| Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER T Yang, PJ Espenshade, ME Wright, D Yabe, Y Gong, R Aebersold, ... Cell 110 (4), 489-500, 2002 | 1236 | 2002 |
| Regulation of sterol synthesis in eukaryotes PJ Espenshade, AL Hughes Annu. Rev. Genet. 41 (1), 401-427, 2007 | 648 | 2007 |
| Expanding roles for SREBP in metabolism W Shao, PJ Espenshade Cell metabolism 16 (4), 414-419, 2012 | 553 | 2012 |
| Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells J Sakai, RB Rawson, PJ Espenshade, D Cheng, AC Seegmiller, ... Molecular cell 2 (4), 505-514, 1998 | 529 | 1998 |
| Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes A Nohturfft, D Yabe, JL Goldstein, MS Brown, PJ Espenshade Cell 102 (3), 315-323, 2000 | 420 | 2000 |
| Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi RA DeBose-Boyd, MS Brown, WP Li, A Nohturfft, JL Goldstein, ... Cell 99 (7), 703-712, 1999 | 387 | 1999 |
| SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast AL Hughes, BL Todd, PJ Espenshade Cell 120 (6), 831-842, 2005 | 370 | 2005 |
| Regulation of HMG-CoA reductase in mammals and yeast JS Burg, PJ Espenshade Progress in lipid research 50 (4), 403-410, 2011 | 327 | 2011 |
| Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes AL Hughes, DW Powell, M Bard, J Eckstein, R Barbuch, AJ Link, ... Cell metabolism 5 (2), 143-149, 2007 | 282 | 2007 |
| Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been TF Osborne, PJ Espenshade Genes & development 23 (22), 2578-2591, 2009 | 281 | 2009 |
| SREBPs: sterol-regulated transcription factors PJ Espenshade Journal of cell science 119 (6), 973-976, 2006 | 245 | 2006 |
| Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans YC Chang, CM Bien, H Lee, PJ Espenshade, KJ Kwon‐Chung Molecular microbiology 64 (3), 614-629, 2007 | 234 | 2007 |
| Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p. P Espenshade, RE Gimeno, E Holzmacher, P Teung, CA Kaiser The Journal of cell biology 131 (2), 311-324, 1995 | 231 | 1995 |
| Hierarchical modularity and the evolution of genetic interactomes across species CJ Ryan, A Roguev, K Patrick, J Xu, H Jahari, Z Tong, P Beltrao, M Shales, ... Molecular cell 46 (5), 691-704, 2012 | 230 | 2012 |
| Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins PJ Espenshade, D Cheng, JL Goldstein, MS Brown Journal of Biological Chemistry 274 (32), 22795-22804, 1999 | 223 | 1999 |
| LST1 Is a SEC24 Homologue Used for Selective Export of the Plasma Membrane ATPase from the Endoplasmic Reticulum KJ Roberg, M Crotwell, P Espenshade, R Gimeno, CA Kaiser The Journal of cell biology 145 (4), 659-672, 1999 | 217 | 1999 |
| Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast BL Todd, EV Stewart, JS Burg, AL Hughes, PJ Espenshade Molecular and cellular biology, 2006 | 208 | 2006 |
| Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER PJ Espenshade, WP Li, D Yabe Proceedings of the National Academy of Sciences 99 (18), 11694-11699, 2002 | 197 | 2002 |
| COPII subunit interactions in the assembly of the vesicle coat DA Shaywitz, PJ Espenshade, RE Gimeno, CA Kaiser Journal of Biological Chemistry 272 (41), 25413-25416, 1997 | 191 | 1997 |
| Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis CM Bien, PJ Espenshade Eukaryotic cell 9 (3), 352-359, 2010 | 175 | 2010 |
