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Patrice Leroy
Patrice Leroy
Statistician, Philip Morris International
Bestätigte E-Mail-Adresse bei pmi.com
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Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by …
B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ...
Food and chemical toxicology 109, 315-332, 2017
1282017
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/− Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate …
B Phillips, E Veljkovic, S Boué, WK Schlage, G Vuillaume, F Martin, B Titz, ...
Toxicological Sciences 149 (2), 411-432, 2016
1202016
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with …
ET Wong, U Kogel, E Veljkovic, F Martin, Y Xiang, S Boue, G Vuillaume, ...
Regulatory Toxicology and Pharmacology 81, S59-S81, 2016
922016
A framework for in vitro systems toxicology assessment of e-liquids
AR Iskandar, I Gonzalez-Suarez, S Majeed, D Marescotti, A Sewer, ...
Toxicology Mechanisms and Methods 26 (6), 392-416, 2016
912016
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared …
U Kogel, WK Schlage, F Martin, Y Xiang, S Ansari, P Leroy, ...
Food and chemical toxicology 68, 204-217, 2014
812014
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe−/− Mice—An …
B Titz, S Boué, B Phillips, M Talikka, T Vihervaara, T Schneider, C Nury, ...
Toxicological Sciences 149 (2), 441-457, 2016
772016
Characterization of the Vitrocell® 24/48 in vitroaerosol exposure system using mainstream cigarette smoke
S Majeed, S Frentzel, S Wagner, D Kuehn, P Leroy, PA Guy, A Knorr, ...
Chemistry Central Journal 8, 1-11, 2014
762014
3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product
AR Iskandar, C Mathis, F Martin, P Leroy, A Sewer, S Majeed, D Kuehn, ...
ALTEX-Alternatives to animal experimentation 34 (1), 23-48, 2017
682017
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a …
A Oviedo, S Lebrun, U Kogel, J Ho, WT Tan, B Titz, P Leroy, G Vuillaume, ...
Regulatory Toxicology and Pharmacology 81, S93-S122, 2016
682016
A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human …
AR Iskandar, C Mathis, WK Schlage, S Frentzel, P Leroy, Y Xiang, ...
Toxicology in vitro 39, 29-51, 2017
632017
Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: a comparison of mono-culture and coculture model containing fibroblasts
AR Iskandar, Y Xiang, S Frentzel, M Talikka, P Leroy, D Kuehn, E Guedj, ...
Toxicological Sciences 147 (1), 207-221, 2015
612015
Systems toxicology assessment of the biological impact of a candidate modified risk tobacco product on human organotypic oral epithelial cultures
F Zanetti, A Sewer, C Mathis, AR Iskandar, R Kostadinova, WK Schlage, ...
Chemical research in toxicology 29 (8), 1252-1269, 2016
602016
Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties
SS Weber, KP Kaminski, JL Perret, P Leroy, A Mazurov, MC Peitsch, ...
Food and Chemical Toxicology 132, 110660, 2019
562019
A six-month systems toxicology inhalation/cessation study in ApoE−/− mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP …
B Phillips, J Szostak, B Titz, WK Schlage, E Guedj, P Leroy, G Vuillaume, ...
Food and chemical toxicology 126, 113-141, 2019
482019
Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day …
F Zanetti, B Titz, A Sewer, GL Sasso, E Scotti, WK Schlage, C Mathis, ...
Food and chemical toxicology 101, 15-35, 2017
442017
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague–Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology
B Phillips, M Esposito, J Verbeeck, S Boué, A Iskandar, G Vuillaume, ...
Inhalation toxicology 27 (9), 405-431, 2015
432015
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke
J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ...
American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020
402020
Alterations in serum polyunsaturated fatty acids and eicosanoids in patients with mild to moderate chronic obstructive pulmonary disease (COPD)
B Titz, K Luettich, P Leroy, S Boue, G Vuillaume, T Vihervaara, K Ekroos, ...
International journal of molecular sciences 17 (9), 1583, 2016
392016
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version …
BW Phillips, WK Schlage, B Titz, U Kogel, D Sciuscio, F Martin, P Leroy, ...
Food and chemical toxicology 116, 388-413, 2018
372018
Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke
B Titz, J Szostak, A Sewer, B Phillips, C Nury, T Schneider, S Dijon, ...
Computational and Structural Biotechnology Journal 18, 1056-1073, 2020
342020
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