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Bruck Taddese
Bruck Taddese
Novartis
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Jahr
Five computational developability guidelines for therapeutic antibody profiling
MIJ Raybould, C Marks, K Krawczyk, B Taddese, J Nowak, AP Lewis, ...
Proceedings of the National Academy of Sciences, 201810576, 2019
2632019
Thera-SAbDab: the Therapeutic Structural Antibody Database
MIJ Raybould, C Marks, AP Lewis, J Shi, A Bujotzek, B Taddese, ...
Nucleic Acids Research 48 (D1), D383-D388, 2020
1052020
Do plants contain g protein-coupled receptors?
B Taddese, GJG Upton, GR Bailey, SRD Jordan, NY Abdulla, PJ Reeves, ...
Plant physiology 164 (1), 287-307, 2014
852014
Bioinformatics and molecular modelling approaches to GPCR oligomerization
LM Simpson, B Taddese, ID Wall, CA Reynolds
Current opinion in pharmacology 10 (1), 30-37, 2010
742010
DLAB-Deep learning methods for structure-based virtual screening of antibodies
C Schneider, A Buchanan, B Taddese, CM Deane
bioRxiv, 2021
652021
Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
S Vohra, B Taddese, AC Conner, DR Poyner, DL Hay, J Barwell, ...
Journal of The Royal Society Interface 10 (79), 20120846, 2013
592013
Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain
WA Williams, JE Linley, CA Jones, Y Shibata, A Snijder, J Button, ...
Pain 160 (9), 1989-2003, 2019
422019
Ab-Ligity: Identifying sequence-dissimilar antibodies that bind to the same epitope
WK Wong, SA Robinson, A Bujotzek, G Georges, AP Lewis, J Shi, ...
BioRxiv, 2020
362020
The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach
MJ Woolley, HA Watkins, B Taddese, ZG Karakullukcu, J Barwell, ...
Journal of The Royal Society Interface 10 (88), 20130589, 2013
362013
SCALOP: sequence-based antibody canonical loop structure annotation
WK Wong, G Georges, F Ros, S Kelm, AP Lewis, B Taddese, J Leem, ...
Bioinformatics, 2018
252018
Evolution of chemokine receptors is driven by mutations in the sodium binding site
B Taddese, M Deniaud, A Garnier, A Tiss, H Guissouma, H Abdi, ...
PLoS computational biology 14 (6), e1006209, 2018
212018
The activation of the CGRP receptor
J Barwell, M Wheatley, AC Conner, B Taddese, S Vohra, CA Reynolds, ...
Biochemical Society Transactions 41 (1), 180-184, 2013
212013
Modeling active GPCR conformations
B Taddese, LM Simpson, ID Wall, FE Blaney, CA Reynolds
Methods in enzymology 522, 21-35, 2013
182013
G-protein-coupled receptor dynamics: dimerization and activation models compared with experiment
B Taddese, LM Simpson, ID Wall, FE Blaney, NJ Kidley, HSX Clark, ...
Biochemical Society Transactions 40 (2), 394-399, 2012
172012
Molecular insights into the transmembrane domain of the thyrotropin receptor
V Chantreau, B Taddese, M Munier, L Gourdin, D Henrion, P Rodien, ...
PloS one 10 (11), e0142250, 2015
152015
Deciphering collaborative sidechain motions in proteins during molecular dynamics simulations
B Taddese, A Garnier, H Abdi, D Henrion, M Chabbert
Scientific reports 10 (1), 1-14, 2020
92020
E-Biothon: an experimental platform for BioInformatics
M Daydé, B Depardon, A Franc, JF Gibrat, R Guilllier, Y Karami, F Sutter, ...
2015 Computer Science and Information Technologies (CSIT), 1-4, 2015
62015
Bios2cor: an R package integrating dynamic and evolutionary correlations to identify functionally important residues in proteins
B Taddese, A Garnier, M Deniaud, D Henrion, M Chabbert
Bioinformatics, 2021
52021
Identifying subset errors in multiple sequence alignments
A Roy, B Taddese, S Vohra, PK Thimmaraju, CJR Illingworth, ...
Journal of Biomolecular Structure and Dynamics 32 (3), 364-371, 2014
52014
Co-Variation Approaches to the Evolution of Protein Families
J Pelé, B Taddese, M Deniaud, A Garnier, D Henrion
Adv Tech Biol Med 5 (250), 2379-1764.1000250, 2017
32017
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