C. David James
C. David James
Professor of Neurological Surgery & Scientific Director of the Malnati Brain Tumor Institute
Verified email at northwestern.edu - Homepage
Cited by
Cited by
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
RG Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ...
Cancer Cell 17 (1), 98-110, 2010
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
J Silber, DA Lim, C Petritsch, AI Persson, AK Maunakea, M Yu, ...
BMC medicine 6 (1), 14, 2008
Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo
AJ Ekstrand, CD James, WK Cavenee, B Seliger, RF Pettersson, ...
Cancer research 51 (8), 2164-2172, 1991
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
L Frederick, XY Wang, G Eley, CD James
Cancer research 60 (5), 1383-1387, 2000
Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p.
J Reifenberger, G Reifenberger, L Liu, CD James, W Wechsler, ...
The American journal of pathology 145 (5), 1175, 1994
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N-and/or C-terminal tails.
AJ Ekstrand, N Sugawa, CD James, VP Collins
Proceedings of the National Academy of Sciences 89 (10), 4309-4313, 1992
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
JS Smith, I Tachibana, SM Passe, BK Huntley, TJ Borell, N Iturria, ...
Journal of the National Cancer Institute 93 (16), 1246-1256, 2001
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.
N Sugawa, AJ Ekstrand, CD James, VP Collins
Proceedings of the National Academy of Sciences 87 (21), 8602-8606, 1990
Clonal genomic alterations in glioma malignancy stages
CD James, E Carlbom, JP Dumanski, M Hansen, M Nordenskjold, ...
Cancer research 48 (19), 5546-5551, 1988
Sporadic medulloblastomas contain PTCH mutations
C Raffel, RB Jenkins, L Frederick, D Hebrink, B Alderete, DW Fults, ...
Cancer research 57 (5), 842-845, 1997
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
R Chen, MC Nishimura, SM Bumbaca, S Kharbanda, WF Forrest, ...
Cancer cell 17 (4), 362-375, 2010
Mutational inactivation of STAG2 causes aneuploidy in human cancer
DA Solomon, T Kim, LA Diaz-Martinez, J Fair, AG Elkahloun, BT Harris, ...
Science 333 (6045), 1039-1043, 2011
The histone H3. 3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
KM Chan, D Fang, H Gan, R Hashizume, C Yu, M Schroeder, N Gupta, ...
Genes & development 27 (9), 985-990, 2013
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
A Lai, S Kharbanda, WB Pope, A Tran, OE Solis, F Peale, WF Forrest, ...
Journal of clinical oncology 29 (34), 4482, 2011
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma
MD Prados, SM Chang, N Butowski, R DeBoer, R Parvataneni, H Carliner, ...
Journal of Clinical Oncology 27 (4), 579, 2009
Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations
W Liu, DI Smith, KJ Rechtzigel, SN Thibodeau, CD James
Nucleic acids research 26 (6), 1396-1400, 1998
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
CE Pelloski, KV Ballman, AF Furth, L Zhang, E Lin, EP Sulman, K Bhat, ...
Journal of Clinical Oncology 25 (16), 2288-2294, 2007
Mitotic recombination of chromosome 17 in astrocytomas
CD James, E Carlbom, M Nordenskjold, VP Collins, WK Cavenee
Proceedings of the National Academy of Sciences 86 (8), 2858-2862, 1989
Mechanisms of chemoresistance to alkylating agents in malignant glioma
JN Sarkaria, GJ Kitange, CD James, R Plummer, H Calvert, M Weller, ...
Clinical cancer research 14 (10), 2900-2908, 2008
Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification.
AJ Ekstrand, N Longo, ML Hamid, JJ Olson, L Liu, VP Collins, CD James
Oncogene 9 (8), 2313-2320, 1994
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