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Joshy George
Joshy George
Director, Computational Sciences, Jackson Laboratory for Genomic Medicine, Connecticut
Bestätigte E-Mail-Adresse bei jax.org
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Zitiert von
Zitiert von
Jahr
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
YH Loh, Q Wu, JL Chew, VB Vega, W Zhang, X Chen, G Bourque, ...
Nature genetics 38 (4), 431-440, 2006
30082006
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
23382020
Pan-cancer analysis of whole genomes
I TCGA-Consortium
Nature 578 (7793), 82-93, 2020
1672*2020
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
RW Tothill, AV Tinker, J George, R Brown, SB Fox, S Lade, DS Johnson, ...
Clinical cancer research 14 (16), 5198-5208, 2008
15202008
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
LD Miller, J Smeds, J George, VB Vega, L Vergara, A Ploner, Y Pawitan, ...
Proceedings of the National Academy of Sciences 102 (38), 13550-13555, 2005
14892005
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
14672015
BRCA mutation frequency and patterns of treatment response in BRCA mutation–positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group
K Alsop, S Fereday, C Meldrum, A DeFazio, C Emmanuel, J George, ...
Journal of clinical oncology 30 (21), 2654, 2012
13742012
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
8352020
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
AV Ivshina, J George, O Senko, B Mow, TC Putti, J Smeds, T Lindahl, ...
Cancer research 66 (21), 10292-10301, 2006
8302006
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
6762020
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
YH Loh, W Zhang, X Chen, J George, HH Ng
Genes & development 21 (20), 2545-2557, 2007
6052007
Whole-genome cartography of estrogen receptor α binding sites
CY Lin, VB Vega, JS Thomsen, T Zhang, SL Kong, M Xie, KP Chiu, ...
PLoS genetics 3 (6), e87, 2007
5402007
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature genetics 52 (3), 331-341, 2020
5262020
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
4972020
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
N Lawlor, J George, M Bolisetty, R Kursawe, L Sun, V Sivakamasundari, ...
Genome research 27 (2), 208-222, 2017
4582017
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
W Sieh, M Köbel, TA Longacre, DD Bowtell, A DeFazio, MT Goodman, ...
The lancet oncology 14 (9), 853-862, 2013
4522013
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene
X Zhang, J George, S Deb, JL Degoutin, EA Takano, SB Fox, DDL Bowtell, ...
Oncogene 30 (25), 2810-2822, 2011
3472011
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas
D Etemadmoghadam, A Defazio, R Beroukhim, C Mermel, J George, ...
Clinical cancer research 15 (4), 1417-1427, 2009
3252009
The landscape of viral associations in human cancers
M Zapatka, I Borozan, DS Brewer, M Iskar, A Grundhoff, M Alawi, N Desai, ...
Nature genetics 52 (3), 320-330, 2020
3182020
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
3092020
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