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MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells Q Ji, X Hao, M Zhang, W Tang, M Yang, L Li, D Xiang, JT DeSano, ... PLoS One 4 (8), e6816, 2009 | 857 | 2009 |
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres Q Ji, X Hao, Y Meng, M Zhang, J DeSano, D Fan, L Xu BMC cancer 8 (1), 1-12, 2008 | 531 | 2008 |
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three … Z Nikolovska-Coleska, L Xu, Z Hu, Y Tomita, P Li, PP Roller, R Wang, ... Journal of medicinal chemistry 47 (10), 2430-2440, 2004 | 476 | 2004 |
Bcl-2: Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch RT Marquez, L Xu American journal of cancer research 2 (2), 214, 2012 | 474 | 2012 |
Systemic Tumor-targeted Gene Delivery by Anti-Transferrin Receptor scFv-Immunoliposomes L Xu, CC Huang, W Huang, WH Tang, A Rait, YZ Yin, I Cruz, LM Xiang, ... Molecular cancer therapeutics 1 (5), 337-346, 2002 | 355 | 2002 |
Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts L Xu, KF Pirollo, WH Tang, A Rait, EH Chang Human gene therapy 10 (18), 2941-2952, 1999 | 283 | 1999 |
Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa Y Meng, W Tang, Y Dai, X Wu, M Liu, Q Ji, M Ji, K Pienta, T Lawrence, ... Molecular cancer therapeutics 7 (7), 2192-2202, 2008 | 225 | 2008 |
MicroRNA regulation of cancer stem cells and therapeutic implications JT DeSano, L Xu The AAPS journal 11 (4), 682-692, 2009 | 210 | 2009 |
(−)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer L Xu, D Yang, S Wang, W Tang, M Liu, M Davis, J Chen, JM Rae, ... Molecular cancer therapeutics 4 (2), 197-205, 2005 | 203 | 2005 |
Structure-based design of potent, conformationally constrained Smac mimetics H Sun, Z Nikolovska-Coleska, CY Yang, L Xu, M Liu, Y Tomita, H Pan, ... Journal of the American Chemical Society 126 (51), 16686-16687, 2004 | 200 | 2004 |
A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum J Lian, X Wu, F He, D Karnak, W Tang, Y Meng, D Xiang, M Ji, ... Cell Death & Differentiation 18 (1), 60-71, 2011 | 194 | 2011 |
Systemic p53 gene therapy of cancer with immunolipoplexes targeted by anti-transferrin receptor scFv L Xu, WH Tang, CC Huang, W Alexander, LM Xiang, KF Pirollo, A Rait, ... Molecular Medicine 7 (10), 723-734, 2001 | 193 | 2001 |
Tumor-targeted p53-gene therapy enhances the efficacy of conventional chemo/radiotherapy L Xu, KF Pirollo, EH Chang Journal of controlled release 74 (1), 115-128, 2001 | 189 | 2001 |
Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked … H Sun, Z Nikolovska-Coleska, CY Yang, L Xu, Y Tomita, K Krajewski, ... Journal of medicinal chemistry 47 (17), 4147-4150, 2004 | 187 | 2004 |
Self-assembly of a virus-mimicking nanostructure system for efficient tumor-targeted gene delivery L Xu, P Frederik, KF Pirollo, WH Tang, A Rait, LM Xiang, W Huang, I Cruz, ... Human gene therapy 13 (3), 469-481, 2002 | 175 | 2002 |
Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice L Li, X Hao, J Qin, W Tang, F He, A Smith, M Zhang, DM Simeone, ... Gastroenterology 146 (4), 1108-1118. e12, 2014 | 157 | 2014 |
Identification and validation of novel small molecule disruptors of HuR-mRNA interaction X Wu, L Lan, DM Wilson, RT Marquez, W Tsao, P Gao, A Roy, BA Turner, ... ACS chemical biology 10 (6), 1476-1484, 2015 | 149 | 2015 |
Transferrin-liposome-mediated p53 sensitization of squamous cell carcinoma of the head and neck to radiation in vitro L Xu, KF Pirollo, EH Chang Human gene therapy 8 (4), 467-475, 1997 | 147 | 1997 |