| Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 159 | 2015 |
| Characterization of rare, dormant, and therapy-resistant cells in acute lymphoblastic leukemia S Ebinger, EZ Özdemir, C Ziegenhain, S Tiedt, CC Alves, M Grunert, ... Cancer cell 30 (6), 849-862, 2016 | 137 | 2016 |
| Method of conditional moments (MCM) for the chemical master equation J Hasenauer, V Wolf, A Kazeroonian, FJ Theis Journal of mathematical biology 69 (3), 687-735, 2014 | 111 | 2014 |
| Network plasticity of pluripotency transcription factors in embryonic stem cells A Filipczyk, C Marr, S Hastreiter, J Feigelman, M Schwarzfischer, ... Nature cell biology 17 (10), 1235-1246, 2015 | 108 | 2015 |
| Identification of models of heterogeneous cell populations from population snapshot data J Hasenauer, S Waldherr, M Doszczak, N Radde, P Scheurich, F Allgöwer BMC bioinformatics 12 (1), 1-15, 2011 | 102 | 2011 |
| Determinants of robustness in spindle assembly checkpoint signalling S Heinrich, EM Geissen, J Kamenz, S Trautmann, C Widmer, P Drewe, ... Nature cell biology 15 (11), 1328-1339, 2013 | 101 | 2013 |
| Scalable parameter estimation for genome-scale biochemical reaction networks F Fröhlich, B Kaltenbacher, FJ Theis, J Hasenauer PLoS computational biology 13 (1), e1005331, 2017 | 98 | 2017 |
| High-dimensional Bayesian parameter estimation: Case study for a model of JAK2/STAT5 signaling S Hug, A Raue, J Hasenauer, J Bachmann, U Klingmüller, J Timmer, ... Mathematical biosciences 246 (2), 293-304, 2013 | 61 | 2013 |
| PESTO: parameter estimation toolbox P Stapor, D Weindl, B Ballnus, S Hug, C Loos, A Fiedler, S Krause, ... Bioinformatics 34 (4), 705-707, 2018 | 58 | 2018 |
| Inference for stochastic chemical kinetics using moment equations and system size expansion F Fröhlich, P Thomas, A Kazeroonian, FJ Theis, R Grima, J Hasenauer PLoS computational biology 12 (7), e1005030, 2016 | 56 | 2016 |
| COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms M Ostaszewski, A Mazein, ME Gillespie, I Kuperstein, A Niarakis, ... Scientific data 7 (1), 1-4, 2020 | 53 | 2020 |
| Benchmarking optimization methods for parameter estimation in large kinetic models AF Villaverde, F Fröhlich, D Weindl, J Hasenauer, JR Banga Bioinformatics 35 (5), 830-838, 2019 | 49 | 2019 |
| Efficient parameter estimation enables the prediction of drug response using a mechanistic pan-cancer pathway model F Fröhlich, T Kessler, D Weindl, A Shadrin, L Schmiester, H Hache, ... Cell systems 7 (6), 567-579. e6, 2018 | 49 | 2018 |
| Parameter identification, experimental design and model falsification for biological network models using semidefinite programming J Hasenauer, S Waldherr, K Wagner, F Allgöwer IET systems biology 4 (2), 119-130, 2010 | 46 | 2010 |
| ODE constrained mixture modelling: a method for unraveling subpopulation structures and dynamics J Hasenauer, C Hasenauer, T Hucho, FJ Theis PLoS Comput Biol 10 (7), e1003686, 2014 | 45 | 2014 |
| Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes S Neumann, J Hasenauer, N Pollak, P Scheurich Journal of Biological Chemistry 289 (23), 16576-16587, 2014 | 43 | 2014 |
| GenSSI 2.0: multi-experiment structural identifiability analysis of SBML models TS Ligon, F Fröhlich, OT Chiş, JR Banga, E Balsa-Canto, J Hasenauer Bioinformatics 34 (8), 1421-1423, 2018 | 41 | 2018 |
| Parallelization and high-performance computing enables automated statistical inference of multi-scale models N Jagiella, D Rickert, FJ Theis, J Hasenauer Cell Systems 4 (2), 194-206. e9, 2017 | 41 | 2017 |
| CERENA: ChEmical REaction Network Analyzer—a toolbox for the simulation and analysis of stochastic chemical kinetics A Kazeroonian, F Fröhlich, A Raue, FJ Theis, J Hasenauer PloS one 11 (1), e0146732, 2016 | 39 | 2016 |
| Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia C Andres, J Hasenauer, HS Ahn, EK Joseph, J Isensee, FJ Theis, ... PAIN® 154 (10), 2216-2226, 2013 | 39 | 2013 |
