Chromatin architecture emerges during zygotic genome activation independent of transcription CB Hug, AG Grimaldi, K Kruse, JM Vaquerizas Cell 169 (2), 216-228. e19, 2017 | 467 | 2017 |
Machine learning identifies candidates for drug repurposing in Alzheimer’s disease S Rodriguez, C Hug, P Todorov, N Moret, SA Boswell, K Evans, G Zhou, ... Nature communications 12 (1), 1033, 2021 | 199 | 2021 |
FAN-C: a feature-rich framework for the analysis and visualisation of chromosome conformation capture data K Kruse, CB Hug, JM Vaquerizas Genome biology 21, 1-19, 2020 | 154 | 2020 |
The birth of the 3D genome during early embryonic development CB Hug, JM Vaquerizas Trends in Genetics 34 (12), 903-914, 2018 | 81 | 2018 |
TADtool: visual parameter identification for TAD-calling algorithms K Kruse, CB Hug, B Hernández-Rodríguez, JM Vaquerizas Bioinformatics 32 (20), 3190-3192, 2016 | 78 | 2016 |
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia MR Mansour, S He, Z Li, R Lobbardi, BJ Abraham, C Hug, S Rahman, ... Journal of Experimental Medicine 215 (7), 1929-1945, 2018 | 31 | 2018 |
A resource for exploring the understudied human kinome for research and therapeutic opportunities N Moret, C Liu, BM Gyori, JA Bachman, A Steppi, C Hug, R Taujale, ... BioRxiv, 2020.04. 02.022277, 2020 | 29 | 2020 |
Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity M Mallik, M Catinozzi, CB Hug, L Zhang, M Wagner, J Bussmann, J Bittern, ... Journal of Cell Biology 217 (11), 3947-3964, 2018 | 25 | 2018 |
Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ... Cell reports 42 (3), 2023 | 14 | 2023 |
FAN-C: A Feature-rich Framework for the Analysis and Visualisation of C data K Kruse, CB Hug, JM Vaquerizas BioRxiv, 2020.02. 03.932517, 2020 | 9 | 2020 |
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation M Rogava, TJ Aprati, WY Chi, JC Melms, C Hug, SH Davis, EM Earlie, ... Nature cancer 5 (3), 433-447, 2024 | 7 | 2024 |
A community-based approach to image analysis of cells, tissues and tumors JC Vizcarra, EA Burlingame, CB Hug, Y Goltsev, BS White, DR Tyson, ... Computerized Medical Imaging and Graphics 95, 102013, 2022 | 6 | 2022 |
Generation of genome-wide chromatin conformation capture libraries from tightly staged early Drosophila embryos CB Hug, JM Vaquerizas Journal of Visualized Experiments: Jove, 2018 | 3 | 2018 |
Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma T Kader, JR Lin, C Hug, S Coy, YA Chen, I de Bruijn, N Shih, E Jung, ... bioRxiv, 2024 | 1 | 2024 |
TYK2 as a novel therapeutic target in Alzheimer’s Disease with TDP-43 inclusions LE König, S Rodriguez, C Hug, S Daneshvari, A Chung, GA Bradshaw, ... bioRxiv, 2024 | 1 | 2024 |
Sendai virus persistence questions the transient naive reprogramming method for iPSC generation A De Los Angeles, CB Hug, VN Gladyshev, GM Church, S Velychko bioRxiv, 2024 | 1 | 2024 |
Multi range ERK responses shape the proliferative trajectory of single cells following oncogene induced senescence JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ... bioRxiv, 2022.10. 06.511142, 2022 | 1 | 2022 |
Machine learning identifies novel candidates for drug repurposing in Alzheimer’s Disease S Rodriguez, C Hug, P Todorov, N Moret, SA Boswell, K Evans, G Zhou, ... bioRxiv, 2020.05. 15.098749, 2020 | 1 | 2020 |
Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development T Kader, JR Lin, S Coy, C Hug, YA Chen, RJ Pelletier, M Leon, J Lee, ... Cancer Research 84 (7_Supplement), LB311-LB311, 2024 | | 2024 |
TYK2 as a novel therapeutic target in Alzheimer Disease L Konig, S Rodriguez, C Hug, S Daneshvari, A Chung, G Bradshaw, ... bioRxiv, 2024.06. 04.595773, 2024 | | 2024 |