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Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation
JD Neuhaus, SM Morrow, M Brunavs, MC Willis
Organic letters 18 (7), 1562-1565, 2016
532016
Synthesis of 6/7-halotetralones
WM Owton, M Brunavs
Synthetic communications 21 (8-9), 981-987, 1991
251991
Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data Set
LR Vidler, IA Watson, BJ Margolis, DJ Cummins, M Brunavs
ACS medicinal chemistry letters 9 (8), 792-796, 2018
232018
European Patent Appl. EP 557075
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
Chem. Abstr 120, 106768t, 1994
211994
High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor
SR Baker, J Boot, M Brunavs, D Dobson, R Green, L Hayhurst, M Keenan, ...
Bioorganic & medicinal chemistry letters 15 (21), 4727-4730, 2005
192005
Direct fluorination of the anthraquinone nucleus: scope and application to the synthesis of novel rhein analogues
M Brunavs, CP Dell, WM Owton
Journal of fluorine chemistry 68 (2), 201-203, 1994
181994
An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors
E Jambrina, R Cerne, E Smith, L Scampavia, M Cuadrado, J Findlay, ...
Journal of biomolecular screening 21 (5), 468-479, 2016
142016
Synthesis of 6-tert-Butyl-2-Arylpyridines
MW Owton, PT Gallagher, M Brunavs
Synthetic communications 22 (3), 351-357, 1992
131992
Pharmaceutical compounds
M Brunavs, CP Dell, DR Dobson, PT Gallagher, TA Hicks, WM Owton, ...
US Patent 5,480,873, 1996
111996
Recent disclosures of clinical candidates (SMR award lecture)
M Brunavs, P Cowley, SE Ward, P Weber
Drugs of the Future 38 (3), 127-133, 2013
92013
CA 120: 106768
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
EP Patent 557,075, 1993
81993
4H-Naphtho [1, 2-b] pyran cell antiproliferation agents
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
European Patent EP 557, 25, 1994
61994
Therapy for diabetic complications
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
US Patent 5,378,717, 1995
51995
Methods of using dihydropyrans
M Brunavs, CP Dell, PT Gallagher, WM Owton, JP Singh, CW Smith
US Patent 5,378,699, 1995
51995
Pharmaceutical compounds
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
US Patent 5,663,375, 1997
41997
Anthraquinones related to rhein inhibit glucose uptake into chondrocytes. A mechanism for anti-osteoarthritis drugs?
SL Carney, RJ Broadmore, R Tomlinson, A Kingston, PT Gallagher, ...
Bioorganic & Medicinal Chemistry Letters 7 (7), 817-822, 1997
41997
Partnerships: Future models for drug discovery. Highlights from the Society for Medicines. Research Symposium held on June 20th 2013 at The Lilly Research Laboratories, Manor …
GJ Macdonald, M Brunavs, PV Fish, SE Ward
Drugs of the Future 38 (9), 649-654, 2013
22013
5, 6-dihydronaphtho [1, 2-b] pyrans and their use as pharmaceutical compounds
M Brunavs, CP Dell, PT Gallagher, WM Owton, CW Smith
US Patent 5,622,987, 1997
21997
5-[4-(azetidin-3-yloxy)-phenyl]-2-phenyl-5H-thiazolo [5, 4-C] pyridin-4-one derivatives and their use as MCH receptor antagonists
KM Gardinier, DJ Garmene, EJ Hembre, M Brunavs, HJ Szekeres
US Patent 8,049,013, 2011
2011
Investigating the behavior of published PAINS alerts using a phar-maceutical company dataset: Supporting Information
LR Vidler, IA Watson, BJ Margolis, DJ Cummins, M Brunavs
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