Novel endogenous peptide agonists of cannabinoid receptors I Gomes, JS Grushko, U Golebiewska, S Hoogendoorn, A Gupta, ... The FASEB Journal 23 (9), 3020, 2009 | 175 | 2009 |
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, ... Nature genetics 50 (3), 460-471, 2018 | 154 | 2018 |
Bioorthogonal chemistry: applications in activity-based protein profiling LI Willems, WA Van der Linden, N Li, KY Li, N Liu, S Hoogendoorn, ... Accounts of chemical research 44 (9), 718-729, 2011 | 122 | 2011 |
Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain MP Baggelaar, FJ Janssen, ACM van Esbroeck, H den Dulk, M Allarà, ... Angew Chem Int Ed Engl 52 (46), 12081-12085, 2013 | 108 | 2013 |
Synthesis of pH-activatable red fluorescent BODIPY dyes with distinct functionalities S Hoogendoorn, AEM Blom, LI Willems, GA Van Der Marel, HS Overkleeft Organic letters 13 (20), 5656-5659, 2011 | 80 | 2011 |
Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite P Van Delft, NJ Meeuwenoord, S Hoogendoorn, J Dinkelaar, ... Organic letters 12 (23), 5486-5489, 2010 | 68 | 2010 |
Synthesis of cyclophellitol, cyclophellitol aziridine, and their tagged derivatives KY Li, J Jiang, MD Witte, WW Kallemeijn, H van den Elst, CS Wong, ... European Journal of Organic Chemistry 2014 (27), 6030-6043, 2014 | 43 | 2014 |
Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study WA van der Linden, N Li, S Hoogendoorn, M Ruben, M Verdoes, J Guo, ... Bioorganic & medicinal chemistry 20 (2), 662-666, 2012 | 37 | 2012 |
Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study N Liu, S Hoogendoorn, B van de Kar, A Kaptein, T Barf, C Driessen, ... Organic & Biomolecular Chemistry 13 (18), 5147-5157, 2015 | 32 | 2015 |
A Multivalent Ligand for the Mannose‐6‐Phosphate Receptor for Endolysosomal Targeting of an Activity‐Based Probe S Hoogendoorn, GHM van Puijvelde, J Kuiper, GA van der Marel, ... Angewandte Chemie 126 (41), 11155-11158, 2014 | 31 | 2014 |
Targeted pH-dependent fluorescent activity-based cathepsin probes S Hoogendoorn, KL Habets, S Passemard, J Kuiper, GA van der Marel, ... Chemical communications 47 (33), 9363-9365, 2011 | 26 | 2011 |
Synthesis and Pharmacological Evaluation of Dimeric Follicle‐Stimulating Hormone Receptor Antagonists KM Bonger, S Hoogendoorn, CJ van Koppen, CM Timmers, HS Overkleeft, ... ChemMedChem 4 (12), 2098-2102, 2009 | 25 | 2009 |
Cytoplasmic dynein antagonists with improved potency and isoform selectivity SK See, S Hoogendoorn, AH Chung, F Ye, JB Steinman, T Sakata-Kato, ... ACS chemical biology 11 (1), 53-60, 2016 | 20 | 2016 |
Development of selective LH receptor agonists by heterodimerization with a FSH receptor antagonist KM Bonger, S Hoogendoorn, CJ van Koppen, CM Timmers, ... ACS Medicinal Chemistry Letters 2 (1), 85-89, 2011 | 19 | 2011 |
From phenotypic hit to chemical probe: chemical biology approaches to elucidate small molecule action in complex biological systems QTL Pasquer, IA Tsakoumagkos, S Hoogendoorn Molecules 25 (23), 5702, 2020 | 15 | 2020 |
Photocleavable fluorescent membrane tension probes: fast release with spatiotemporal control in inner leaflets of plasma membrane, nuclear envelope, and secretory pathway J López‐Andarias, K Eblighatian, QTL Pasquer, L Assies, N Sakai, ... Angewandte Chemie 134 (1), e202113163, 2022 | 14 | 2022 |
Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes WW Kallemeijn, S Scheij, S Hoogendoorn, MD Witte, ... PLoS One 12 (2), e0170268, 2017 | 14 | 2017 |
Targeted delivery of fluorescent high‐mannose‐type oligosaccharide cathepsin inhibitor conjugates CS Wong, S Hoogendoorn, GA van der Marel, HS Overkleeft, JDC Codée ChemPlusChem 80 (6), 928-937, 2015 | 13 | 2015 |
Synthesis and evaluation of hybrid structures composed of two glucosylceramide synthase inhibitors RJ van den Berg, ER van Rijssel, MJ Ferraz, J Houben, A Strijland, ... ChemMedChem 10 (12), 2042-2062, 2015 | 11 | 2015 |
Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib G de Bruin, ED Mock, S Hoogendoorn, AMCH van den Nieuwendijk, ... Chemical communications 52 (21), 4064-4067, 2016 | 10 | 2016 |