GSVA: gene set variation analysis for microarray and RNA-seq data S Hänzelmann, R Castelo, J Guinney BMC bioinformatics 14, 1-15, 2013 | 9792 | 2013 |
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes T Mahdi, S Hänzelmann, A Salehi, SJ Muhammed, TM Reinbothe, Y Tang, ... Cell metabolism 16 (5), 625-633, 2012 | 207 | 2012 |
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation M Kalwa, S Hänzelmann, S Otto, CC Kuo, J Franzen, S Joussen, ... Nucleic acids research 44 (22), 10631-10643, 2016 | 161 | 2016 |
Detection of RNA–DNA binding sites in long noncoding RNAs CC Kuo, S Hänzelmann, N Sentürk Cetin, S Frank, B Zajzon, JP Derks, ... Nucleic acids research 47 (6), e32-e32, 2019 | 151 | 2019 |
Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites S Hänzelmann, F Beier, EG Gusmao, CM Koch, S Hummel, I Charapitsa, ... Clinical epigenetics 7, 1-15, 2015 | 78 | 2015 |
Epigenetic program and transcription factor circuitry of dendritic cell development Q Lin, H Chauvistré, IG Costa, EG Gusmao, S Mitzka, S Hänzelmann, ... Nucleic acids research 43 (20), 9680-9693, 2015 | 65 | 2015 |
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia L Bastian, MP Schroeder, C Eckert, C Schlee, JO Tanchez, S Kämpf, ... Leukemia 33 (8), 1895-1909, 2019 | 60 | 2019 |
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes AS Axelsson, T Mahdi, HA Nenonen, T Singh, S Hänzelmann, A Wendt, ... Nature communications 8 (1), 15652, 2017 | 40 | 2017 |
Mtss1 is a critical epigenetically regulated tumor suppressor in CML M Schemionek, O Herrmann, MM Reher, N Chatain, C Schubert, IG Costa, ... Leukemia 30 (4), 823-832, 2016 | 38 | 2016 |
CDKN2A loss and PIK3CA mutation in myoepithelial‐like metaplastic breast cancer S Bartels, JL van Luttikhuizen, M Christgen, L Mägel, A Luft, ... The Journal of Pathology 245 (3), 373-383, 2018 | 32 | 2018 |
The propagation of perturbations in rewired bacterial gene networks R Baumstark, S Hänzelmann, S Tsuru, Y Schaerli, M Francesconi, ... Nature communications 6 (1), 10105, 2015 | 27 | 2015 |
Thrombin stimulates insulin secretion via protease-activated receptor-3 S Hänzelmann, J Wang, E Güney, Y Tang, E Zhang, AS Axelsson, ... Islets 7 (4), e1118195, 2015 | 23 | 2015 |
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment L Bastian, AM Hartmann, T Beder, S Hänzelmann, J Kässens, ... Leukemia 36 (6), 1676-1680, 2022 | 19 | 2022 |
DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection F Hausmann, C Ergen, R Khatri, M Marouf, S Hänzelmann, N Gagliani, ... Genome Biology 24 (1), 212, 2023 | 7 | 2023 |
Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML) S Steinhäuser, P Silva, L Lenk, T Beder, A Hartmann, S Hänzelmann, ... Leukemia 37 (1), 134-142, 2023 | 6 | 2023 |
A prognostic neural epigenetic signature in high-grade glioma R Drexler, R Khatri, T Sauvigny, M Mohme, CL Maire, A Ryba, Y Zghaibeh, ... Nature Medicine, 1-14, 2024 | 5 | 2024 |
Kidney outcome after mild to moderate COVID-19 C Schmidt-Lauber, S Hänzelmann, S Schunk, EL Petersen, A Alabdo, ... Nephrology Dialysis Transplantation 38 (9), 2031-2040, 2023 | 5 | 2023 |
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation J Lázaro-Navarro, HJ Pimentel-Gutiérrez, A Gauert, AIH Hagemann, ... Blood Advances 5 (24), 5501-5506, 2021 | 5 | 2021 |
Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS working group study VHJ van der Velden, M Brüggemann, G Cazzaniga, B Scheijen, B Tops, ... Leukemia 35 (3), 924-928, 2021 | 5 | 2021 |
Triplex domain finder: Detection of triple helix binding domains in long non-coding rnas S Hänzelmann, CC Kuo, M Kalwa, W Wagner, IG Costa bioRxiv, 020297, 2015 | 5 | 2015 |