Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ... Nature medicine 22 (6), 586-597, 2016 | 1171 | 2016 |
Microglial control of astrocytes in response to microbial metabolites V Rothhammer, DM Borucki, EC Tjon, MC Takenaka, CC Chao, ... Nature 557 (7707), 724-728, 2018 | 824 | 2018 |
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ... Nature neuroscience 22 (5), 729-740, 2019 | 377 | 2019 |
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation V Rothhammer, JE Kenison, E Tjon, MC Takenaka, KA de Lima, ... Proceedings of the National Academy of Sciences 114 (8), 2012-2017, 2017 | 184 | 2017 |
Environmental control of astrocyte pathogenic activities in CNS inflammation MA Wheeler, M Jaronen, R Covacu, SEJ Zandee, G Scalisi, ... Cell 176 (3), 581-596. e18, 2019 | 166 | 2019 |
Barcoded viral tracing of single-cell interactions in central nervous system inflammation IC Clark, C Gutiérrez-Vázquez, MA Wheeler, Z Li, V Rothhammer, ... Science 372 (6540), eabf1230, 2021 | 155 | 2021 |
Metabolic control of astrocyte pathogenic activity via cPLA2-MAVS CC Chao, C Gutiérrez-Vázquez, V Rothhammer, L Mayo, MA Wheeler, ... Cell 179 (7), 1483-1498. e22, 2019 | 141 | 2019 |
Zebrafish as a Model Host for Candida albicans Infection CC Chao, PC Hsu, CF Jen, IH Chen, CH Wang, HC Chan, PW Tsai, ... Infection and immunity 78 (6), 2512-2521, 2010 | 127 | 2010 |
Role of sphingolipid metabolism in neurodegeneration M Alaamery, N Albesher, N Aljawini, M Alsuwailm, S Massadeh, ... Journal of neurochemistry 158 (1), 25-35, 2021 | 74 | 2021 |
Identification of environmental factors that promote intestinal inflammation LM Sanmarco, CC Chao, YC Wang, JE Kenison, Z Li, JM Rone, ... Nature 611 (7937), 801-809, 2022 | 51 | 2022 |
System-wide analysis of the T cell response R Covacu, H Philip, M Jaronen, J Almeida, JE Kenison, S Darko, ... Cell reports 14 (11), 2733-2744, 2016 | 44 | 2016 |
Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction study YY Chen, CC Chao, FC Liu, PC Hsu, HF Chen, SC Peng, YJ Chuang, ... PLoS One 8 (9), e72483, 2013 | 43 | 2013 |
Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFα-induced inflammatory responses SK Yang, YC Wang, CC Chao, YJ Chuang, CY Lan, BS Chen BMC medical genomics 3, 1-19, 2010 | 41 | 2010 |
Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in … SC Peng, DSH Wong, KC Tung, YY Chen, CC Chao, CH Peng, ... BMC bioinformatics 11, 1-13, 2010 | 38 | 2010 |
Identification of infection-and defense-related genes via a dynamic host-pathogen interaction network using a Candida albicans-zebrafish infection model ZY Kuo, YJ Chuang, CC Chao, FC Liu, CY Lan, BS Chen Journal of innate immunity 5 (2), 137-152, 2013 | 29 | 2013 |
Aryl hydrocarbon receptor activation in astrocytes by laquinimod ameliorates autoimmune inflammation in the CNS V Rothhammer, JE Kenison, Z Li, E Tjon, MC Takenaka, CC Chao, ... Neurology: Neuroimmunology & Neuroinflammation 8 (2), e946, 2021 | 28 | 2021 |
A genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation CC Kang, YJ Chuang, KC Tung, CC Chao, CY Tang, SC Peng, ... BMC bioinformatics 12, 1-8, 2011 | 28 | 2011 |
Diverse Hap43-independent functions of the Candida albicans CCAAT-binding complex PC Hsu, CC Chao, CY Yang, YL Ye, FC Liu, YJ Chuang, CY Lan Eukaryotic cell 12 (6), 804-815, 2013 | 20 | 2013 |
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells LM Sanmarco, JM Rone, CM Polonio, G Fernandez Lahore, F Giovannoni, ... Nature 620 (7975), 881-889, 2023 | 19 | 2023 |
Engineered bacteria producing aryl‐hydrocarbon receptor agonists protect against ethanol‐induced liver disease in mice T Kouno, S Zeng, Y Wang, Y Duan, S Lang, B Gao, P Hartmann, N Cabré, ... Alcohol: Clinical and Experimental Research 47 (5), 856-867, 2023 | 10 | 2023 |