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Saskia Haupt
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The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ...
Nature Communications 11 (1), 4740, 2020
982020
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
P Møller, T Seppälä, JG Dowty, S Haupt, M Dominguez-Valentin, L Sunde, ...
Hereditary cancer in clinical practice 20 (1), 36, 2022
232022
Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics
H Bläker, S Haupt, M Morak, E Holinski‐Feder, A Arnold, D Horst, ...
International Journal of Cancer, 0
20
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the …
M Dominguez-Valentin, S Haupt, TT Seppälä, JR Sampson, L Sunde, ...
EClinicalMedicine 58, 2023
162023
Opportunities and challenges in machine learning‐based newborn screening—A systematic literature review
E Zaunseder, S Haupt, U Mütze, SF Garbade, S Kölker, V Heuveline
JIMD reports 63 (3), 250-261, 2022
152022
Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure
S Haupt, A Zeilmann, A Ahadova, H Bläker, M von Knebel Doeberitz, ...
PLOS Computational Biology 17 (5), e1008970, 2021
152021
Hiflow3–technical report on release 2.0
S Gawlok, P Gerstner, S Haupt, V Heuveline, J Kratzke, P Lösel, K Mang, ...
Preprint Series of the Engineering Mathematics and Computing Lab, 2017
142017
Machine Learning Methods Improve Specificity in Newborn Screening for Isovaleric Aciduria
E Zaunseder, U Mütze, SF Garbade, S Haupt, P Feyh, GF Hoffmann, ...
Metabolites 13 (2), 304, 2023
82023
A “two-in-one hit” model of shortcut carcinogenesis in MLH1 lynch syndrome carriers
A Ahadova, A Stenzinger, T Seppälä, R Hüneburg, M Kloor, H Bläker, ...
Gastroenterology 165 (1), 267-270. e4, 2023
72023
Is HLA type a possible cancer risk modifier in Lynch syndrome?
A Ahadova, J Witt, S Haupt, R Gallon, R Hüneburg, J Nattermann, ...
International Journal of Cancer 152 (10), 2024-2031, 2023
72023
The shared neoantigen landscape of MSI cancers reflects immunoediting during tumor evolution
A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ...
BioRxiv, 691469, 2019
72019
Dominantly inherited micro-satellite instable cancer–the four Lynch syndromes-an EHTG, PLSD position statement
P Møller, TT Seppälä, A Ahadova, EJ Crosbie, E Holinski-Feder, R Scott, ...
Hereditary Cancer in Clinical Practice 21 (1), 19, 2023
42023
A simple approach for detecting HLA‐A*02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer …
J Witt, S Haupt, A Ahadova, L Bohaumilitzky, V Fuchs, A Ballhausen, ...
HLA 101 (1), 24-33, 2023
32023
A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis
S Haupt, N Gleim, A Ahadova, H Bläker, M von Knebel Doeberitz, M Kloor, ...
Computational and Systems Oncology 1 (2), e1020, 2021
32021
BRAF mutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient’s age
H Bläker, S Haupt, M Morak, E Holinski-Feder, A Arnold, D Horst, ...
medRxiv, 19009274, 2019
12019
Deep Learning and Explainable Artificial Intelligence for Improving Specificity and Detecting Metabolic Patterns in Newborn Screening
E Zaunseder, U Mütze, SF Garbade, S Haupt, S Kölker, V Heuveline
2023 IEEE Symposium Series on Computational Intelligence (SSCI), 1566-1571, 2023
2023
Mathematical modeling of Lynch syndrome carcinogenesis
S Haupt
2023
Unraveling the black boxes in early cancer development using mathematical modeling at different scales
S Haupt, A Zeilmann, N Gleim, A Ahadova, H Bläker, ...
2022 Virtual Joint Mathematics Meetings (JMM 2022), 2022
2022
Modeling multiple pathways of carcinogenesis using the Kronecker structure
S Haupt
The Mathematical Oncology Blog, 2021
2021
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Articles 1–19