| Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1 YH Lee, NY Song, J Suh, DH Kim, W Kim, J Ann, J Lee, JH Baek, HK Na, ... Cancer letters 431, 219-229, 2018 | 67 | 2018 |
| C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition TM Cho, JY Kim, YJ Kim, D Sung, E Oh, S Jang, L Farrand, VH Hoang, ... Cancer letters 447, 141-153, 2019 | 41 | 2019 |
| Discovery of potent human glutaminyl cyclase inhibitors as anti-Alzheimer’s agents based on rational design VH Hoang, PT Tran, M Cui, VTH Ngo, J Ann, J Park, J Lee, K Choi, H Cho, ... Journal of medicinal chemistry 60 (6), 2573-2590, 2017 | 39 | 2017 |
| Structure–activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl) propyl thiourea template PT Tran, VH Hoang, SA Thorat, SE Kim, J Ann, YJ Chang, DW Nam, ... Bioorganic & medicinal chemistry 21 (13), 3821-3830, 2013 | 39 | 2013 |
| Discovery of an orally bioavailable benzofuran analogue that serves as a β-amyloid aggregation inhibitor for the potential treatment of Alzheimer’s disease HJ Ha, DW Kang, HM Kim, JM Kang, J Ann, HJ Hyun, JH Lee, SH Kim, ... Journal of Medicinal Chemistry 61 (1), 396-402, 2018 | 36 | 2018 |
| A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer JM Park, YJ Kim, S Park, M Park, L Farrand, CT Nguyen, J Ann, G Nam, ... Molecular Cancer 19, 1-8, 2020 | 34 | 2020 |
| Development of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer SY Hyun, HT Le, CT Nguyen, YS Yong, HJ Boo, HJ Lee, JS Lee, HY Min, ... Scientific Reports 8 (1), 13924, 2018 | 32 | 2018 |
| Discovery of nonpungent transient receptor potential vanilloid 1 (TRPV1) agonist as strong topical analgesic J Ann, HS Kim, SA Thorat, H Kim, HJ Ha, K Choi, YH Kim, M Kim, ... Journal of medicinal chemistry 63 (1), 418-424, 2019 | 31 | 2019 |
| A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects HJ Lee, HY Min, YS Yong, J Ann, CT Nguyen, MT La, SY Hyun, HT Le, ... Theranostics 12 (1), 105, 2022 | 28 | 2022 |
| Discovery of dual-acting opioid ligand and TRPV1 antagonists as novel therapeutic agents for pain H Lee, S Ahn, J Ann, H Ha, YD Yoo, YH Kim, JY Hwang, KH Hur, CG Jang, ... European journal of medicinal chemistry 182, 111634, 2019 | 28 | 2019 |
| TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides TH Ha, HC Ryu, SE Kim, HS Kim, J Ann, PT Tran, VH Hoang, K Son, ... Bioorganic & medicinal chemistry 21 (21), 6657-6664, 2013 | 28 | 2013 |
| Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors HS Kim, M Hong, J Ann, S Yoon, CT Nguyen, SC Lee, HY Lee, YG Suh, ... Bioorganic & Medicinal Chemistry 24 (22), 6082-6093, 2016 | 27 | 2016 |
| Discovery of an orally bioavailable gonadotropin-releasing hormone receptor antagonist SM Kim, M Lee, SY Lee, E Park, SM Lee, EJ Kim, MY Han, T Yoo, J Ann, ... Journal of Medicinal Chemistry 59 (19), 9150-9172, 2016 | 27 | 2016 |
| Differential regulation of gene expression in lung cancer cells by diacyglycerol-lactones and a phorbol ester via selective activation of protein kinase C isozymes M Cooke, V Casado-Medrano, J Ann, J Lee, PM Blumberg, MC Abba, ... Scientific reports 9 (1), 6041, 2019 | 25 | 2019 |
| 2-(3-Fluoro-4-methylsulfonylaminophenyl) propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region SA Thorat, DW Kang, HC Ryu, MS Kim, HS Kim, J Ann, T Ha, SE Kim, ... European journal of medicinal chemistry 64, 589-602, 2013 | 25 | 2013 |
| Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes M Cooke, X Zhou, V Casado-Medrano, C Lopez-Haber, MJ Baker, R Garg, ... Journal of Biological Chemistry 293 (22), 8330-8341, 2018 | 23 | 2018 |
| Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region VTH Ngo, VH Hoang, PT Tran, J Ann, M Cui, G Park, S Choi, J Lee, H Kim, ... Bioorganic & medicinal chemistry 26 (5), 1035-1049, 2018 | 23 | 2018 |
| Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors VTH Ngo, VH Hoang, PT Tran, N Van Manh, J Ann, E Kim, M Cui, S Choi, ... Bioorganic & Medicinal Chemistry 26 (12), 3133-3144, 2018 | 20 | 2018 |
| Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides as potent TRPV1 antagonists S Lee, C Kim, J Ann, SA Thorat, E Kim, J Park, S Choi, PM Blumberg, ... Bioorganic & medicinal chemistry letters 27 (18), 4383-4388, 2017 | 20 | 2017 |
| Investigation of B, C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents HS Kim, VH Hoang, M Hong, KC Kim, J Ann, CT Nguyen, JH Seo, H Choi, ... Bioorganic & Medicinal Chemistry 27 (7), 1370-1381, 2019 | 19 | 2019 |
Jeewoo LeeSeoul National UniversityBestätigte E-Mail-Adresse bei snu.ac.kr
