| Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis S Kothakota, T Azuma, C Reinhard, A Klippel, J Tang, K Chu, TJ McGarry, ... Science 278 (5336), 294-298, 1997 | 1776 | 1997 |
| Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt G Kulik, A Klippel, MJ Weber Molecular and cellular biology 17 (3), 1595-1606, 1997 | 1356 | 1997 |
| Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells F Czauderna, M Fechtner, S Dames, HÈ AyguÈn, A Klippel, GJ Pronk, ... Nucleic acids research 31 (11), 2705-2716, 2003 | 957 | 2003 |
| Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase Q Hu, A Klippel, AJ Muslin, WJ Fantl, LT Williams Science 268 (5207), 100-102, 1995 | 692 | 1995 |
| A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain A Klippel, WM Kavanaugh, D Pot, LT Williams Molecular and cellular biology, 1997 | 680 | 1997 |
| Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin … AK Gandhi, J Kang, CG Havens, T Conklin, Y Ning, L Wu, T Ito, H Ando, ... British journal of haematology 164 (6), 811-821, 2014 | 634 | 2014 |
| Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways A Klippel, C Reinhard, WM Kavanaugh, G Apell, MA Escobedo, ... Molecular and cellular biology 16 (8), 4117-4127, 1996 | 611 | 1996 |
| A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium A Santel, M Aleku, O Keil, J Endruschat, V Esche, G Fisch, S Dames, ... Gene therapy 13 (16), 1222-1234, 2006 | 496 | 2006 |
| Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons KL Philpott, MJ McCarthy, A Klippel, LL Rubin The Journal of cell biology 139 (3), 809-815, 1997 | 332 | 1997 |
| Interfering RNA molecules K Giese, J Kaufmann, A Klippel-Giese US Patent 7,452,987, 2008 | 330 | 2008 |
| Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation A Klippel, MA Escobedo, MS Wachowicz, G Apell, TW Brown, MA Giedlin, ... Molecular and cellular biology 18 (10), 5699-5711, 1998 | 323 | 1998 |
| Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. G Li, C D'Souza-Schorey, MA Barbieri, RL Roberts, A Klippel, LT Williams, ... Proceedings of the National Academy of Sciences 92 (22), 10207-10211, 1995 | 323 | 1995 |
| Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes SS Martin, T Haruta, AJ Morris, A Klippel, LT Williams, JM Olefsky Journal of Biological Chemistry 271 (30), 17605-17608, 1996 | 309 | 1996 |
| RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy A Santel, M Aleku, O Keil, J Endruschat, V Esche, B Durieux, K Löffler, ... Gene therapy 13 (18), 1360-1370, 2006 | 260 | 2006 |
| Inducible shRNA expression for application in a prostate cancer mouse model F Czauderna, A Santel, M Hinz, M Fechtner, B Durieux, G Fisch, ... Nucleic acids research 31 (21), e127-e127, 2003 | 252 | 2003 |
| Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. QP Weng, K Andrabi, A Klippel, MT Kozlowski, LT Williams, J Avruch Proceedings of the National Academy of Sciences 92 (12), 5744-5748, 1995 | 244 | 1995 |
| Rate of CRL4CRBN substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4 CC Bjorklund, L Lu, J Kang, PR Hagner, CG Havens, M Amatangelo, ... Blood cancer journal 5 (10), e354-e354, 2015 | 207 | 2015 |
| Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence SB Cichy, S Uddin, A Danilkovich, S Guo, A Klippel, TG Unterman Journal of Biological Chemistry 273 (11), 6482-6487, 1998 | 206 | 1998 |
| Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4 A Kretschmer, K Moepert, S Dames, M Sternberger, J Kaufmann, ... Oncogene 22 (43), 6748-6763, 2003 | 201 | 2003 |
| Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes JF Tanti, T Grémeaux, S Grillo, V Calleja, A Klippel, LT Williams, ... Journal of Biological Chemistry 271 (41), 25227-25232, 1996 | 195 | 1996 |
