Molecular Basis of TRPA1 Regulation in Nociceptive Neurons. A Review A KÁDKOVÁ, V SYNYTSYA, J KRUSEK, L ZÍMOVÁ, V VLACHOVÁ Physiol. Res 66, 425-439, 2017 | 66 | 2017 |
C-terminal acidic cluster is involved in Ca2+-induced regulation of human transient receptor potential ankyrin 1 channel L Sura, V Zíma, L Marsakova, A Hynkova, I Barvík, V Vlachova Journal of Biological Chemistry 287 (22), 18067-18077, 2012 | 65 | 2012 |
The C-terminal basic residues contribute to the chemical-and voltage-dependent activation of TRPA1 A Samad, L Sura, J Benedikt, R Ettrich, B Minofar, J Teisinger, V Vlachova Biochemical Journal 433 (1), 197-204, 2011 | 60 | 2011 |
Human and mouse TRPA1 are heat and cold sensors differentially tuned by voltage V Sinica, L Zimova, K Barvikova, L Macikova, I Barvik, V Vlachova Cells 9 (1), 57, 2019 | 36 | 2019 |
Intracellular cavity of sensor domain controls allosteric gating of TRPA1 channel L Zimova, V Sinica, A Kadkova, L Vyklicka, V Zima, I Barvik, V Vlachova Science signaling 11 (514), eaan8621, 2018 | 33 | 2018 |
Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state V Zíma, K Witschas, A Hynkova, L Zímová, I Barvík, V Vlachova Neuropharmacology 93, 294-307, 2015 | 29 | 2015 |
Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful? S Boukalova, F Touska, L Marsakova, A Hynkova, L Sura, S Chvojka, ... Physiological research 63, S205, 2014 | 29 | 2014 |
The first extracellular linker is important for several aspects of the gating mechanism of human TRPA1 channel L Marsakova, I Barvik, V Zima, L Zimova, V Vlachova Frontiers in molecular neuroscience 10, 16, 2017 | 27 | 2017 |
Proximal C-terminus serves as a signaling hub for TRPA1 channel regulation via its interacting molecules and supramolecular complexes L Zimova, K Barvikova, L Macikova, L Vyklicka, V Sinica, I Barvik, ... Frontiers in physiology 11, 189, 2020 | 18 | 2020 |
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function L Zhang, C Simonsen, L Zimova, K Wang, L Moparthi, R Gaudet, M Ekoff, ... Nature Communications 13 (1), 7483, 2022 | 10 | 2022 |
Cellular context determines primary characteristics of human TRPC5 as a cold‐activated channel A Ptakova, M Mitro, L Zimova, V Vlachova Journal of Cellular Physiology 237 (9), 3614-3626, 2022 | 4 | 2022 |
Activity dependent inhibition of TRPC1/4/5 channels by duloxetine involves voltage sensor-like domain L Zimova, A Ptakova, M Mitro, J Krusek, V Vlachova Biomedicine & Pharmacotherapy 152, 113262, 2022 | 3 | 2022 |
Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel K Barvikova, I Barvik, V Sinica, L Zimova, V Vlachova International Journal of Molecular Sciences 21 (21), 7995, 2020 | 3 | 2020 |
Identification of a putative region critical for cold sensitivity of TRPA1 L Zimova, V Sinica, K Barvikova, V Vlachova EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 48, S167-S167, 2019 | 1 | 2019 |
Potent direct inhibition of TRPC5 by an antidepressant and analgesic drug duloxetine L Zimova, A Ptakova, M Mitro, L Loudova, V Vlachova EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 50 (SUPPL 1), 96-96, 2021 | | 2021 |
The role of charged residues in the activation and modulation of the TRPA1 ion channel L Zímová Univerzita Karlova, Matematicko-fyzikální fakulta, 2015 | | 2015 |
The S4-S5 linker of transient receptor potential ankyrin 1 as a precise stimuli integrator L Zimova, V Synytsya, K Witschas, A Hynkova, V Zima, I Barvik, ... 10th European Biophysical Societies Association (EBSA) European Biophysics …, 2015 | | 2015 |
S4-S5 Linker is Involved in Voltage-Dependent Gating of Human Transient Receptor Potential Ankyrin 1 Channel K Witschas, L Sura, V Zima, A Hynkova, I Barvik, V Vlachova Biophysical Journal 104 (2), 453a-454a, 2013 | | 2013 |
Clues to understanding the voltage regulation of TRPA1 V Zima, L Sura, I Barvik, V Vlachova EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 40, 174-174, 2011 | | 2011 |