|The landscape of genomic alterations across childhood cancers|
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
|Molecular recording of mammalian embryogenesis|
MM Chan, ZD Smith, S Grosswendt, H Kretzmer, TM Norman, B Adamson, ...
Nature 570 (7759), 77-82, 2019
|Metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data|
F Jühling, H Kretzmer, SH Bernhart, C Otto, PF Stadler, S Hoffmann
Genome research 26 (2), 256-262, 2016
|DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control|
H Kretzmer, SH Bernhart, W Wang, A Haake, MA Weniger, AK Bergmann, ...
Nature genetics 47 (11), 1316-1325, 2015
|MINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells|
G Doose, A Haake, SH Bernhart, C López, S Duggimpudi, F Wojciech, ...
Proceedings of the National Academy of Sciences 112 (38), E5261-E5270, 2015
|Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer|
SH Bernhart, H Kretzmer, LM Holdt, F Jühling, O Ammerpohl, ...
Scientific reports 6 (1), 1-18, 2016
|Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites|
JV Veenvliet, A Bolondi, H Kretzmer, L Haut, M Scholze-Wittler, D Schifferl, ...
Science 370 (6522), 2020
|Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing|
P Giesselmann, B Brändl, E Raimondeau, R Bowen, C Rohrandt, ...
Nature biotechnology 37 (12), 1478-1481, 2019
|Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma|
C López, K Kleinheinz, SM Aukema, M Rohde, SH Bernhart, ...
Nature communications 10 (1), 1-19, 2019
|Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis|
K Hezaveh, A Kloetgen, SH Bernhart, KD Mahapatra, D Lenze, J Richter, ...
Haematologica 101 (11), 1380, 2016
|Epigenetic regulator function through mouse gastrulation|
S Grosswendt, H Kretzmer, ZD Smith, AS Kumar, S Hetzel, L Wittler, ...
Nature 584 (7819), 102-108, 2020
|BAT: Bisulfite Analysis Toolkit: BAT is a toolkit to analyze DNA methylation sequencing data accurately and reproducibly. It covers standard processing and analysis steps from …|
H Kretzmer, C Otto, S Hoffmann
F1000Research 6, 2017
|Nanopype: a modular and scalable nanopore data processing pipeline|
P Giesselmann, S Hetzel, FJ Müller, A Meissner, H Kretzmer
Bioinformatics 35 (22), 4770-4772, 2019
|Preneoplastic alterations define CLL DNA methylome and persist through disease progression and therapy|
H Kretzmer, A Biran, N Purroy, C Lemvigh, K Clement, M Gruber, H Gu, ...
Blood cancer discovery 2 (1), 54, 2021
|Dissecting the DNA binding landscape and gene regulatory network of p63 and p53|
K Riege, H Kretzmer, A Sahm, SS McDade, S Hoffmann, M Fischer
Elife 9, e63266, 2020
|Dnmt1 has de novo activity targeted to transposable elements|
C Haggerty, H Kretzmer, C Riemenschneider, AS Kumar, AL Mattei, ...
Nature Structural & Molecular Biology, 1-10, 2021
|The CLL-1100 project: towards complete genomic characterization and improved prognostics for CLL|
BA Knisbacher, Z Lin, CK Hahn, F Nadeu, M Duran-Ferrer, KE Stevenson, ...
Blood 136, 3-4, 2020
|Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas|
D Hübschmann, K Kleinheinz, R Wagener, SH Bernhart, C López, ...
Leukemia, 1-15, 2021
|Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo|
A Biran, H Kretzmer, S Yin, L Billington, FF Regis, AW Mohammad, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
|RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data|
S Hetzel, P Giesselmann, K Reinert, A Meissner, H Kretzmer