| Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile MC Rea, CS Sit, E Clayton, PM O'Connor, RM Whittal, J Zheng, ... Proceedings of the National Academy of Sciences 107 (20), 9352-9357, 2010 | 613 | 2010 |
| Lassomycin, a ribosomally synthesized cyclic peptide, kills Mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2 E Gavrish, CS Sit, S Cao, O Kandror, A Spoering, A Peoples, L Ling, ... Chemistry & biology 21 (4), 509-518, 2014 | 421 | 2014 |
| The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against Gram-negative bacteria in combination with EDTA treatment LA Martin-Visscher, S Yoganathan, CS Sit, CT Lohans, JC Vederas FEMS microbiology letters 317 (2), 152-159, 2011 | 130 | 2011 |
| Selvamicin, an atypical antifungal polyene from two alternative genomic contexts EB Van Arnam, AC Ruzzini, CS Sit, H Horn, AA Pinto-Tomás, CR Currie, ... Proceedings of the National Academy of Sciences 113 (46), 12940-12945, 2016 | 126 | 2016 |
| Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants CS Sit, AC Ruzzini, EB Van Arnam, TR Ramadhar, CR Currie, J Clardy Proceedings of the National Academy of Sciences 112 (43), 13150-13154, 2015 | 109 | 2015 |
| Biosynthesis of aminovinyl-cysteine-containing peptides and its application in the production of potential drug candidates CS Sit, S Yoganathan, JC Vederas Accounts of chemical research 44 (4), 261-268, 2011 | 99 | 2011 |
| Isolation of a variant of subtilosin A with hemolytic activity T Huang, H Geng, VR Miyyapuram, CS Sit, JC Vederas, MM Nakano Journal of bacteriology 191 (18), 5690-5696, 2009 | 85 | 2009 |
| The 3D solution structure of thurincin H, a bacteriocin with four sulfur to α‐carbon crosslinks CS Sit, MJ van Belkum, RT McKay, RW Worobo, JC Vederas Angewandte Chemie 123 (37), 8877-8880, 2011 | 83 | 2011 |
| Approaches to the discovery of new antibacterial agents based on bacteriocins CS Sit, JC Vederas Biochemistry and Cell Biology 86 (2), 116-123, 2008 | 73 | 2008 |
| Biochemical, Structural, and Genetic Characterization of Tridecaptin A1, an Antagonist of Campylobacter jejuni CT Lohans, MJ van Belkum, SA Cochrane, Z Huang, CS Sit, LM McMullen, ... ChemBioChem 15 (2), 243-249, 2014 | 71 | 2014 |
| Chemical synthesis and biological evaluation of gallidermin-siderophore conjugates S Yoganathan, CS Sit, JC Vederas Organic & biomolecular chemistry 9 (7), 2133-2141, 2011 | 70 | 2011 |
| The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to α-carbon cross-links CS Sit, RT McKay, C Hill, RP Ross, JC Vederas Journal of the American Chemical Society 133 (20), 7680-7683, 2011 | 66 | 2011 |
| The Saccharomyces cerevisiae succinate dehydrogenase does not require heme for ubiquinone reduction KS Oyedotun, CS Sit, BD Lemire Biochimica et Biophysica Acta (BBA)-Bioenergetics 1767 (12), 1436-1445, 2007 | 65 | 2007 |
| Electrochemical surface-enhanced Raman spectroscopy as a platform for bacterial detection and identification TP Lynk, CS Sit, CL Brosseau Analytical chemistry 90 (21), 12639-12646, 2018 | 64 | 2018 |
| Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy CT Lohans, Z Huang, MJ van Belkum, M Giroud, CS Sit, EM Steels, ... Journal of the American Chemical Society 134 (48), 19540-19543, 2012 | 64 | 2012 |
| Total chemical synthesis of lassomycin and lassomycin-amide S Lear, T Munshi, AS Hudson, C Hatton, J Clardy, JA Mosely, TJ Bull, ... Organic & biomolecular chemistry 14 (19), 4534-4541, 2016 | 59 | 2016 |
| A rebeccamycin analog provides plasmid-encoded niche defense EB Van Arnam, AC Ruzzini, CS Sit, CR Currie, J Clardy Journal of the American Chemical Society 137 (45), 14272-14274, 2015 | 57 | 2015 |
| Insights into the mechanism of action of the two-peptide lantibiotic lacticin 3147 A Bakhtiary, SA Cochrane, P Mercier, RT McKay, M Miskolzie, CS Sit, ... Journal of the American Chemical Society 139 (49), 17803-17810, 2017 | 55 | 2017 |
| Response of methicillin-resistant Staphylococcus aureus to amicoumacin A A Lama, J Pané-Farré, T Chon, AM Wiersma, CS Sit, JC Vederas, ... PLoS One 7 (3), e34037, 2012 | 36 | 2012 |
| Substitution of a Conserved Disulfide in the Type IIa Bacteriocin, Leucocin A, with L‐Leucine and L‐Serine Residues: Effects on Activity and Three‐Dimensional … CS Sit, CT Lohans, MJ van Belkum, CD Campbell, M Miskolzie, ... ChemBioChem 13 (1), 35-38, 2012 | 26 | 2012 |
Jon ClardyProfessor of Biological Chemistry, Harvard Medical SchoolVerified email at hms.harvard.edu
