Roland Brandt
Roland Brandt
Professor of Neurobiology, University of Osnabrück
Verified email at - Homepage
Cited by
Cited by
Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain.
R Brandt, J Léger, G Lee
The Journal of cell biology 131 (5), 1327-1340, 1995
CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
A Martin-Villalba, I Herr, I Jeremias, M Hahne, R Brandt, J Vogel, ...
Journal of Neuroscience 19 (10), 3809-3817, 1999
Molecular interactions among protein phosphatase 2A, tau, and microtubules: implications for the regulation of tau phosphorylation and the development of tauopathies
E Sontag, V Nunbhakdi-Craig, G Lee, R Brandt, C Kamibayashi, J Kuret, ...
Journal of Biological Chemistry 274 (36), 25490-25498, 1999
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
R Brandt, M Hundelt, N Shahani
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1739 (2-3 …, 2005
Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau
C Klein, EM Krämer, AM Cardine, B Schraven, R Brandt, J Trotter
Journal of Neuroscience 22 (3), 698-707, 2002
Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro.
R Brandt, G Lee
Journal of Biological Chemistry 268 (5), 3414-3419, 1993
Tau binds to the distal axon early in development of polarity in a microtubule-and microfilament-dependent manner
M Kempf, A Clement, A Faissner, G Lee, R Brandt
Journal of Neuroscience 16 (18), 5583-5592, 1996
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
T Fath, J Eidenmüller, R Brandt
Journal of Neuroscience 22 (22), 9733-9741, 2002
Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
T Maas, J Eidenmüller, R Brandt
Journal of Biological Chemistry 275 (21), 15733-15740, 2000
Functions and malfunctions of the tau proteins
N Shahani, R Brandt
Cellular and Molecular Life Sciences CMLS 59, 1668-1680, 2002
Tau biology and tau-directed therapies for Alzheimer’s disease
L Bakota, R Brandt
Drugs 76 (3), 301-313, 2016
Divergent pathways mediate spine alterations and cell death induced by amyloid-β, wild-type tau, and R406W tau
C Tackenberg, R Brandt
Journal of Neuroscience 29 (46), 14439-14450, 2009
Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons
D Janning, M Igaev, F Sündermann, J Brühmann, O Beutel, JJ Heinisch, ...
Molecular biology of the cell 25 (22), 3541-3551, 2014
Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
J Eidenmüller, T Fath, T Maas, M Pool, E Sontag, R Brandt
Biochemical Journal 357 (3), 759-767, 2001
Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau
J Léger, M Kempf, G Lee, R Brandt
Journal of Biological Chemistry 272 (13), 8441-8446, 1997
The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner
A Gauthier-Kemper, C Weissmann, N Golovyashkina, Z Sebö-Lemke, ...
Journal of Cell Biology 192 (4), 647-661, 2011
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss
C Tackenberg, S Grinschgl, A Trutzel, AC Santuccione, MC Frey, ...
Cell death & disease 4 (4), e608-e608, 2013
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins
J Eidenmüller, T Fath, A Hellwig, J Reed, E Sontag, R Brandt
Biochemistry 39 (43), 13166-13175, 2000
Differential effect of phosphorylation and substrate modulation on tau's ability to promote microtubule growth and nucleation.
R Brandt, G Lee, DB Teplow, D Shalloway, M Abdel-Ghany
Journal of Biological Chemistry 269 (16), 11776-11782, 1994
A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau
R Brandt, A Gergou, I Wacker, T Fath, H Hutter
Neurobiology of aging 30 (1), 22-33, 2009
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