Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes I Ullah, GM Karthik, A Alkodsi, U Kjällquist, G Stålhammar, J Lövrot, ... The Journal of clinical investigation 128 (4), 1355-1370, 2018 | 139 | 2018 |
A functional homologous recombination assay predicts primary chemotherapy response and long-term survival in ovarian cancer patients M Tumiati, S Hietanen, J Hynninen, E Pietilä, A Färkkilä, K Kaipio, ... Clinical Cancer Research 24 (18), 4482-4493, 2018 | 101 | 2018 |
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans E Kaasinen, O Kuismin, K Rajamäki, H Ristolainen, M Aavikko, J Kondelin, ... Nature communications 10 (1), 1252, 2019 | 76 | 2019 |
Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability N Välimäki, H Kuisma, A Pasanen, O Heikinheimo, J Sjöberg, R Bützow, ... Elife 7, e37110, 2018 | 75 | 2018 |
Comparative analysis of methods for identifying somatic copy number alterations from deep sequencing data A Alkodsi, R Louhimo, S Hautaniemi Briefings in bioinformatics 16 (2), 242-254, 2015 | 70 | 2015 |
Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma L Meriranta, A Alkodsi, A Pasanen, M Lepistö, P Mapar, YN Blaker, ... Blood, The Journal of the American Society of Hematology 139 (12), 1863-1877, 2022 | 54 | 2022 |
Anduril 2: upgraded large-scale data integration framework A Cervera, V Rantanen, K Ovaska, M Laakso, J Nunez-Fontarnau, ... Bioinformatics 35 (19), 3815-3817, 2019 | 35 | 2019 |
Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes A Alkodsi, A Cervera, K Zhang, R Louhimo, L Meriranta, A Pasanen, ... Leukemia 33 (11), 2662-2672, 2019 | 30 | 2019 |
MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma SK Leivonen, K Icay, K Jäntti, I Siren, C Liu, A Alkodsi, A Cervera, ... Blood cancer journal 7 (12), 654, 2017 | 30 | 2017 |
Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs) U Kjällquist, R Erlandsson, NP Tobin, A Alkodsi, I Ullah, G Stålhammar, ... BMC cancer 18, 1-17, 2018 | 27 | 2018 |
Molecular background delineates outcome of double protein expressor diffuse large B-cell lymphoma L Meriranta, A Pasanen, A Alkodsi, J Haukka, ML Karjalainen-Lindsberg, ... Blood advances 4 (15), 3742-3753, 2020 | 25 | 2020 |
Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma L Meriranta, A Pasanen, R Louhimo, A Cervera, A Alkodsi, M Autio, ... Haematologica 102 (5), e195, 2017 | 23 | 2017 |
PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples A Häkkinen, K Zhang, A Alkodsi, N Andersson, EP Erkan, J Dai, K Kaipio, ... Bioinformatics 37 (18), 2882-2888, 2021 | 17 | 2021 |
Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling GM Karthik, M Rantalainen, G Stålhammar, J Lövrot, I Ullah, A Alkodsi, ... BMC cancer 17, 1-11, 2017 | 15 | 2017 |
Lung metastases and subsequent malignant transformation of a fumarate hydratase-deficient uterine leiomyoma T Ahvenainen, S Khamaiseh, A Alkodsi, M Mehine, R Nevala, ... Experimental and Molecular Pathology 126, 104760, 2022 | 6 | 2022 |
Identifying differentially methylated sites in samples with varying tumor purity A Häkkinen, A Alkodsi, C Facciotto, K Zhang, K Kaipio, S Leppä, ... Bioinformatics 34 (18), 3078-3085, 2018 | 5 | 2018 |
ctDNAtools: An R package to work with sequencing data of circulating tumor DNA A Alkodsi, L Meriranta, A Pasanen, S Leppä bioRxiv, 2020.01. 27.912790, 2020 | 3 | 2020 |
PRISM: Recovering cell type specific expression profiles from composite RNA-seq data A Häkkinen, K Zhang, A Alkodsi, N Andersson, EP Erkan, J Dai, K Kaipio, ... bioRxiv, 854505, 2019 | 1 | 2019 |
Genomic profiling of circulating tumor DNA reveals patterns of response and refractoriness in aggressive B-cell lymphoma-a nordic lymphoma group correlative study L Meriranta, A Alkodsi, A Pasanen, M Lepistö, YN Blaker, M Autio, ... Blood 134, 1481, 2019 | 1 | 2019 |
ESR1, WT1, WNT4, ATM and TERT loci are major contributors to uterine leiomyoma predisposition N Välimäki, H Kuisma, A Pasanen, O Heikinheimo, J Sjöberg, R Bützow, ... bioRxiv, 291237, 2018 | 1 | 2018 |