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Johannes Karges
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Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy
F Heinemann, J Karges, G Gasser
Accounts of chemical research 50 (11), 2727-2736, 2017
5292017
Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges
Angewandte Chemie International Edition 61 (5), e202112236, 2022
1932022
Rationally designed ruthenium complexes for 1-and 2-photon photodynamic therapy
J Karges, S Kuang, F Maschietto, O Blacque, I Ciofini, H Chao, G Gasser
Nature communications 11 (1), 3262, 2020
1922020
A Multi‐action and Multi‐target RuII–PtIV Conjugate Combining Cancer‐Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers
J Karges, T Yempala, M Tharaud, D Gibson, G Gasser
Angewandte Chemie International Edition 59 (18), 7069-7075, 2020
1692020
Rationally designed long-wavelength absorbing Ru (II) polypyridyl complexes as photosensitizers for photodynamic therapy
J Karges, F Heinemann, M Jakubaszek, F Maschietto, C Subecz, M Dotou, ...
Journal of the American Chemical Society 142 (14), 6578-6587, 2020
1512020
Photo‐Reduction with NIR Light of Nucleus‐Targeting PtIV Nanoparticles for Combined Tumor‐Targeted Chemotherapy and Photodynamic Immunotherapy
D Wei, Y Huang, B Wang, L Ma, J Karges, H Xiao
Angewandte Chemie International Edition 61 (20), e202201486, 2022
1072022
Polymeric encapsulation of novel homoleptic bis (dipyrrinato) zinc (II) complexes with long lifetimes for applications as photodynamic therapy photosensitisers
J Karges, U Basu, O Blacque, H Chao, G Gasser
Angewandte Chemie 131 (40), 14472-14478, 2019
1012019
Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia
S Kuang, F Wei, J Karges, L Ke, K Xiong, X Liao, G Gasser, L Ji, H Chao
Journal of the American Chemical Society 144 (9), 4091-4101, 2022
962022
Cancer cell membrane camouflaged iridium complexes functionalized black-titanium nanoparticles for hierarchical-targeted synergistic NIR-II photothermal and sonodynamic therapy
J Shen, J Karges, K Xiong, Y Chen, L Ji, H Chao
Biomaterials 275, 120979, 2021
872021
Metal complexes for therapeutic applications
J Karges, RW Stokes, SM Cohen
Trends in Chemistry 3 (7), 523-534, 2021
862021
A Biodegradable Iridium (III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway
L Ke, F Wei, L Xie, J Karges, Y Chen, L Ji, H Chao
Angewandte Chemie International Edition 61 (28), e202205429, 2022
782022
Mesoporous silica nanoparticles functionalised with a photoactive ruthenium (II) complex: Exploring the formulation of a metal-based photodynamic therapy photosensitiser
Y Ellahioui, M Patra, C Mari, R Kaabi, J Karges, G Gasser, S Gómez-Ruiz
Dalton Transactions 48 (18), 5940-5951, 2019
672019
Immunogenic cell death inducing metal complexes for cancer therapy
L Zhang, N Montesdeoca, J Karges, H Xiao
Angewandte Chemie International Edition 62 (21), e202300662, 2023
602023
ReI Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS‐CoV‐2 Main Cysteine Protease
J Karges, M Kalaj, M Gembicky, SM Cohen
Angewandte Chemie International Edition 60 (19), 10716-10723, 2021
572021
Metal complexes as antiviral agents for SARS‐CoV‐2
J Karges, SM Cohen
ChemBioChem 22 (16), 2600-2607, 2021
522021
Systematic investigation of the antiproliferative activity of a series of ruthenium terpyridine complexes
J Karges, O Blacque, M Jakubaszek, B Goud, P Goldner, G Gasser
Journal of inorganic biochemistry 198, 110752, 2019
512019
Polymeric encapsulation of a ruthenium polypyridine complex for tumor targeted one-and two-photon photodynamic therapy
J Karges, J Li, L Zeng, H Chao, G Gasser
ACS Applied Materials & Interfaces 12 (49), 54433-54444, 2020
492020
A Ru (II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers
J Karges, F Heinemann, F Maschietto, M Patra, O Blacque, I Ciofini, ...
Bioorganic & medicinal chemistry 27 (12), 2666-2675, 2019
452019
Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PLpro
M Gil‐Moles, S Türck, U Basu, A Pettenuzzo, S Bhattacharya, A Rajan, ...
Chemistry–A European Journal 27 (71), 17928-17940, 2021
432021
Ruthenium-initiated polymerization of lactide: A route to remarkable cellular uptake for photodynamic therapy of cancer
N Soliman, LK McKenzie, J Karges, E Bertrand, M Tharaud, ...
Chemical Science 11 (10), 2657-2663, 2020
422020
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