TRPV1: on the road to pain relief A Jara-Oseguera, SA Simon, T Rosenbaum Current molecular pharmacology 1 (3), 255-269, 2008 | 247 | 2008 |
A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic H Salazar, I Llorente, A Jara-Oseguera, R García-Villegas, M Munari, ... Nature neuroscience 11 (3), 255-261, 2008 | 237 | 2008 |
Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site A Nieto-Posadas, G Picazo-Juárez, I Llorente, A Jara-Oseguera, ... Nature chemical biology 8 (1), 78-85, 2012 | 217 | 2012 |
Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel G Picazo-Juarez, S Romero-Suarez, A Nieto-Posadas, I Llorente, ... Journal of Biological Chemistry 286 (28), 24966-24976, 2011 | 143 | 2011 |
Structural determinants of gating in the TRPV1 channel H Salazar, A Jara-Oseguera, E Hernandez-Garcia, I Llorente, ... Nature structural & molecular biology 16 (7), 704-710, 2009 | 116 | 2009 |
Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin C Bae, C Anselmi, J Kalia, A Jara-Oseguera, CD Schwieters, D Krepkiy, ... Elife 5, e11273, 2016 | 84 | 2016 |
Heat activation is intrinsic to the pore domain of TRPV1 F Zhang, A Jara-Oseguera, TH Chang, C Bae, SM Hanson, KJ Swartz Proceedings of the National Academy of Sciences 115 (2), E317-E324, 2018 | 77 | 2018 |
The role of allosteric coupling on thermal activation of thermo-TRP channels A Jara-Oseguera, LD Islas Biophysical journal 104 (10), 2160-2169, 2013 | 76 | 2013 |
An external sodium ion binding site controls allosteric gating in TRPV1 channels A Jara-Oseguera, C Bae, KJ Swartz Elife 5, e13356, 2016 | 60 | 2016 |
Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms KE Huffer, AA Aleksandrova, A Jara-Oseguera, LR Forrest, KJ Swartz Elife 9, e58660, 2020 | 52 | 2020 |
Engineering vanilloid-sensitivity into the rat TRPV2 channel F Zhang, SM Hanson, A Jara-Oseguera, D Krepkiy, C Bae, LV Pearce, ... Elife 5, e16409, 2016 | 52 | 2016 |
TRP channel gating physiology A Nieto-Posadas, A Jara-Oseguera, T Rosenbaum Current topics in medicinal chemistry 11 (17), 2131-2150, 2011 | 51 | 2011 |
Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums A Jara-Oseguera, I Llorente, T Rosenbaum, LD Islas The Journal of general physiology 132 (5), 547-562, 2008 | 48 | 2008 |
The ion selectivity filter is not an activation gate in TRPV1-3 channels A Jara-Oseguera, KE Huffer, KJ Swartz Elife 8, e51212, 2019 | 40 | 2019 |
Uncoupling charge movement from channel opening in voltage-gated potassium channels by ruthenium complexes A Jara-Oseguera, IG Ishida, GE Rangel-Yescas, N Espinosa-Jalapa, ... Journal of Biological Chemistry 286 (18), 16414-16425, 2011 | 35 | 2011 |
Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity F Zhang, K Swartz, A Jara-Oseguera Biophysical Journal 116 (3), 535a, 2019 | 28 | 2019 |
Molecular mechanisms of TRPV1 channel activation A Jara-Oseguera, A Nieto-Posadas, A Szallasi, LD Islas, T Rosenbaum The Open Pain Journal 3 (1), 2010 | 26 | 2010 |
El canal TRPV1 como diana para tratar el dolor H Salazar, A Jara Oseguera, T Rosenbaum Rev. neurol.(Ed. impr.), 357-364, 2009 | 21 | 2009 |
The TRPV1 channel as a target for the treatment of pain H Salazar, A Jara-Oseguera, T Rosenbaum Revista de Neurologia 48 (7), 357-364, 2009 | 10 | 2009 |
TRPM channels come into focus C Bae, A Jara-Oseguera, KJ Swartz Science 359 (6372), 160-161, 2018 | 8 | 2018 |