Follow
Richard N. McLaughlin Jr.
Richard N. McLaughlin Jr.
Pacific Northwest Research Institute
Verified email at pnri.org - Homepage
Title
Cited by
Cited by
Year
The spatial architecture of protein function and adaptation
RN McLaughlin Jr, FJ Poelwijk, A Raman, WS Gosal, R Ranganathan
Nature 491 (7422), 138-142, 2012
5172012
Hot spots for allosteric regulation on protein surfaces
KA Reynolds, RN McLaughlin, R Ranganathan
Cell 147 (7), 1564-1575, 2011
3762011
Genetic conflicts: the usual suspects and beyond
RN McLaughlin Jr, HS Malik
Journal of Experimental Biology 220 (1), 6-17, 2017
1472017
Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates
L Yang, M Emerman, HS Malik, RN McLaughlin
Elife 9, e58436, 2020
342020
Conservation and innovation of APOBEC3A restriction functions during primate evolution
RN McLaughlin Jr, JT Gable, CJ Wittkopp, M Emerman, HS Malik
Molecular biology and evolution 33 (8), 1889-1901, 2016
272016
Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency
RN McLaughlin Jr, JM Young, L Yang, R Neme, HA Wichman, HS Malik
PLOS Genetics 10 (9), e1004531, 2014
272014
Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner
A Sharma, RN McLaughlin Jr, RS Basom, C Kikawa, M OhAinle, JS Yount, ...
PLoS pathogens 15 (7), e1007925, 2019
132019
Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
R Colón-Thillet, E Hsieh, L Graf, RN McLaughlin Jr, JM Young, G Kochs, ...
PLoS biology 17 (10), e3000181, 2019
122019
Characterization of LINE-1 transposons in a human genome at allelic resolution
L Yang, GA Metzger, RN McLaughlin Jr
bioRxiv, 594200, 2019
62019
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo
L Zhang, Y Wang, Y Dong, A Pant, Y Liu, L Masserman, Y Xu, ...
Developmental cell 57 (6), 750-766. e5, 2022
42022
The functional impact of 1,570 SNP-accessible missense variants in human OTC
RS Lo, GA Cromie, M Tang, K Teng, K Owens, A Sirr, JN Kutz, ...
bioRxiv, 2022.10. 26.513893, 2022
32022
LINE-1 Retroelements Get ZAPped!
RN McLaughlin Jr, HS Malik
PLoS Genetics 11 (7), e1005364, 2015
32015
Predicting the functional effect of compound heterozygous genotypes from large scale variant effect maps
MJ Xie, GA Cromie, K Owens, MS Timour, M Tang, JN Kutz, AW El-Hattab, ...
bioRxiv, 2023.01. 11.523651, 2023
22023
Nanopore sequencing of 1000 Genomes Project samples to build a comprehensive catalog of human genetic variation
JA Gustafson, SB Gibson, N Damaraju, MPG Zalusky, K Hoekzema, ...
medRxiv, 2024.03. 05.24303792, 2024
12024
Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology
RN McLaughlin Jr
PLoS Biology 16 (3), e2005470, 2018
12018
Evolutionary insights from profiling LINE-1 activity at allelic resolution in a single human genome
L Yang, GA Metzger, R Padilla Del Valle, D Delgadillo Rubalcaba, ...
The EMBO Journal 43 (1), 112-131, 2024
2024
Constructing and interpreting a large-scale variant effect map for an ultrarare disease gene: Comprehensive prediction of the functional impact of PSAT1 genotypes
MJ Xie, GA Cromie, K Owens, MS Timour, M Tang, JN Kutz, AW El-Hattab, ...
PLoS Genetics 19 (10), e1010972, 2023
2023
Stealing genes and facing consequences
RP Del Valle, RN McLaughlin Jr
Science 378 (6618), 356-357, 2022
2022
A Global Experimental Analysis of Protein Function: A Case Study in the PDZ Domain
RN McLaughlin Jr
2011
The system can't perform the operation now. Try again later.
Articles 1–19