Pulling geometry defines the mechanical resistance of a β-sheet protein DJ Brockwell, E Paci, RC Zinober, GS Beddard, PD Olmsted, DA Smith, ... Nature Structural & Molecular Biology 10 (9), 731-737, 2003 | 447 | 2003 |
Intermediates: ubiquitous species on folding energy landscapes? DJ Brockwell, SE Radford Current opinion in structural biology 17 (1), 30-37, 2007 | 297 | 2007 |
Tuning the elastic modulus of hydrated collagen fibrils CA Grant, DJ Brockwell, SE Radford, NH Thomson Biophysical journal 97 (11), 2985-2992, 2009 | 194 | 2009 |
Mechanically unfolding the small, topologically simple protein L DJ Brockwell, GS Beddard, E Paci, DK West, PD Olmsted, DA Smith, ... Biophysical journal 89 (1), 506-519, 2005 | 194 | 2005 |
Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM MG Iadanza, AJ Higgins, B Schiffrin, AN Calabrese, DJ Brockwell, ... Nature communications 7 (1), 12865, 2016 | 191 | 2016 |
Protein folding mechanisms: new methods and emerging ideas DJ Brockwell, DA Smith, SE Radford Current opinion in structural biology 10 (1), 16-25, 2000 | 174 | 2000 |
Effects of hydration on the mechanical response of individual collagen fibrils CA Grant, DJ Brockwell, SE Radford, NH Thomson Applied Physics Letters 92 (23), 2008 | 164 | 2008 |
Force mode atomic force microscopy as a tool for protein folding studies RB Best, DJ Brockwell, JL Toca-Herrera, AW Blake, DA Smith, ... Analytica Chimica Acta 479 (1), 87-105, 2003 | 164 | 2003 |
The effect of core destabilization on the mechanical resistance of I27 DJ Brockwell, GS Beddard, J Clarkson, RC Zinober, AW Blake, J Trinick, ... Biophysical journal 83 (1), 458-472, 2002 | 159 | 2002 |
The transition state for folding of an outer membrane protein GHM Huysmans, SA Baldwin, DJ Brockwell, SE Radford Proceedings of the National Academy of Sciences 107 (9), 4099-4104, 2010 | 153 | 2010 |
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function CPA Doherty, SM Ulamec, R Maya-Martinez, SC Good, J Makepeace, ... Nature structural & molecular biology 27 (3), 249-259, 2020 | 141 | 2020 |
Mechanical resistance of proteins explained using simple molecular models DK West, DJ Brockwell, PD Olmsted, SE Radford, E Paci Biophysical journal 90 (1), 287-297, 2006 | 132 | 2006 |
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria JE Horne, DJ Brockwell, SE Radford Journal of Biological Chemistry 295 (30), 10340-10367, 2020 | 109 | 2020 |
Inducing protein aggregation by extensional flow J Dobson, A Kumar, LF Willis, R Tuma, DR Higazi, R Turner, DC Lowe, ... Proceedings of the National Academy of Sciences 114 (18), 4673-4678, 2017 | 100 | 2017 |
Skp is a multivalent chaperone of outer-membrane proteins B Schiffrin, AN Calabrese, PWA Devine, SA Harris, AE Ashcroft, ... Nature structural & molecular biology 23 (9), 786-793, 2016 | 100 | 2016 |
De novo design of transmembrane β barrels AA Vorobieva, P White, B Liang, JE Horne, AK Bera, CM Chow, S Gerben, ... Science 371 (6531), eabc8182, 2021 | 97 | 2021 |
An in vivo platform for identifying inhibitors of protein aggregation JC Saunders, LM Young, RA Mahood, MP Jackson, CH Revill, RJ Foster, ... Nature chemical biology 12 (2), 94-101, 2016 | 93 | 2016 |
Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold RC Zinober, DJ Brockwell, GS Beddard, AW Blake, PD Olmsted, ... Protein science 11 (12), 2759-2765, 2002 | 92 | 2002 |
Gating of TonB-dependent transporters by substrate-specific forced remodelling SJ Hickman, REM Cooper, L Bellucci, E Paci, DJ Brockwell Nature communications 8 (1), 14804, 2017 | 81 | 2017 |
Outer membrane protein folding from an energy landscape perspective B Schiffrin, DJ Brockwell, SE Radford BMC biology 15, 1-16, 2017 | 80 | 2017 |