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Saskia Haupt
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The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ...
Nature Communications 11 (1), 4740, 2020
1062020
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
P Møller, T Seppälä, JG Dowty, S Haupt, M Dominguez-Valentin, L Sunde, ...
Hereditary cancer in clinical practice 20 (1), 36, 2022
312022
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the …
M Dominguez-Valentin, S Haupt, TT Seppälä, JR Sampson, L Sunde, ...
EClinicalMedicine 58, 2023
272023
Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics
H Bläker, S Haupt, M Morak, E Holinski‐Feder, A Arnold, D Horst, ...
International Journal of Cancer, 0
22
Opportunities and challenges in machine learning‐based newborn screening—A systematic literature review
E Zaunseder, S Haupt, U Mütze, SF Garbade, S Kölker, V Heuveline
JIMD reports 63 (3), 250-261, 2022
182022
Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure
S Haupt, A Zeilmann, A Ahadova, H Bläker, M von Knebel Doeberitz, ...
PLOS Computational Biology 17 (5), e1008970, 2021
162021
Hiflow3–technical report on release 2.0
S Gawlok, P Gerstner, S Haupt, V Heuveline, J Kratzke, P Lösel, K Mang, ...
Preprint Series of the Engineering Mathematics and Computing Lab, 2017
162017
A “two-in-one hit” model of shortcut carcinogenesis in MLH1 lynch syndrome carriers
A Ahadova, A Stenzinger, T Seppälä, R Hüneburg, M Kloor, H Bläker, ...
Gastroenterology 165 (1), 267-270. e4, 2023
112023
Machine Learning Methods Improve Specificity in Newborn Screening for Isovaleric Aciduria
E Zaunseder, U Mütze, SF Garbade, S Haupt, P Feyh, GF Hoffmann, ...
Metabolites 13 (2), 304, 2023
92023
Is HLA type a possible cancer risk modifier in Lynch syndrome?
A Ahadova, J Witt, S Haupt, R Gallon, R Hüneburg, J Nattermann, ...
International Journal of Cancer 152 (10), 2024-2031, 2023
82023
Dominantly inherited micro-satellite instable cancer–the four Lynch syndromes-an EHTG, PLSD position statement
P Møller, TT Seppälä, A Ahadova, EJ Crosbie, E Holinski-Feder, R Scott, ...
Hereditary Cancer in Clinical Practice 21 (1), 19, 2023
72023
The shared neoantigen landscape of MSI cancers reflects immunoediting during tumor evolution
A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ...
BioRxiv, 691469, 2019
72019
A simple approach for detecting HLA‐A*02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer …
J Witt, S Haupt, A Ahadova, L Bohaumilitzky, V Fuchs, A Ballhausen, ...
HLA 101 (1), 24-33, 2023
32023
A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis
S Haupt, N Gleim, A Ahadova, H Bläker, M von Knebel Doeberitz, M Kloor, ...
Computational and Systems Oncology 1 (2), e1020, 2021
32021
BRAF mutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient’s age
H Bläker, S Haupt, M Morak, E Holinski-Feder, A Arnold, D Horst, ...
medRxiv, 19009274, 2019
12019
Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated “Big Bang” pathway to CRC in three of the four Lynch syndromes
P Møller, S Haupt, A Ahadova, M Kloor, JR Sampson, L Sunde, T Seppälä, ...
Hereditary Cancer in Clinical Practice 22 (1), 6, 2024
2024
Deep Learning and Explainable Artificial Intelligence for Improving Specificity and Detecting Metabolic Patterns in Newborn Screening
E Zaunseder, U Mütze, SF Garbade, S Haupt, S Kölker, V Heuveline
2023 IEEE Symposium Series on Computational Intelligence (SSCI), 1566-1571, 2023
2023
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: A report from the …
M Dominguez-Valentin, S Haupt, TT Seppälä, JR Sampson, L Sunde, ...
DOI: https://doi. org/10.1016/j. eclinm, 101909, 2023
2023
Mathematical modeling of Lynch syndrome carcinogenesis
S Haupt
2023
Unraveling the black boxes in early cancer development using mathematical modeling at different scales
S Haupt, A Zeilmann, N Gleim, A Ahadova, H Bläker, ...
2022 Virtual Joint Mathematics Meetings (JMM 2022), 2022
2022
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