|Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells|
PSR Simonini, A Breiling, N Gupta, M Malekpour, M Youns, R Omranipour, ...
Cancer research 70 (22), 9175-9184, 2010
|Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer|
A Ward, A Balwierz, JD Zhang, M Küblbeck, Y Pawitan, T Hielscher, ...
Oncogene 32 (9), 1173-1182, 2013
|MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways|
I Keklikoglou, C Koerner, C Schmidt, JD Zhang, D Heckmann, ...
Oncogene 31 (37), 4150-4163, 2012
|MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F|
S Jurmeister, M Baumann, A Balwierz, I Keklikoglou, A Ward, S Uhlmann, ...
Molecular and cellular biology 32 (3), 633-651, 2012
|miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer|
S Uhlmann, JD Zhang, A Schwäger, H Mannsperger, Y Riazalhosseini, ...
Oncogene 29 (30), 4297-4306, 2010
|Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance|
Ö Sahin, H Fröhlich, C Löbke, U Korf, S Burmester, M Majety, J Mattern, ...
BMC systems biology 3 (1), 1, 2009
|Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer|
S Uhlmann, H Mannsperger, JD Zhang, EÁ Horvat, C Schmidt, ...
Molecular systems biology 8 (1), 570, 2012
|Localization‐and mutation‐dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co‐expressed miRNAs located at 14q32. 31|
F Haller, A Von Heydebreck, JD Zhang, B Gunawan, C Langer, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010
|14-3-3ζ turns TGF-β’s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2|
J Xu, S Acharya, O Sahin, Q Zhang, Y Saito, J Yao, H Wang, P Li, L Zhang, ...
Cancer cell 27 (2), 177-192, 2015
|MicroRNA‐519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour‐suppressor genes in ER+ breast cancer|
A Ward, K Shukla, A Balwierz, Z Soons, R König, Ö Sahin, S Wiemann
The Journal of pathology 233 (4), 368-379, 2014
|miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance|
M Mutlu, U Raza, Ö Saatci, E Eyüpoğlu, E Yurdusev, Ö Şahin
Journal of Molecular Medicine 94 (6), 629-644, 2016
|Combinatorial targeting of FGF and ErbB receptors blocks growth and metastatic spread of breast cancer models|
A Issa, JW Gill, MR Heideman, O Sahin, S Wiemann, JH Dey, NE Hynes
Breast Cancer Research 15 (1), 1-16, 2013
|MicroRNAs: master regulators of drug resistance, stemness, and metastasis|
U Raza, JD Zhang, Ö Şahin
Journal of molecular medicine 92 (4), 321-336, 2014
|Combinatorial RNAi for quantitative protein network analysis|
Ö Sahin, C Löbke, U Korf, H Appelhans, H Sültmann, A Poustka, ...
Proceedings of the National Academy of Sciences 104 (16), 6579-6584, 2007
|Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells|
M Sauermann, Ö Sahin, H Sültmann, F Hahne, S Blaszkiewicz, M Majety, ...
Oncogene 27 (9), 1320-1326, 2008
|Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer|
Q Wang, SH Li, H Wang, Y Xiao, O Sahin, SW Brady, P Li, H Ge, ...
Cancer research 72 (17), 4417-4428, 2012
|miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer|
M Mutlu, Ö Saatci, SA Ansari, E Yurdusev, H Shehwana, Ö Konu, U Raza, ...
Scientific reports 6, 32541, 2016
|The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer.|
U Raza, Ö Saatci, S Uhlmann, S Ansari, E Eyüpoglu, E Yurdusev, M Mutlu, ...
|Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors|
O Sahin, Q Wang, SW Brady, K Ellis, H Wang, CC Chang, Q Zhang, ...
Cell research 24 (5), 542-559, 2014
|Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions|
H Fröhlich, Ö Sahin, D Arlt, C Bender, T Beißbarth
BMC bioinformatics 10 (1), 322, 2009