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John A. Tallarico
John A. Tallarico
Novartis Institutes for Biomedical Research
Bestätigte E-Mail-Adresse bei novartis.com
Titel
Zitiert von
Zitiert von
Jahr
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614-620, 2009
21712009
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
WE Dowdle, B Nyfeler, J Nagel, RA Elling, S Liu, E Triantafellow, ...
Nature cell biology 16 (11), 1069-1079, 2014
6462014
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
KJ Mavrakis, ER McDonald III, MR Schlabach, E Billy, GR Hoffman, ...
Science 351 (6278), 1208-1213, 2016
4242016
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4152015
Integrating high-content screening and ligand-target prediction to identify mechanism of action
DW Young, A Bender, J Hoyt, E McWhinnie, GW Chirn, CY Tao, ...
Nature chemical biology 4 (1), 59-68, 2008
3952008
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds
Y Feng, TJ Mitchison, A Bender, DW Young, JA Tallarico
Nature Reviews Drug Discovery 8 (7), 567-578, 2009
3242009
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ...
Nature chemical biology 15 (7), 747-755, 2019
3062019
Natural products reveal cancer cell dependence on oxysterol-binding proteins
AWG Burgett, TB Poulsen, K Wangkanont, DR Anderson, C Kikuchi, ...
Nature chemical biology 7 (9), 639-647, 2011
2542011
Selective and specific inhibition of the Plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin
D Hoepfner, CW McNamara, CS Lim, C Studer, R Riedl, T Aust, ...
Cell host & microbe 11 (6), 654-663, 2012
2392012
Ring-opening metathesis. A ruthenium catalyst caught in the act
JA Tallarico, PJ Bonitatebus, ML Snapper
Journal of the American Chemical Society 119 (30), 7157-7158, 1997
2371997
Covalent ligand screening uncovers a RNF4 E3 ligase recruiter for targeted protein degradation applications
CC Ward, JI Kleinman, SM Brittain, PS Lee, CYS Chung, K Kim, Y Petri, ...
ACS chemical biology 14 (11), 2430-2440, 2019
2302019
Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication
J Borawski, P Troke, X Puyang, V Gibaja, SC Zhao, C Mickanin, ...
Journal of virology 83 (19), 10058-10074, 2009
2102009
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling
X Cai, Y Xu, AK Cheung, RC Tomlinson, A Alcázar-Román, L Murphy, ...
Chemistry & biology 20 (7), 912-921, 2013
2042013
Small molecules that delay S phase suppress a zebrafish bmyb mutant
HM Stern, RD Murphey, JL Shepard, JF Amatruda, CT Straub, KL Pfaff, ...
Nature chemical biology 1 (7), 366-370, 2005
1932005
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions
D Hoepfner, SB Helliwell, H Sadlish, S Schuierer, I Filipuzzi, S Brachat, ...
Microbiological research 169 (2-3), 107-120, 2014
1632014
Deubiquitinase-targeting chimeras for targeted protein stabilization
NJ Henning, L Boike, JN Spradlin, CC Ward, G Liu, E Zhang, BP Belcher, ...
Nature chemical biology 18 (4), 412-421, 2022
1532022
A one-bead, one-stock solution approach to chemical genetics: part 1
HE Blackwell, L Pérez, RA Stavenger, JA Tallarico, EC Eatough, ...
Chemistry & biology 8 (12), 1167-1182, 2001
1532001
Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62
R DeJesus, F Moretti, G McAllister, Z Wang, P Bergman, S Liu, E Frias, ...
Elife 5, e17290, 2016
1402016
An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics
JA Tallarico, KM Depew, HE Pelish, NJ Westwood, CW Lindsley, ...
Journal of combinatorial chemistry 3 (3), 312-318, 2001
1362001
Selective ring-opening cross-metathesis. Short syntheses of multifidene and viridiene
ML Randall, JA Tallarico, ML Snapper
Journal of the American Chemical Society 117 (37), 9610-9611, 1995
1331995
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