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Haitao Mark Ji
Haitao Mark Ji
Associate Member, H. Lee Moffitt Cancer Center & Research Center
Bestätigte E-Mail-Adresse bei moffitt.org - Startseite
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Zitiert von
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A three-dimensional model of lanosterol 14α-demethylase of Candida albicans and its interaction with azole antifungals
H Ji, W Zhang, Y Zhou, M Zhang, J Zhu, Y Song, J Lü, J Zhu
Journal of medicinal chemistry 43 (13), 2493-2505, 2000
3182000
Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking
C Sheng, W Zhang, H Ji, M Zhang, Y Song, H Xu, J Zhu, Z Miao, Q Jiang, ...
Journal of medicinal chemistry 49 (8), 2512-2525, 2006
2102006
Hot spot-based design of small-molecule inhibitors for protein–protein interactions
W Guo, JA Wisniewski, H Ji
Bioorganic & medicinal chemistry letters 24 (11), 2546-2554, 2014
1682014
Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14α-demethylase of fungi
H Ji, W Zhang, M Zhang, M Kudo, Y Aoyama, Y Yoshida, C Sheng, ...
Journal of medicinal chemistry 46 (4), 474-485, 2003
1592003
Three-Dimensional Model of Lanosterol 14α-Demethylase from Cryptococcus neoformans: Active-Site Characterization and Insights into Azole Binding
C Sheng, Z Miao, H Ji, J Yao, W Wang, X Che, G Dong, J Lü, W Guo, ...
Antimicrobial agents and chemotherapy 53 (8), 3487-3495, 2009
1262009
Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase …
H Ji, BZ Stanton, J Igarashi, H Li, P Martásek, LJ Roman, TL Poulos, ...
Journal of the American Chemical Society 130 (12), 3900-3914, 2008
1182008
Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping
H Ji, H Li, P Martásek, LJ Roman, TL Poulos, RB Silverman
Journal of medicinal chemistry 52 (3), 779-797, 2009
1022009
Direct α-heteroarylation of amides (α to nitrogen) and ethers through a benzaldehyde-mediated photoredox reaction
Y Zhang, KB Teuscher, H Ji
Chemical Science 7 (3), 2111-2118, 2016
992016
Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy
H Ji, S Tan, J Igarashi, H Li, M Derrick, P Martásek, LJ Roman, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
942009
Homology modeling of lanosterol 14α-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate interactions
C Sheng, W Zhang, M Zhang, Y Song, H Ji, J Zhu, J Yao, J Yu, S Yang, ...
Journal of Biomolecular Structure and Dynamics 22 (1), 91-99, 2004
832004
Computer modeling of selective regions in the active site of nitric oxide synthases: implication for the design of isoform-selective inhibitors
H Ji, H Li, M Flinspach, TL Poulos, RB Silverman
Journal of Medicinal Chemistry 46 (26), 5700-5711, 2003
832003
Inhibition of β-catenin/B cell lymphoma 9 protein− protein interaction using α-helix–mimicking sulfono-γ-AApeptide inhibitors
P Sang, M Zhang, Y Shi, C Li, S Abdulkadir, Q Li, H Ji, J Cai
Proceedings of the National Academy of Sciences 116 (22), 10757-10762, 2019
802019
Direct targeting of β‐catenin in the Wnt signaling pathway: Current progress and perspectives
Z Wang, Z Li, H Ji
Medicinal research reviews 41 (4), 2109-2129, 2021
782021
Selective neuronal nitric oxide synthase inhibitors
EP Erdal, EA Litzinger, J Seo, Y Zhu, H Ji, RB Silverman
Current topics in medicinal chemistry 5 (7), 603-624, 2005
732005
New azoles with potent antifungal activity: design, synthesis and molecular docking
X Che, C Sheng, W Wang, Y Cao, Y Xu, H Ji, G Dong, Z Miao, J Yao, ...
European journal of medicinal chemistry 44 (10), 4218-4226, 2009
722009
Rational design of selective small-molecule inhibitors for β-catenin/B-cell lymphoma 9 protein–protein interactions
LR Hoggard, Y Zhang, M Zhang, V Panic, JA Wisniewski, H Ji
Journal of the American Chemical Society 137 (38), 12249-12260, 2015
702015
Synthesis and antifungal activities of novel 2-aminotetralin derivatives
B Yao, H Ji, Y Cao, Y Zhou, J Zhu, J Lü, Y Li, J Chen, C Zheng, Y Jiang, ...
Journal of medicinal chemistry 50 (22), 5293-5300, 2007
682007
Design, synthesis and antifungal activity of isosteric analogues of benzoheterocyclic N-myristoyltransferase inhibitors
C Sheng, H Xu, W Wang, Y Cao, G Dong, S Wang, X Che, H Ji, Z Miao, ...
European journal of medicinal chemistry 45 (9), 3531-3540, 2010
672010
Discovery of selective small-molecule inhibitors for the β-Catenin/T-Cell factor protein–protein interaction through the optimization of the acyl hydrazone moiety
JL Catrow, Y Zhang, M Zhang, H Ji
Journal of medicinal chemistry 58 (11), 4678-4692, 2015
652015
Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives
H Ji, SL Delker, H Li, P Martásek, LJ Roman, TL Poulos, RB Silverman
Journal of medicinal chemistry 53 (21), 7804-7824, 2010
642010
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