Pavlo Lutsik
Pavlo Lutsik
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Comprehensive analysis of DNA methylation data with RnBeads
Y Assenov, F Müller, P Lutsik, J Walter, T Lengauer, C Bock
Nature methods 11 (11), 1138-1140, 2014
Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human
S Tierling, NY Souren, J Gries, C LoPorto, M Groth, P Lutsik, H Neitzel, ...
Journal of medical genetics 47 (6), 371-376, 2010
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
P Lutsik, L Feuerbach, J Arand, T Lengauer, J Walter, C Bock
Nucleic acids research 39 (suppl_2), W551-W556, 2011
Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles
NYP Souren, P Lutsik, G Gasparoni, S Tierling, J Gries, ...
Genome biology 14 (5), R44, 2013
Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories
C Gerhauser, F Favero, T Risch, R Simon, L Feuerbach, Y Assenov, ...
Cancer Cell 34 (6), 996-1011. e8, 2018
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex
G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus, S Sordon, J Vlcek, ...
Epigenetics & chromatin 11 (1), 41, 2018
MeDeCom: discovery and quantification of latent components of heterogeneous methylomes
P Lutsik, M Slawski, G Gasparoni, N Vedeneev, M Hein, J Walter
Genome biology 18 (1), 1-20, 2017
RnBeads 2.0: comprehensive analysis of DNA methylation data
F Müller, M Scherer, Y Assenov, P Lutsik, J Walter, T Lengauer, C Bock
Genome biology 20 (1), 1-12, 2019
Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands
F Haller, M Bieg, R Will, C Körner, D Weichenhan, A Bott, N Ishaque, ...
Nature communications 10 (1), 1-13, 2019
Epigenome data release: a participant-centered approach to privacy protection
SOM Dyke, WA Cheung, Y Joly, O Ammerpohl, P Lutsik, MA Rothstein, ...
Genome biology 16 (1), 1-12, 2015
Matrix factorization with binary components
M Slawski, M Hein, P Lutsik
Advances in Neural Information Processing Systems, 3210-3218, 2013
Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology
J Gries, D Schumacher, J Arand, P Lutsik, MR Markelova, I Fichtner, ...
Epigenetics 8 (7), 765-771, 2013
BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives
D Becker, P Lutsik, P Ebert, C Bock, T Lengauer, J Walter
Nucleic acids research 42 (W1), W501-W507, 2014
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis
NY Souren, LA Gerdes, P Lutsik, G Gasparoni, E Beltrán, A Salhab, ...
Nature communications 10 (1), 1-12, 2019
Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma
B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ...
Hepatology 69 (5), 2091-2106, 2019
Mitochondrial DNA variation and heteroplasmy in monozygotic twins clinically discordant for multiple sclerosis
NYP Souren, LA Gerdes, T Kümpfel, P Lutsik, T Klopstock, R Hohlfeld, ...
Human mutation 37 (8), 765-775, 2016
Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software
C Decamps, F Privé, R Bacher, D Jost, A Waguet, EA Houseman, E Lurie, ...
BMC bioinformatics 21 (1), 1-15, 2020
Identification and analysis of methylation call differences between bisulfite microarray and bisulfite sequencing data with statistical learning techniques
M Döring, G Gasparoni, J Gries, K Nordström, P Lutsik, J Walter, N Pfeifer
BMC bioinformatics 16 (S3), A7, 2015
Neuronal ensemble-specific DNA methylation strengthens engram stability
KG Karaca, J Kupke, DVC Brito, B Zeuch, C Thome, D Weichenhan, ...
Nature communications 11 (1), 1-13, 2020
From basic knowledge to effective therapies
DB Lipka, P Lutsik, C Plass
Cancer cell 34 (6), 871-873, 2018
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