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Marten Hornsveld
Marten Hornsveld
Senior Scientist, Crown Bioscience NL
Bestätigte E-Mail-Adresse bei crownbio.com
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Zitiert von
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Jahr
Interplay between metabolic identities in the intestinal crypt supports stem cell function
MJ Rodríguez-Colman, M Schewe, M Meerlo, E Stigter, J Gerrits, ...
Nature 543 (7645), 424-427, 2017
4552017
TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer
W Hua, P Ten Dijke, S Kostidis, M Giera, M Hornsveld
Cellular and Molecular Life Sciences 77, 2103-2123, 2020
1802020
Re-evaluating the role of FOXOs in cancer
M Hornsveld, TB Dansen, PW Derksen, BMT Burgering
Seminars in cancer biology 50, 90-100, 2018
1602018
Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice
PWB Derksen, TM Braumuller, E van der Burg, M Hornsveld, E Mesman, ...
Disease models & mechanisms 4 (3), 347-358, 2011
1492011
The hallmarks of cancer from a redox perspective
M Hornsveld, TB Dansen
Antioxidants & redox signaling 25 (6), 300-325, 2016
1102016
Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells
S Moutinho-Pereira, N Stuurman, O Afonso, M Hornsveld, P Aguiar, ...
Proceedings of the National Academy of Sciences 110 (49), 19808-19813, 2013
792013
FOXO transcription factors both suppress and support breast cancer progression
M Hornsveld, LMM Smits, M Meerlo, M Van Amersfoort, ...
Cancer research 78 (9), 2356-2369, 2018
732018
Assessment of functional phosphatidylinositol 3-kinase pathway activity in cancer tissue using forkhead box-O target gene expression in a knowledge-based computational model
H Van Ooijen, M Hornsveld, C Dam-de Veen, R Velter, M Dou, ...
The American journal of pathology 188 (9), 1956-1972, 2018
562018
FOXO s support the metabolic requirements of normal and tumor cells by promoting IDH 1 expression
P Charitou, M Rodriguez‐Colman, J Gerrits, M van Triest, ...
EMBO reports 16 (4), 456-466, 2015
492015
Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer
M Hornsveld, M Tenhagen, RA Van de Ven, AMM Smits, MH Van Triest, ...
Cell Death & Differentiation 23 (9), 1483-1492, 2016
472016
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
M Hornsveld, FM Feringa, L Krenning, J van den Berg, LMM Smits, ...
Cell Reports 34 (4), 2021
122021
Nonhuman primate adenoviruses of the human adenovirus B species are potent and broadly acting oncolytic vector candidates
STF Bots, V Kemp, SJ Cramer, DJM van den Wollenberg, M Hornsveld, ...
Human Gene Therapy 33 (5-6), 275-289, 2022
102022
Dynamic visualization of TGF-β/SMAD3 transcriptional responses in single living cells
DL Marvin, L You, L Bornes, M van Dinther, N Peters, H Dang, SK Hakuno, ...
Cancers 14 (10), 2508, 2022
92022
Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition
W Hua, S Kostidis, O Mayboroda, M Giera, M Hornsveld, P Ten Dijke
Metabolites 11 (9), 626, 2021
92021
A novel pancreatic cancer mini-tumor model to study desmoplasia and myofibroblastic cancer-associated fibroblast differentiation
TJ Harryvan, L Hawinkels, A Inderson, JE van Hooft, P Micke, ...
Gastro Hep Advances 1 (4), 678-681, 2022
82022
Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus
TJ Harryvan, M Golo, N Dam, MJA Schoonderwoerd, EA Farshadi, ...
Cancer Gene Therapy 29 (12), 1918-1929, 2022
62022
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells
LM Sluimer, E Bullock, MAK Rätze, L Enserink, C Overbeeke, ...
Journal of Cell Science 136 (3), jcs260243, 2023
42023
Abstract LB435: Large panel organoid drug testing combined with biomarker analysis: Unveiling prospects for mechanism of action identification and preclinical patient …
L Xue, L Wijler, M Hornsveld, S Guo, L Price, M Putker, L Bourre
Cancer Research 84 (7_Supplement), LB435-LB435, 2024
2024
Mini-tumors: Pre-clinical HCI assays to screen anti-cancer drugs in the context of organoids, cancer-associated fibroblasts and immune cells
M Hornsveld, G Odenkirchen, C van Dort, JG Mateos, S de Man, ...
Cancer Research 83 (7_Supplement), 579-579, 2023
2023
High content screening of ovarian organoid models to accelerate anti-cancer drug discovery
M Hornsveld, M Madej, JG Mateos, G Goverse, M Putker, E Spanjaard, ...
European Journal of Cancer 174, S114, 2022
2022
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