Dirk Fey
Cited by
Cited by
Crosstalk and signaling switches in mitogen-activated protein kinase cascades
D Fey, DR Croucher, W Kolch, BN Kholodenko
Frontiers in physiology 3, 355, 2012
Frequency modulation of ERK activation dynamics rewires cell fate
H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, SS Lee, M Peter, ...
Molecular systems biology 11 (11), 838, 2015
Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients
D Fey, M Halasz, D Dreidax, SP Kennedy, JF Hastings, N Rauch, ...
Science signaling 8 (408), ra130-ra130, 2015
The extracellular matrix as a key regulator of intracellular signalling networks
JF Hastings, JN Skhinas, D Fey, DR Croucher, TR Cox
British journal of pharmacology 176 (1), 82-92, 2019
Exact model reduction of combinatorial reaction networks
H Conzelmann, D Fey, ED Gilles
BMC systems biology 2 (1), 1-25, 2008
The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells
D Fey, D Matallanas, J Rauch, OS Rukhlenko, BN Kholodenko
Seminars in cell & developmental biology 58, 96-107, 2016
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells
S Rogers, D Fey, RA McCloy, BL Parker, NJ Mitchell, RJ Payne, RJ Daly, ...
Journal of cell science 129 (7), 1340-1354, 2016
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2
V Reiterer, D Fey, W Kolch, BN Kholodenko, H Farhan
Proceedings of the National Academy of Sciences 110 (31), E2934-E2943, 2013
MASTL overexpression promotes chromosome instability and metastasis in breast cancer
S Rogers, RA McCloy, BL Parker, D Gallego-Ortega, AMK Law, VT Chin, ...
Oncogene 37 (33), 4518-4533, 2018
Performance of objective functions and optimisation procedures for parameter estimation in system biology models
A Degasperi, D Fey, BN Kholodenko
NPJ systems biology and applications 3 (1), 20, 2017
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ...
Oncotarget 6 (41), 43182, 2015
Wnt signalling is a bi-directional vulnerability of cancer cells
DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ...
Oncotarget 7 (37), 60310, 2016
Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation
LK Nguyen, M Dobrzyński, D Fey, BN Kholodenko
Frontiers in physiology 5, 4, 2014
Frequency modulation of ERK activation dynamics rewires cell fate
H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, SS Lee, M Peter, ...
Molecular systems biology 12 (4), 2016
Parameter estimation in kinetic reaction models using nonlinear observers facilitated by model extensions
D Fey, R Findeisen, E Bullinger
Proc. 17th IFAC World Congres, Seoul, 313-318, 2008
Personalized computational models as biomarkers
W Kolch, D Fey
Journal of personalized medicine 7 (3), 9, 2017
Applications of personalised signalling network models in precision oncology
JF Hastings, YEI O'Donnell, D Fey, DR Croucher
Pharmacology & Therapeutics 212, 107555, 2020
Control of the G-protein cascade dynamics by GDP dissociation inhibitors
E Nikonova, MA Tsyganov, W Kolch, D Fey, BN Kholodenko
Molecular bioSystems 9 (10), 2454-2462, 2013
Accurate prediction of kinase-substrate networks using knowledge graphs
V Nováček, G McGauran, D Matallanas, A Vallejo Blanco, P Conca, ...
PLoS computational biology 16 (12), e1007578, 2020
BAX and SMAC regulate bistable properties of the apoptotic caspase system
S McKenna, L García-Gutiérrez, D Matallanas, D Fey
Scientific reports 11 (1), 3272, 2021
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Articles 1–20