International union of basic and clinical pharmacology. XCVIII. Histamine receptors P Panula, PL Chazot, M Cowart, R Gutzmer, R Leurs, WLS Liu, H Stark, ... Pharmacological reviews 67 (3), 601-655, 2015 | 626 | 2015 |
High constitutive activity of native H3 receptors regulates histamine neurons in brain S Morisset, A Rouleau, X Ligneau, F Gbahou, J Tardivel-Lacombe, ... Nature 408 (6814), 860-864, 2000 | 592 | 2000 |
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function E Bézard, S Ferry, U Mach, H Stark, L Leriche, T Boraud, C Gross, ... Nature medicine 9 (6), 762-767, 2003 | 455 | 2003 |
Polypharmacology by design: a medicinal chemist’s perspective on multitargeting compounds E Proschak, H Stark, D Merk Journal of medicinal chemistry 62 (2), 420-444, 2018 | 419 | 2018 |
Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist X Ligneau, JS Lin, G Vanni-Mercier, M Jouvet, JL Muir, CR Ganellin, ... Journal of Pharmacology and Experimental Therapeutics 287 (2), 658-666, 1998 | 319 | 1998 |
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells R Gutzmer, C Diestel, S Mommert, B Köther, H Stark, M Wittmann, ... The Journal of Immunology 174 (9), 5224-5232, 2005 | 288 | 2005 |
Identification of dopamine D1–D3 receptor heteromers: indications for a role of synergistic D1–D3 receptor interactions in the striatum D Marcellino, S Ferré, V Casadó, A Cortés, B Le Foll, C Mazzola, F Drago, ... Journal of Biological Chemistry 283 (38), 26016-26025, 2008 | 287 | 2008 |
The histamine H4 receptor is functionally expressed on TH2 cells R Gutzmer, S Mommert, M Gschwandtner, K Zwingmann, H Stark, ... Journal of Allergy and Clinical Immunology 123 (3), 619-625, 2009 | 257 | 2009 |
DOGS: Reaction-Driven de novo Design of Bioactive Compounds M Hartenfeller, H Zettl, M Walter, M Rupp, F Reisen, E Proschak, ... PLoS computational biology 8 (2), e1002380, 2012 | 255 | 2012 |
BF2. 649 [1-{3-[3-(4-Chlorophenyl) propoxy] propyl} piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical … X Ligneau, D Perrin, L Landais, JC Camelin, TPG Calmels, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 365-375, 2007 | 251 | 2007 |
Histamine H3 receptor antagonists go to clinics K Sander, T Kottke, H Stark Biological and Pharmaceutical Bulletin 31 (12), 2163-2181, 2008 | 231 | 2008 |
Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats A Lecklin, P Etu-Seppälä, H Stark, L Tuomisto Brain research 793 (1-2), 279-288, 1998 | 204 | 1998 |
Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases B Sadek, A Saad, A Sadeq, F Jalal, H Stark Behavioural brain research 312, 415-430, 2016 | 188 | 2016 |
Histamine H3 and H4 receptors as novel drug targets E Tiligada, E Zampeli, K Sander, H Stark Expert opinion on investigational drugs 18 (10), 1519-1531, 2009 | 187 | 2009 |
Protean agonism at histamine H3 receptors in vitro and in vivo F Gbahou, A Rouleau, S Morisset, R Parmentier, S Crochet, JS Lin, ... Proceedings of the National Academy of Sciences 100 (19), 11086-11091, 2003 | 182 | 2003 |
Distinct pharmacology of rat and human histamine H3 receptors: role of two amino acids in the third transmembrane domain X Ligneau, S Morisset, J Tardivel‐Lacombe, F Gbahou, CR Ganellin, ... British journal of pharmacology 131 (7), 1247-1250, 2000 | 175 | 2000 |
[125I] iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors. X Ligneau, M Garbarg, ML Vizuete, J Diaz, K Purand, H Stark, ... Journal of Pharmacology and Experimental Therapeutics 271 (1), 452-459, 1994 | 175 | 1994 |
Histamine H1, H3 and H4 receptors are involved in pruritus K Rossbach, C Nassenstein, M Gschwandtner, D Schnell, K Sander, ... Neuroscience 190, 89-102, 2011 | 162 | 2011 |
Histamine H4 receptor antagonism reduces hapten‐induced scratching behaviour but not inflammation K Roßbach, S Wendorff, K Sander, H Stark, R Gutzmer, T Werfel, ... Experimental dermatology 18 (1), 57-63, 2009 | 162 | 2009 |
Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors C Guigoni, I Aubert, Q Li, VV Gurevich, JL Benovic, S Ferry, U Mach, ... Parkinsonism & related disorders 11, S25-S29, 2005 | 162 | 2005 |