| Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum JI MacRae, MWA Dixon, MK Dearnley, HH Chua, JM Chambers, S Kenny, ... BMC biology 11, 1-10, 2013 | 267 | 2013 |
| Multivalent small-molecule pan-RAS inhibitors ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ... Cell 168 (5), 878-889. e29, 2017 | 259 | 2017 |
| Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism EC Saunders, WW Ng, J Kloehn, JM Chambers, M Ng, MJ McConville PLoS pathogens 10 (1), e1003888, 2014 | 178 | 2014 |
| Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase JM Chambers, PA Hill, JA Aaron, Z Han, DW Christianson, NN Kuzma, ... journal of the american chemical society 131 (2), 563-569, 2009 | 167 | 2009 |
| Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis … EC Saunders, WW Ng, JM Chambers, M Ng, T Naderer, JO Krömer, ... Journal of Biological Chemistry 286 (31), 27706-27717, 2011 | 103 | 2011 |
| Structure of a 129Xe-Cryptophane Biosensor Complexed with Human Carbonic Anhydrase II JA Aaron, JM Chambers, KM Jude, L Di Costanzo, IJ Dmochowski, ... Journal of the American Chemical Society 130 (22), 6942-6943, 2008 | 78 | 2008 |
| Synthesis of biotinylated episilvestrol: highly selective targeting of the translation factors eIF4AI/II JM Chambers, LM Lindqvist, A Webb, DCS Huang, GP Savage, ... Organic letters 15 (6), 1406-1409, 2013 | 70 | 2013 |
| Protein–ligand binding free energy calculations with FEP+ L Wang, J Chambers, R Abel Biomolecular simulations: methods and protocols, 201-232, 2019 | 56 | 2019 |
| Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor LM Lindqvist, I Vikström, JM Chambers, K McArthur, M Ann Anderson, ... Cell death & disease 3 (10), e409-e409, 2012 | 49 | 2012 |
| Benchmarking refined and unrefined AlphaFold2 structures for hit discovery Y Zhang, M Vass, D Shi, E Abualrous, JM Chambers, N Chopra, C Higgs, ... Journal of Chemical Information and Modeling 63 (6), 1656-1667, 2023 | 46 | 2023 |
| K-RasG12D Has a Potential Allosteric Small Molecule Binding Site H Feng, Y Zhang, PH Bos, JM Chambers, MM Dupont, BR Stockwell Biochemistry 58 (21), 2542-2554, 2019 | 36 | 2019 |
| Simplified silvestrol analogues with potent cytotoxic activity BC Hawkins, LM Lindqvist, D Nhu, PP Sharp, D Segal, AK Powell, ... ChemMedChem 9 (7), 1556-1566, 2014 | 24 | 2014 |
| Total synthesis of 2‴, 5‴-diepisilvestrol and its C1‴ epimer: key structure activity relationships at C1‴ and C2‴ JM Chambers, DCS Huang, LM Lindqvist, GP Savage, JM White, ... Journal of natural products 75 (8), 1500-1504, 2012 | 23 | 2012 |
| Use of 13C Stable Isotope Labelling for Pathway and Metabolic Flux Analysis in Leishmania Parasites EC Saunders, DP de Souza, JM Chambers, M Ng, J Pyke, MJ McConville Parasite Genomics Protocols, 281-296, 2015 | 17 | 2015 |
| In Biomolecular Simulations: Methods and Protocols; Bonomi M., Camilloni C., Eds L Wang, J Chambers, R Abel Springer: New York, NY, 2019 | 13 | 2019 |
| Biomolecular Simulations L Wang, J Chambers, R Abel Methods in Molecular Biology 2022, 201-232, 2019 | 10 | 2019 |
| Total synthesis of a biotinylated rocaglate: Selective targeting of the translation factors eIF4AI/II JM Chambers, LM Lindqvist, GP Savage, MA Rizzacasa Bioorganic & medicinal chemistry letters 26 (2), 262-264, 2016 | 9 | 2016 |
| Tri-functionalized cryptophane biosensors I Dmochowski, AP Hill, Q Wei, JM Chambers US Patent 8,222,022, 2012 | 5 | 2012 |
| Tri-functionalized cryptophane biosensors I Dmochowski, AP Hill, Q Wei, JM Chambers US Patent 8,222,022, 2012 | 5 | 2012 |
| Water networks and correlated motions in mutant isocitrate dehydrogenase 1 (IDH1) are critical for allosteric inhibitor binding and activity JM Chambers, W Miller, G Quichocho, V Upadhye, DA Matteo, AA Bobkov, ... Biochemistry 59 (4), 479-490, 2019 | 3 | 2019 |
Malcolm McconvilleUniversity of MelbourneBestätigte E-Mail-Adresse bei unimelb.edu.au
