Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation JD Neuhaus, SM Morrow, M Brunavs, MC Willis Organic letters 18 (7), 1562-1565, 2016 | 53 | 2016 |
Synthesis of 6/7-halotetralones WM Owton, M Brunavs Synthetic communications 21 (8-9), 981-987, 1991 | 25 | 1991 |
Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data Set LR Vidler, IA Watson, BJ Margolis, DJ Cummins, M Brunavs ACS medicinal chemistry letters 9 (8), 792-796, 2018 | 23 | 2018 |
European Patent Appl. EP 557075 M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith Chem. Abstr 120, 106768t, 1994 | 21 | 1994 |
High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor SR Baker, J Boot, M Brunavs, D Dobson, R Green, L Hayhurst, M Keenan, ... Bioorganic & medicinal chemistry letters 15 (21), 4727-4730, 2005 | 19 | 2005 |
Direct fluorination of the anthraquinone nucleus: scope and application to the synthesis of novel rhein analogues M Brunavs, CP Dell, WM Owton Journal of fluorine chemistry 68 (2), 201-203, 1994 | 18 | 1994 |
An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors E Jambrina, R Cerne, E Smith, L Scampavia, M Cuadrado, J Findlay, ... Journal of biomolecular screening 21 (5), 468-479, 2016 | 14 | 2016 |
Synthesis of 6-tert-Butyl-2-Arylpyridines MW Owton, PT Gallagher, M Brunavs Synthetic communications 22 (3), 351-357, 1992 | 13 | 1992 |
Pharmaceutical compounds M Brunavs, CP Dell, DR Dobson, PT Gallagher, TA Hicks, WM Owton, ... US Patent 5,480,873, 1996 | 11 | 1996 |
Recent disclosures of clinical candidates (SMR award lecture) M Brunavs, P Cowley, SE Ward, P Weber Drugs of the Future 38 (3), 127-133, 2013 | 9 | 2013 |
CA 120: 106768 M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith EP Patent 557,075, 1993 | 8 | 1993 |
4H-Naphtho [1, 2-b] pyran cell antiproliferation agents M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith European Patent EP 557, 25, 1994 | 6 | 1994 |
Therapy for diabetic complications M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith US Patent 5,378,717, 1995 | 5 | 1995 |
Methods of using dihydropyrans M Brunavs, CP Dell, PT Gallagher, WM Owton, JP Singh, CW Smith US Patent 5,378,699, 1995 | 5 | 1995 |
Pharmaceutical compounds M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith US Patent 5,663,375, 1997 | 4 | 1997 |
Anthraquinones related to rhein inhibit glucose uptake into chondrocytes. A mechanism for anti-osteoarthritis drugs? SL Carney, RJ Broadmore, R Tomlinson, A Kingston, PT Gallagher, ... Bioorganic & Medicinal Chemistry Letters 7 (7), 817-822, 1997 | 4 | 1997 |
Partnerships: Future models for drug discovery. Highlights from the Society for Medicines. Research Symposium held on June 20th 2013 at The Lilly Research Laboratories, Manor … GJ Macdonald, M Brunavs, PV Fish, SE Ward Drugs of the Future 38 (9), 649-654, 2013 | 2 | 2013 |
5, 6-dihydronaphtho [1, 2-b] pyrans and their use as pharmaceutical compounds M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith US Patent 5,622,987, 1997 | 2 | 1997 |
5-[4-(azetidin-3-yloxy)-phenyl]-2-phenyl-5H-thiazolo [5, 4-C] pyridin-4-one derivatives and their use as MCH receptor antagonists KM Gardinier, DJ Garmene, EJ Hembre, M Brunavs, HJ Szekeres US Patent 8,049,013, 2011 | | 2011 |
Investigating the behavior of published PAINS alerts using a phar-maceutical company dataset: Supporting Information LR Vidler, IA Watson, BJ Margolis, DJ Cummins, M Brunavs | | |