Metabolic network structure determines key aspects of functionality and regulation J Stelling, S Klamt, K Bettenbrock, S Schuster, ED Gilles Nature 420 (6912), 190-193, 2002 | 918 | 2002 |
Structural and functional analysis of cellular networks with CellNetAnalyzer S Klamt, J Saez-Rodriguez, ED Gilles BMC systems biology 1 (1), 1-13, 2007 | 562 | 2007 |
Comparison of network-based pathway analysis methods JA Papin, J Stelling, ND Price, S Klamt, S Schuster, BO Palsson Trends in biotechnology 22 (8), 400-405, 2004 | 461 | 2004 |
A methodology for the structural and functional analysis of signaling and regulatory networks S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles BMC bioinformatics 7 (1), 1-26, 2006 | 435 | 2006 |
Hypergraphs and cellular networks S Klamt, UU Haus, F Theis PLoS Comput Biol 5 (5), e1000385, 2009 | 373 | 2009 |
Two approaches for metabolic pathway analysis? S Klamt, J Stelling Trends in biotechnology 21 (2), 64-69, 2003 | 353 | 2003 |
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ... Molecular systems biology 5 (1), 331, 2009 | 342 | 2009 |
A logical model provides insights into T cell receptor signaling J Saez-Rodriguez, L Simeoni, JA Lindquist, R Hemenway, U Bommhardt, ... PLoS Comput Biol 3 (8), e163, 2007 | 342 | 2007 |
Computation of elementary modes: a unifying framework and the new binary approach J Gagneur, S Klamt BMC bioinformatics 5 (1), 1-21, 2004 | 320 | 2004 |
Minimal cut sets in biochemical reaction networks S Klamt, ED Gilles Bioinformatics 20 (2), 226-234, 2004 | 311 | 2004 |
Combinatorial complexity of pathway analysis in metabolic networks S Klamt, J Stelling Molecular biology reports 29 (1), 233-236, 2002 | 282 | 2002 |
FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps S Klamt, J Stelling, M Ginkel, ED Gilles Bioinformatics 19 (2), 261-269, 2003 | 276 | 2003 |
GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism DJV Beste, T Hooper, G Stewart, B Bonde, C Avignone-Rossa, ... Genome biology 8 (5), 1-18, 2007 | 229 | 2007 |
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling DM Wittmann, J Krumsiek, J Saez-Rodriguez, DA Lauffenburger, S Klamt, ... BMC systems biology 3 (1), 1-21, 2009 | 220 | 2009 |
The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data R Samaga, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, S Klamt PLoS Comput Biol 5 (8), e1000438, 2009 | 211 | 2009 |
Calculability analysis in underdetermined metabolic networks illustrated by a model of the central metabolism in purple nonsulfur bacteria S Klamt, S Schuster, ED Gilles Biotechnology and Bioengineering 77 (7), 734-751, 2002 | 148 | 2002 |
Generalized concept of minimal cut sets in biochemical networks S Klamt Biosystems 83 (2-3), 233-247, 2006 | 142 | 2006 |
SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools C Chaouiya, D Bérenguier, SM Keating, A Naldi, MP Van Iersel, ... BMC systems biology 7 (1), 1-15, 2013 | 127 | 2013 |
Enumeration of smallest intervention strategies in genome-scale metabolic networks A von Kamp, S Klamt PLoS Comput Biol 10 (1), e1003378, 2014 | 112 | 2014 |
Computing complex metabolic intervention strategies using constrained minimal cut sets O Hädicke, S Klamt Metabolic engineering 13 (2), 204-213, 2011 | 112 | 2011 |