Qian Yin
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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
A Lu, VG Magupalli, J Ruan, Q Yin, MK Atianand, MR Vos, GF Schröder, ...
Cell 156 (6), 1193-1206, 2014
Hydrolysis of 2′ 3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
L Li, Q Yin, P Kuss, Z Maliga, JL Millán, H Wu, TJ Mitchison
Nature chemical biology 10 (12), 1043-1048, 2014
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
L Zhang, S Chen, J Ruan, J Wu, AB Tong, Q Yin, Y Li, L David, A Lu, ...
Science 350 (6259), 404-409, 2015
E2 interaction and dimerization in the crystal structure of TRAF6
Q Yin, SC Lin, B Lamothe, M Lu, YC Lo, G Hura, L Zheng, RL Rich, ...
Nature structural & molecular biology 16 (6), 658-666, 2009
The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations
L Wang, JK Yang, V Kabaleeswaran, AJ Rice, AC Cruz, AY Park, Q Yin, ...
Nature structural & molecular biology 17 (11), 1324-1329, 2010
Cyclic di-GMP sensing via the innate immune signaling protein STING
Q Yin, Y Tian, V Kabaleeswaran, X Jiang, D Tu, MJ Eck, ZJ Chen, H Wu
Molecular cell 46 (6), 735-745, 2012
Structural studies of NF-κB signaling
C Zheng, Q Yin, H Wu
Cell research 21 (1), 183-195, 2011
AIM2 inflammasome activation and regulation: a structural perspective
B Wang, Q Yin
Journal of structural biology 200 (3), 279-282, 2017
Anticancer flavonoids are mouse-selective STING agonists
S Kim, L Li, Z Maliga, Q Yin, H Wu, TJ Mitchison
ACS chemical biology 8 (7), 1396-1401, 2013
Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme
TT Lu, M Onizawa, GE Hammer, EE Turer, Q Yin, E Damko, A Agelidis, ...
Immunity 38 (5), 896-905, 2013
A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP Dynamic and cooperative regulation of XIAP by Smac/Diablo
Z Gao, Y Tian, J Wang, Q Yin, H Wu, YM Li, X Jiang
Journal of Biological Chemistry 282 (42), 30718-30727, 2007
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism
A Lu, Y Li, FI Schmidt, Q Yin, S Chen, T Fu, AB Tong, HL Ploegh, Y Mao, ...
Nature Structural and Molecular Biology 23 (5), 416-425, 2016
Structural basis of signal transduction in the TNF receptor superfamily
J Li, Q Yin, H Wu
Advances in immunology 119, 135-153, 2013
Structural Biology of Innate Immunity
Q Yin, TM Fu, J Li, H Wu
Annual Review of Immunology 33 (1), 2015
Structural basis for the lack of E2 interaction in the RING domain of TRAF2
Q Yin, B Lamothe, BG Darnay, H Wu
Biochemistry 48 (44), 10558-10567, 2009
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine
Q Yin, HH Park, JY Chung, SC Lin, YC Lo, LS da Graca, X Jiang, H Wu
Molecular cell 22 (2), 259-268, 2006
Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation
Q Yin, DP Sester, Y Tian, YS Hsiao, A Lu, JA Cridland, V Sagulenko, ...
Cell reports 4 (2), 327-339, 2013
Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2
A Lu, Y Li, Q Yin, J Ruan, X Yu, E Egelman, H Wu
Cell discovery 1 (1), 1-14, 2015
Molecular basis for the unique specificity of TRAF6
JY Chung, M Lu, Q Yin, SC Lin, H Wu
TNF Receptor Associated Factors (TRAFs), 122-130, 2007
Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex
Y Tian, DK Simanshu, M Ascano, R Diaz-Avalos, AY Park, SA Juranek, ...
Nature structural & molecular biology 18 (6), 658-664, 2011
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