Optimized localization analysis for single-molecule tracking and super-resolution microscopy KI Mortensen, LS Churchman, JA Spudich, H Flyvbjerg Nature methods 7 (5), 377-381, 2010 | 1011 | 2010 |
Nascent transcript sequencing visualizes transcription at nucleotide resolution LS Churchman, JS Weissman Nature 469 (7330), 368-373, 2011 | 907 | 2011 |
Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms O Padovan-Merhar, GP Nair, AG Biaesch, A Mayer, S Scarfone, SW Foley, ... Molecular cell 58 (2), 339-352, 2015 | 468 | 2015 |
The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain KM Harlen, LS Churchman Nature reviews Molecular cell biology 18 (4), 263-273, 2017 | 458 | 2017 |
Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time LS Churchman, Z Ökten, RS Rock, JF Dawson, JA Spudich Proceedings of the National Academy of Sciences 102 (5), 1419-1423, 2005 | 422 | 2005 |
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ... Molecular cell 67 (1), 5-18. e19, 2017 | 391 | 2017 |
Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution A Mayer, J Di Iulio, S Maleri, U Eser, J Vierstra, A Reynolds, R Sandstrom, ... Cell 161 (3), 541-554, 2015 | 368 | 2015 |
Synchronized mitochondrial and cytosolic translation programs MT Couvillion, IC Soto, G Shipkovenska, LS Churchman Nature 533 (7604), 499-503, 2016 | 318 | 2016 |
Splicing kinetics and coordination revealed by direct nascent RNA sequencing through nanopores HL Drexler, K Choquet, LS Churchman Molecular cell 77 (5), 985-998. e8, 2020 | 176 | 2020 |
Comprehensive RNA polymerase II interactomes reveal distinct and varied roles for each phospho-CTD residue KM Harlen, KL Trotta, EE Smith, MM Mosaheb, SM Fuchs, LS Churchman Cell reports 15 (10), 2147-2158, 2016 | 158 | 2016 |
Myosin VI walks hand-over-hand along actin Z Ökten, LS Churchman, RS Rock, JA Spudich Nature structural & molecular biology 11 (9), 884-887, 2004 | 157 | 2004 |
Pause & go: from the discovery of RNA polymerase pausing to its functional implications A Mayer, HM Landry, LS Churchman Current opinion in cell biology 46, 72-80, 2017 | 141 | 2017 |
Rapid creation and quantitative monitoring of high coverage shRNA libraries MC Bassik, RJ Lebbink, LS Churchman, NT Ingolia, W Patena, ... Nature methods 6 (6), 443-445, 2009 | 134 | 2009 |
A chromatin-based mechanism for limiting divergent noncoding transcription S Marquardt, R Escalante-Chong, N Pho, J Wang, LS Churchman, ... Cell 157 (7), 1712-1723, 2014 | 124 | 2014 |
Single-molecule regulatory architectures captured by chromatin fiber sequencing AB Stergachis, BM Debo, E Haugen, LS Churchman, ... Science 368 (6498), 1449-1454, 2020 | 110 | 2020 |
Native elongating transcript sequencing (NETseq) LS Churchman, JS Weissman Current protocols in molecular biology 98 (1), 14.4. 1-14.4. 17, 2012 | 107 | 2012 |
Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness BW Tye, N Commins, LV Ryazanova, M Wühr, M Springer, D Pincus, ... elife 8, e43002, 2019 | 105 | 2019 |
A non-Gaussian distribution quantifies distances measured with fluorescence localization techniques LS Churchman, H Flyvbjerg, JA Spudich Biophysical journal 90 (2), 668-671, 2006 | 98 | 2006 |
H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway N Terzi, LS Churchman, L Vasiljeva, J Weissman, S Buratowski Molecular and cellular biology 31 (17), 3569-3583, 2011 | 87 | 2011 |
The ground state and evolution of promoter region directionality Y Jin, U Eser, K Struhl, LS Churchman Cell 170 (5), 889-898. e10, 2017 | 86 | 2017 |