| Engineered antibody fragments and the rise of single domains P Holliger, PJ Hudson Nature biotechnology 23 (9), 1126-1136, 2005 | 2633 | 2005 |
| " Diabodies": small bivalent and bispecific antibody fragments. P Holliger, T Prospero, G Winter Proceedings of the National Academy of Sciences 90 (14), 6444-6448, 1993 | 2235 | 1993 |
| Human anti‐self antibodies with high specificity from phage display libraries. AD Griffiths, M Malmqvist, JD Marks, JM Bye, MJ Embleton, J McCafferty, ... The EMBO journal 12 (2), 725-734, 1993 | 929 | 1993 |
| Synthetic genetic polymers capable of heredity and evolution VB Pinheiro, AI Taylor, C Cozens, M Abramov, M Renders, S Zhang, ... Science 336 (6079), 341-344, 2012 | 766 | 2012 |
| Directed evolution of polymerase function by compartmentalized self-replication FJ Ghadessy, JL Ong, P Holliger Proceedings of the National Academy of Sciences 98 (8), 4552-4557, 2001 | 593 | 2001 |
| Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain NM Low, P Holliger, G Winter Journal of molecular biology 260 (3), 359-368, 1996 | 518 | 1996 |
| Ribozyme-catalyzed transcription of an active ribozyme A Wochner, J Attwater, A Coulson, P Holliger science 332 (6026), 209-212, 2011 | 445 | 2011 |
| The C-terminal domain of TolA is the coreceptor for filamentous phage infection of E. coli L Riechmann, P Holliger Cell 90 (2), 351-360, 1997 | 315 | 1997 |
| In-ice evolution of RNA polymerase ribozyme activity J Attwater, A Wochner, P Holliger Nature chemistry 5 (12), 1011-1018, 2013 | 295 | 2013 |
| Catalysts from synthetic genetic polymers AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ... Nature 518 (7539), 427-430, 2015 | 288 | 2015 |
| Crystal structure of a diabody, a bivalent antibody fragment O Perisic, PA Webb, P Holliger, G Winter, RL Williams Structure 2 (12), 1217-1226, 1994 | 255 | 1994 |
| Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution FJ Ghadessy, N Ramsay, F Boudsocq, D Loakes, A Brown, S Iwai, ... Nature biotechnology 22 (6), 755-759, 2004 | 237 | 2004 |
| The XNA world: progress towards replication and evolution of synthetic genetic polymers VB Pinheiro, P Holliger Current opinion in chemical biology 16 (3-4), 245-252, 2012 | 201 | 2012 |
| Ice as a protocellular medium for RNA replication J Attwater, A Wochner, VB Pinheiro, A Coulson, P Holliger Nature Communications 1 (1), 76, 2010 | 169 | 2010 |
| Engineering bispecific antibodies P Holliger, G Winter Current opinion in biotechnology 4 (4), 446-449, 1993 | 157 | 1993 |
| Directed evolution of DNA polymerase, RNA polymerase and reverse transcriptase activity in a single polypeptide JL Ong, D Loakes, S Jaroslawski, K Too, P Holliger Journal of molecular biology 361 (3), 537-550, 2006 | 153 | 2006 |
| Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody P Holliger, J Brissinck, RL Williams, K Thielemans, G Winter Protein Engineering, Design and Selection 9 (3), 299-305, 1996 | 152 | 1996 |
| Molecular breeding of polymerases for amplification of ancient DNA M d'Abbadie, M Hofreiter, A Vaisman, D Loakes, D Gasparutto, J Cadet, ... Nature biotechnology 25 (8), 939-943, 2007 | 150 | 2007 |
| Crystal structure of the two N-terminal domains of g3p from filamentous phage fd at 1.9 Å: evidence for conformational lability P Holliger, L Riechmann, RL Williams Journal of molecular biology 288 (4), 649-657, 1999 | 149 | 1999 |
| Towards XNA nanotechnology: new materials from synthetic genetic polymers VB Pinheiro, P Holliger Trends in biotechnology 32 (6), 321-328, 2014 | 144 | 2014 |
