Kai Hilpert
Kai Hilpert
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Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
I Wiegand, K Hilpert, REW Hancock
Nature protocols 3 (2), 163-175, 2008
Alternatives to antibiotics—a pipeline portfolio review
L Czaplewski, R Bax, M Clokie, M Dawson, H Fairhead, VA Fischetti, ...
The Lancet infectious diseases 16 (2), 239-251, 2016
The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides
G Gao, D Lange, K Hilpert, J Kindrachuk, Y Zou, JTJ Cheng, ...
Biomaterials 32 (16), 3899-3909, 2011
High-throughput generation of small antibacterial peptides with improved activity
K Hilpert, R Volkmer-Engert, T Walter, REW Hancock
Nature biotechnology 23 (8), 1008-1012, 2005
Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs
A Cherkasov, K Hilpert, H Jenssen, CD Fjell, M Waldbrook, SC Mullaly, ...
ACS chemical biology 4 (1), 65-74, 2009
Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion
K Hilpert, DFH Winkler, REW Hancock
Nature protocols 2 (6), 1333-1349, 2007
Identification of novel antibacterial peptides by chemoinformatics and machine learning
CD Fjell, H Jenssen, K Hilpert, WA Cheung, N Panté, REW Hancock, ...
Journal of medicinal chemistry 52 (7), 2006-2015, 2009
Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides
S Ruden, K Hilpert, M Berditsch, P Wadhwani, AS Ulrich
Antimicrobial agents and chemotherapy 53 (8), 3538-3540, 2009
Screening and characterization of surface-tethered cationic peptides for antimicrobial activity
K Hilpert, M Elliott, H Jenssen, J Kindrachuk, CD Fjell, J Körner, ...
Chemistry & biology 16 (1), 58-69, 2009
Sequence requirements and an optimization strategy for short antimicrobial peptides
K Hilpert, MR Elliott, R Volkmer-Engert, P Henklein, O Donini, Q Zhou, ...
Chemistry & biology 13 (10), 1101-1107, 2006
Structural studies of a peptide with immune modulating and direct antimicrobial activity
M Wieczorek, H Jenssen, J Kindrachuk, WRP Scott, M Elliott, K Hilpert, ...
Chemistry & biology 17 (9), 970-980, 2010
The dolphin proline-rich antimicrobial peptide Tur1A inhibits protein synthesis by targeting the bacterial ribosome
M Mardirossian, N Pérébaskine, M Benincasa, S Gambato, S Hofmann, ...
Cell chemical biology 25 (5), 530-539. e7, 2018
Easy strategy to protect antimicrobial peptides from fast degradation in serum
D Knappe, P Henklein, R Hoffmann, K Hilpert
Antimicrobial agents and chemotherapy 54 (9), 4003-4005, 2010
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins
J Stewart-Ornstein, AP Hitchcock, D Hernández Cruz, P Henklein, ...
The Journal of Physical Chemistry B 111 (26), 7691-7699, 2007
Targeting Mycobacterium tuberculosis and other microbial pathogens using improved synthetic antibacterial peptides
S Ramón-García, R Mikut, C Ng, S Ruden, R Volkmer, M Reischl, ...
Antimicrobial agents and chemotherapy 57 (5), 2295-2303, 2013
Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology
K Hilpert, REW Hancock
Nature Protocols 2 (7), 1652-1660, 2007
Short cationic antimicrobial peptides interact with ATP
K Hilpert, B McLeod, J Yu, MR Elliott, M Rautenbach, S Ruden, J Bürck, ...
Antimicrobial agents and chemotherapy 54 (10), 4480-4483, 2010
Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose
K Hilpert, G Hansen, H Wessner, G Küttner, K Welfle, M Seifert, W Höhne
Protein engineering 14 (10), 803-806, 2001
Evaluating Different Descriptors for Model Design of Antimicrobial Peptides with Enhanced Activity Toward P. aeruginosa
H Jenssen, T Lejon, K Hilpert, CD Fjell, A Cherkasov, REW Hancock
Chemical biology & drug design 70 (2), 134-142, 2007
Screening for Antifungal Peptides and Their Modes of Action in Aspergillus nidulans
D Mania, K Hilpert, S Ruden, R Fischer, N Takeshita
Applied and Environmental Microbiology 76 (21), 7102-7108, 2010
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