| 1.8 and 1.9 Å resolution structures of the Penicillium amagasakiense and Aspergillus niger glucose oxidases as a basis for modelling substrate complexes G Wohlfahrt, S Witt, J Hendle, D Schomburg, HM Kalisz, HJ Hecht Acta Crystallographica Section D: Biological Crystallography 55 (5), 969-977, 1999 | 448 | 1999 |
| Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies AM Moilanen, R Riikonen, R Oksala, L Ravanti, E Aho, G Wohlfahrt, ... Scientific reports 5 (1), 12007, 2015 | 385 | 2015 |
| Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors V Leskovac, S Trivić, G Wohlfahrt, J Kandrač, D Peričin The international journal of biochemistry & cell biology 37 (4), 731-750, 2005 | 329 | 2005 |
| Trichoderma reesei cellobiohydrolases: why so efficient on crystalline cellulose? TT Teeri, A Koivula, M Linder, G Wohlfahrt, C Divne, TA Jones Biochemical Society Transactions 26 (2), 173-177, 1998 | 258 | 1998 |
| The Active Site of Cellobiohydrolase Cel6A from Trichoderma reesei: The Roles of Aspartic Acids D221 and D175 A Koivula, L Ruohonen, G Wohlfahrt, T Reinikainen, TT Teeri, K Piens, ... Journal of the American Chemical Society 124 (34), 10015-10024, 2002 | 179 | 2002 |
| The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket M Suchanek, R Hynynen, G Wohlfahrt, M Lehto, M Johansson, ... Biochemical Journal 405 (3), 473-480, 2007 | 170 | 2007 |
| Conserved arginine-516 of Penicillium amagasakiense glucose oxidase is essential for the efficient binding of β-D-glucose S WITT, G WOHLFAHRT, D SCHOMBURG, HJ HECHT, HM KALISZ Biochemical Journal 347 (2), 553-559, 2000 | 155 | 2000 |
| Polypharmacology modelling using proteochemometrics (PCM): recent methodological developments, applications to target families, and future prospects I Cortés-Ciriano, QU Ain, V Subramanian, EB Lenselink, O Méndez-Lucio, ... MedChemComm 6 (1), 24-50, 2015 | 120 | 2015 |
| The chemical mechanism of action of glucose oxidase from Aspergillus niger G Wohlfahrt, S Trivić, J Zeremski, D Peričin, V Leskovac Molecular and cellular biochemistry 260, 69-83, 2004 | 120 | 2004 |
| Sterol binding by OSBP-related protein 1L regulates late endosome motility and function T Vihervaara, RL Uronen, G Wohlfahrt, I Björkhem, E Ikonen, ... Cellular and molecular life sciences 68, 537-551, 2011 | 111 | 2011 |
| Analysis of the catalyic mechanism of a fungal lipase using computer-aided design and structural mutants HD Beer, G Wohlfahrt, JEG McCarthy, D Schomburg, RD Schmid Protein Engineering, Design and Selection 9 (6), 507-517, 1996 | 94 | 1996 |
| Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/A224H/L225V/T226A/D262G mutant D Becker, C Braet, H BRUMER III, M Claeyssens, C Divne, ... Biochemical Journal 356 (1), 19-30, 2001 | 90 | 2001 |
| The folding and activity of the extracellular lipase of Rhizopus oryzae are modulated by a prosequence HD Beer, G Wohlfahrt, RD SCHMID, JEG McCARTHY Biochemical journal 319 (2), 351-359, 1996 | 89 | 1996 |
| Structure and phospholipid transfer activity of human PLTP: analysis by molecular modeling and site-directed mutagenesis J Huuskonen, G Wohlfahrt, M Jauhiainen, C Ehnholm, O Teleman, ... Journal of lipid research 40 (6), 1123-1130, 1999 | 81 | 1999 |
| Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanism R Gilboa, A Spungin‐Bialik, G Wohlfahrt, D Schomburg, S Blumberg, ... Proteins: Structure, Function, and Bioinformatics 44 (4), 490-504, 2001 | 72 | 2001 |
| Aspects of the mechanism of catalysis of glucose oxidase: A docking, molecular mechanics and quantum chemical study M Meyer, G Wohlfahrt, J Knäblein, D Schomburg Journal of computer-aided molecular design 12, 425-440, 1998 | 71 | 1998 |
| Interactions of Streptomyces griseus aminopeptidase with a methionine product analogue: a structural study at 1.53 Å resolution R Gilboa, HM Greenblatt, M Perach, A Spungin-Bialik, U Lessel, ... Acta Crystallographica Section D: Biological Crystallography 56 (5), 551-558, 2000 | 60 | 2000 |
| Novel small molecule inhibitors for prostate‐specific antigen H Koistinen, G Wohlfahrt, JM Mattsson, P Wu, J Lahdenperä, UH Stenman The Prostate 68 (11), 1143-1151, 2008 | 57 | 2008 |
| Probing pH-Dependent Functional Elements in Proteins: Modification of Carboxylic Acid Pairs in Trichoderma reesei Cellobiohydrolase Cel6A G Wohlfahrt, T Pellikka, H Boer, TT Teeri, A Koivula Biochemistry 42 (34), 10095-10103, 2003 | 55 | 2003 |
| Requirements for transcriptional regulation by the orphan nuclear receptor ERRgamma J Huppunen, G Wohlfahrt, P Aarnisalo Molecular and cellular endocrinology 219 (1-2), 151-160, 2004 | 53 | 2004 |
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