptococcus surface proteins promoting female genital tract colonization and virulence L Zhu, RJ Olsen, SB Beres, MO Saavedra, SL Kubiak, CC Cantu, ... The American Journal of Pathology 190 (4), 862-873, 2020 | 13 | 2020 |
