Randal Halfmann
Title
Cited by
Cited by
Year
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins
S Alberti, R Halfmann, O King, A Kapila, S Lindquist
Cell 137 (1), 146-158, 2009
8042009
Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation
X Cai, J Chen, H Xu, S Liu, QX Jiang, R Halfmann, ZJ Chen
Cell 156 (6), 1207-1222, 2014
3752014
Prions are a common mechanism for phenotypic inheritance in wild yeasts
R Halfmann, DF Jarosz, SK Jones, A Chang, AK Lancaster, S Lindquist
Nature 482 (7385), 363-368, 2012
3572012
Epigenetics in the extreme: prions and the inheritance of environmentally acquired traits
R Halfmann, S Lindquist
Science 330 (6004), 629-632, 2010
2312010
Prions, protein homeostasis, and phenotypic diversity
R Halfmann, S Alberti, S Lindquist
Trends in cell biology 20 (3), 125-133, 2010
1602010
Chaperone-dependent amyloid assembly protects cells from prion toxicity
PM Douglas, S Treusch, HY Ren, R Halfmann, ML Duennwald, ...
Proceedings of the National Academy of Sciences 105 (20), 7206-7211, 2008
1522008
Screening for amyloid aggregation by semi-denaturing detergent-agarose gel electrophoresis
R Halfmann, S Lindquist
JoVE (Journal of Visualized Experiments), e838, 2008
1512008
Heritable remodeling of yeast multicellularity by an environmentally responsive prion
DL Holmes, AK Lancaster, S Lindquist, R Halfmann
Cell 153 (1), 153-165, 2013
1432013
Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins
R Halfmann, S Alberti, R Krishnan, N Lyle, CW O'Donnell, OD King, ...
Molecular cell 43 (1), 72-84, 2011
1432011
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells
G Wang, X Wang, H Yu, S Wei, N Williams, DL Holmes, R Halfmann, ...
Nature chemical biology 9 (2), 84-89, 2013
892013
Prion formation by a yeast GLFG nucleoporin
R Halfmann, JR Wright, S Alberti, S Lindquist, M Rexach
Prion 6 (4), 391-399, 2012
582012
Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeast
S Alberti, R Halfmann, S Lindquist
Methods in enzymology 470, 709-734, 2010
572010
A method for probing the mutational landscape of amyloid structure
CW O'Donnell, J Waldispühl, M Lis, R Halfmann, S Devadas, S Lindquist, ...
Bioinformatics 27 (13), i34-i42, 2011
552011
Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior
T Khan, TS Kandola, J Wu, S Venkatesan, E Ketter, JJ Lange, AR Gama, ...
Molecular cell 71 (1), 155-168. e7, 2018
282018
A glass menagerie of low complexity sequences.
R Halfmann
Current Opinion in Structural Biology 38, 9-16, 2016
212016
A self-perpetuating repressive state of a viral replication protein blocks superinfection by the same virus
XF Zhang, R Sun, Q Guo, S Zhang, T Meulia, R Halfmann, D Li, F Qu
PLoS Pathogens 13 (3), e1006253, 2017
202017
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation
MJ Holliday, A Witt, AR Gama, BT Walters, CP Arthur, R Halfmann, ...
Nature communications 10 (1), 1-17, 2019
92019
Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure‐guided surface engineering
DW Close, CD Paul, PS Langan, MCJ Wilce, DAK Traore, R Halfmann, ...
Proteins: Structure, Function, and Bioinformatics 83 (7), 1225-1237, 2015
62015
Quinary structure kinetically controls protein function and dysfunction
T Khan, TS Kandola, J Wu, E Ketter, S Venkatesan, JJ Lange, AR Gama, ...
BioRxiv, 205690, 2017
22017
TGP, an extremely stable, non-aggregating fluorescent protein created by structure-guided surface engineering
DW Close, C Don Paul, PS Langan, MC Wilce, DA Traore, R Halfmann
Proteins: Structure, Function, and Bioinformatics, 2014
22014
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Articles 1–20