| Hedgehog signaling in glioblastoma multiforme S Braun, H Oppermann, A Mueller, C Renner, A Hovhannisyan, ... Cancer biology & therapy 13 (7), 487-495, 2012 | 55 | 2012 |
| Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner VI Bunik, G Mkrtchyan, A Grabarska, H Oppermann, D Daloso, WL Araujo, ... Oncotarget 7 (18), 26400, 2016 | 47 | 2016 |
| Mitochondrial impairment may increase cellular NAD (P) H: resazurin oxidoreductase activity, perturbing the NAD (P) H-based viability assays VA Aleshin, AV Artiukhov, H Oppermann, AV Kazantsev, NV Lukashev, ... Cells 4 (3), 427-451, 2015 | 47 | 2015 |
| The Chk1 inhibitor SAR-020106 sensitizes human glioblastoma cells to irradiation, to temozolomide, and to decitabine treatment I Patties, S Kallendrusch, L Böhme, E Kendzia, H Oppermann, F Gaunitz, ... Journal of Experimental & Clinical Cancer Research 38, 1-16, 2019 | 35 | 2019 |
| The antineoplastic effect of carnosine is accompanied by induction of PDK4 and can be mimicked by l-histidine U Letzien, H Oppermann, J Meixensberger, F Gaunitz Amino acids 46, 1009-1019, 2014 | 33 | 2014 |
| Dual Luciferase Assay for Secreted Luciferases Based on Gaussia and NanoLuc K Heise, H Oppermann, J Meixensberger, R Gebhardt, F Gaunitz Assay and drug development technologies 11 (4), 244-252, 2013 | 30 | 2013 |
| The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells H Oppermann, M Heinrich, C Birkemeyer, J Meixensberger, F Gaunitz Amino Acids 51 (7), 999-1008, 2019 | 28 | 2019 |
| Exome first approach to reduce diagnostic costs and time–retrospective analysis of 111 individuals with rare neurodevelopmental disorders J Klau, R Abou Jamra, M Radtke, H Oppermann, JR Lemke, S Beblo, ... European Journal of Human Genetics 30 (1), 117-125, 2022 | 27 | 2022 |
| Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS H Oppermann, Y Ding, J Sharma, M Berndt Paetz, J Meixensberger, ... Nutrition & metabolism 13, 1-11, 2016 | 26 | 2016 |
| Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells VI Bunik, A Artiukhov, A Kazantsev, R Goncalves, D Daloso, ... Oncotarget 6 (37), 40036, 2015 | 25 | 2015 |
| Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling H Oppermann, H Faust, U Yamanishi, J Meixensberger, F Gaunitz PLoS One 14 (6), e0218972, 2019 | 23 | 2019 |
| Pyruvate attenuates the anti-neoplastic effect of carnosine independently from oxidative phosphorylation H Oppermann, L Schnabel, J Meixensberger, F Gaunitz Oncotarget 7 (52), 85848, 2016 | 21 | 2016 |
| d,l-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro H Oppermann, M Matusova, A Glasow, J Dietterle, R Baran-Schmidt, ... Cancer Chemotherapy and Pharmacology 83, 1017-1024, 2019 | 18 | 2019 |
| Carnosine influences transcription via epigenetic regulation as demonstrated by enhanced histone acetylation of the pyruvate dehydrogenase kinase 4 promoter in glioblastoma cells H Oppermann, A Alvanos, C Seidel, J Meixensberger, F Gaunitz Amino acids 51, 61-71, 2019 | 18 | 2019 |
| Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts H Oppermann, J Dietterle, K Purcz, M Morawski, C Eisenlöffel, W Müller, ... Cancer cell international 18, 1-10, 2018 | 18 | 2018 |
| Analysis of cellular and molecular antitumor effects upon inhibition of SATB1 in glioblastoma cells A Frömberg, M Rabe, H Oppermann, F Gaunitz, A Aigner BMC cancer 17, 1-11, 2017 | 15 | 2017 |
| Erythrocytes prevent degradation of carnosine by human serum carnosinase H Oppermann, S Elsel, C Birkemeyer, J Meixensberger, F Gaunitz International journal of molecular sciences 22 (23), 12802, 2021 | 14 | 2021 |
| De novo variants in ATP2B1 lead to neurodevelopmental delay MJ Rahimi, N Urban, M Wegler, H Sticht, M Schaefer, B Popp, F Gaunitz, ... The American Journal of Human Genetics 109 (5), 944-952, 2022 | 13 | 2022 |
| Carnosine’s inhibitory effect on glioblastoma cell growth is independent of its cleavage H Oppermann, K Purcz, C Birkemeyer, R Baran-Schmidt, ... Amino Acids 51, 761-772, 2019 | 13 | 2019 |
| The clinical and molecular spectrum of QRICH1 associated neurodevelopmental disorder S Kumble, AM Levy, J Punetha, H Gao, N Ah Mew, K Anyane‐Yeboa, ... Human mutation 43 (2), 266-282, 2022 | 12 | 2022 |
