Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells A Rezania, JE Bruin, P Arora, A Rubin, I Batushansky, A Asadi, S O'dwyer, ... Nature biotechnology 32 (11), 1121, 2014 | 1681 | 2014 |
Mechanisms of pancreatic β-cell apoptosis in diabetes and its therapies JD Johnson, YHC Yang, DS Luciani Islets of Langerhans, 2. ed., 1-20, 2013 | 101 | 2013 |
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes M Szabat, TB Kalynyak, GE Lim, KY Chu, YH Yang, A Asadi, BK Gage, ... Cell death & disease 2 (11), e232, 2011 | 63 | 2011 |
Intraislet SLIT–ROBO signaling is required for beta-cell survival and potentiates insulin secretion YHC Yang, JEM Fox, KL Zhang, PE MacDonald, JD Johnson Proceedings of the National Academy of Sciences 110 (41), 16480-16485, 2013 | 62 | 2013 |
Effects of insulin on human pancreatic cancer progression modeled in vitro MT Chan, GE Lim, S Skovsų, YHC Yang, T Albrecht, EU Alejandro, ... BMC cancer 14 (1), 814, 2014 | 44 | 2014 |
Multiparameter Screening Reveals a Role for Na+ Channels in Cytokine-Induced β-Cell Death YHC Yang, YY Vilin, M Roberge, HT Kurata, JD Johnson Molecular endocrinology 28 (3), 406-417, 2014 | 38 | 2014 |
Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic β-cells YHC Yang, JD Johnson J Cell Sci 126 (18), 4286-4295, 2013 | 37 | 2013 |
High-content screening identifies a role for Na+ channels in insulin production M Szabat, H Modi, R Ramracheya, V Girbinger, F Chan, JTC Lee, M Piske, ... Royal Society open science 2 (12), 150306, 2015 | 35 | 2015 |
A new mode of pancreatic islet innervation revealed by live imaging in zebrafish YHC Yang, K Kawakami, DYR Stainier Elife 7, e34519, 2018 | 26 | 2018 |
A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression JA Hill, M Szabat, CA Hoesli, BK Gage, YHC Yang, DE Williams, ... PLoS One 5 (9), e12958, 2010 | 23 | 2010 |
Innervation modulates the functional connectivity between pancreatic endocrine cells YHC Yang, LJB Briant, CA Raab, ST Mullapudi, HM Maischein, ... Elife 11, e64526, 2022 | 20 | 2022 |
Bax and Bak jointly control survival and dampen the early unfolded protein response in pancreatic β-cells under glucolipotoxic stress SA White, LS Zhang, DJ Pasula, YHC Yang, DS Luciani Scientific Reports 10 (1), 1-12, 2020 | 19 | 2020 |
Whole-Organism Chemical Screening Identifies Modulators of Pancreatic β-Cell Function H Matsuda, ST Mullapudi, YHC Yang, H Masaki, D Hesselson, ... Diabetes 67 (11), 2268-2279, 2018 | 17 | 2018 |
Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function ST Mullapudi, GLM Boezio, A Rossi, M Marass, RL Matsuoka, H Matsuda, ... Development 146 (21), 2019 | 16 | 2019 |
Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists ST Mullapudi, CSM Helker, GLM Boezio, HM Maischein, AM Sokol, ... Elife 7, e42209, 2018 | 15 | 2018 |
A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells YHC Yang, QF Wills, JD Johnson Diabetologia 58 (6), 1239-1249, 2015 | 15 | 2015 |
Brain-body control of glucose homeostasis: insights from model organisms AJ MacDonald, YHC Yang, A Miguel Cruz, C Beall, KLJ Ellacott Frontiers in Endocrinology 12, 303, 2021 | 11 | 2021 |
Innervation modulates the functional connectivity between pancreatic endocrine cells YHC Yang, LJB Briant, C Raab, ST Mullapudi, HM Maischein, ... bioRxiv, 2020 | | 2020 |
Neural crest cells are required for autonomic innervation of the endocrine pancreas YHC Yang, DYR Stainier DIABETOLOGIA 59, S201-S201, 2016 | | 2016 |
Whole organism chemical screening to identify modulators of beta cell function H Matsuda, ST Mullapudi, YHC Yang, D Hesselson, DYR Stainier DIABETOLOGIA 59, S260-S260, 2016 | | 2016 |