Peter Espenshade
Peter Espenshade
Professor of Cell Biology, Johns Hopkins University SOM
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Zitiert von
Zitiert von
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
T Yang, PJ Espenshade, ME Wright, D Yabe, Y Gong, R Aebersold, ...
Cell 110 (4), 489-500, 2002
Regulation of sterol synthesis in eukaryotes
PJ Espenshade, AL Hughes
Annu. Rev. Genet. 41, 401-427, 2007
Expanding roles for SREBP in metabolism
W Shao, PJ Espenshade
Cell metabolism 16 (4), 414-419, 2012
Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
J Sakai, RB Rawson, PJ Espenshade, D Cheng, AC Seegmiller, ...
Molecular cell 2 (4), 505-514, 1998
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
A Nohturfft, D Yabe, JL Goldstein, MS Brown, PJ Espenshade
Cell 102 (3), 315-323, 2000
Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
RA DeBose-Boyd, MS Brown, WP Li, A Nohturfft, JL Goldstein, ...
Cell 99 (7), 703-712, 1999
SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast
AL Hughes, BL Todd, PJ Espenshade
Cell 120 (6), 831-842, 2005
Regulation of HMG-CoA reductase in mammals and yeast
JS Burg, PJ Espenshade
Progress in lipid research 50 (4), 403-410, 2011
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
TF Osborne, PJ Espenshade
Genes & development 23 (22), 2578-2591, 2009
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes
AL Hughes, DW Powell, M Bard, J Eckstein, R Barbuch, AJ Link, ...
Cell metabolism 5 (2), 143-149, 2007
SREBPs: sterol-regulated transcription factors
PJ Espenshade
Journal of cell science 119 (6), 973-976, 2006
Hierarchical modularity and the evolution of genetic interactomes across species
CJ Ryan, A Roguev, K Patrick, J Xu, H Jahari, Z Tong, P Beltrao, M Shales, ...
Molecular cell 46 (5), 691-704, 2012
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
YC Chang, CM Bien, H Lee, PJ Espenshade, KJ Kwon‐Chung
Molecular microbiology 64 (3), 614-629, 2007
Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.
P Espenshade, RE Gimeno, E Holzmacher, P Teung, CA Kaiser
The Journal of cell biology 131 (2), 311-324, 1995
Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins
PJ Espenshade, D Cheng, JL Goldstein, MS Brown
Journal of Biological Chemistry 274 (32), 22795-22804, 1999
LST1 Is a SEC24 Homologue Used for Selective Export of the Plasma Membrane ATPase from the Endoplasmic Reticulum
KJ Roberg, M Crotwell, P Espenshade, R Gimeno, CA Kaiser
The Journal of cell biology 145 (4), 659-672, 1999
Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast
BL Todd, EV Stewart, JS Burg, AL Hughes, PJ Espenshade
Molecular and cellular biology 26 (7), 2817-2831, 2006
Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER
PJ Espenshade, WP Li, D Yabe
Proceedings of the National Academy of Sciences 99 (18), 11694-11699, 2002
COPII subunit interactions in the assembly of the vesicle coat
DA Shaywitz, PJ Espenshade, RE Gimeno, CA Kaiser
Journal of Biological Chemistry 272 (41), 25413-25416, 1997
Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis
CM Bien, PJ Espenshade
Eukaryotic cell 9 (3), 352-359, 2010
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