Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007 | 2303 | 2007 |
A haplotype map of the human genome D Altshuler Nature 437, 1299-1320, 2005 | 1204 | 2005 |
Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350 Y Ohnishi, J Ishikawa, H Hara, H Suzuki, M Ikenoya, H Ikeda, ... Journal of bacteriology 190 (11), 4050-4060, 2008 | 689 | 2008 |
A new pathway for polyketide synthesis in microorganisms N Funa, Y Ohnishi, I Fujii, M Shibuya, Y Ebizuka, S Horinouchi Nature 400 (6747), 897-899, 1999 | 412 | 1999 |
Production of Plant-Specific Flavanones by Escherichia coli Containing an Artificial Gene Cluster EI Hwang, M Kaneko, Y Ohnishi, S Horinouchi Applied and environmental microbiology 69 (5), 2699-2706, 2003 | 316 | 2003 |
The A‐factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A‐factor receptor Y Ohnishi, S Kameyama, H Onaka, S Horinouchi Molecular microbiology 34 (1), 102-111, 1999 | 311 | 1999 |
AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus Y Ohnishi, H Yamazaki, JY Kato, A Tomono, S Horinouchi Bioscience, biotechnology, and biochemistry 69 (3), 431-439, 2005 | 299 | 2005 |
Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster I Miyahisa, M Kaneko, N Funa, H Kawasaki, H Kojima, Y Ohnishi, ... Applied microbiology and biotechnology 68, 498-504, 2005 | 229 | 2005 |
Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces J Kato, N Funa, H Watanabe, Y Ohnishi, S Horinouchi Proceedings of the National Academy of Sciences 104 (7), 2378-2383, 2007 | 221 | 2007 |
Combinatorial biosynthesis of flavones and flavonols in Escherichia coli I Miyahisa, N Funa, Y Ohnishi, S Martens, T Moriguchi, S Horinouchi Applied microbiology and biotechnology 71, 53-58, 2006 | 198 | 2006 |
Determinants of protein thermostability observed in the 1.9-. ANG. crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus CA Kelly, M Nishiyama, Y Ohnishi, T Beppu, JJ Birktoft Biochemistry 32 (15), 3913-3922, 1993 | 179 | 1993 |
An A-Factor-Dependent Extracytoplasmic Function Sigma Factor (ςAdsA) That Is Essential for Morphological Development in Streptomyces griseus H Yamazaki, Y Ohnishi, S Horinouchi Journal of bacteriology 182 (16), 4596-4605, 2000 | 133 | 2000 |
AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs A Tanaka, Y Takano, Y Ohnishi, S Horinouchi Journal of molecular biology 369 (2), 322-333, 2007 | 121 | 2007 |
Biosynthesis of Hexahydroxyperylenequinone Melanin via Oxidative Aryl Coupling by Cytochrome P-450 in Streptomyces griseus N Funa, M Funabashi, Y Ohnishi, S Horinouchi Journal of bacteriology 187 (23), 8149-8155, 2005 | 118 | 2005 |
DNA‐binding specificity of AdpA, a transcriptional activator in the A‐factor regulatory cascade in Streptomyces griseus H Yamazaki, A Tomono, Y Ohnishi, S Horinouchi Molecular microbiology 53 (2), 555-572, 2004 | 118 | 2004 |
Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and … A Higo, H Hara, S Horinouchi, Y Ohnishi DNA research 19 (3), 259-274, 2012 | 117 | 2012 |
Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus N Funa, Y Ohnishi, Y Ebizuka, S Horinouchi Journal of Biological Chemistry 277 (7), 4628-4635, 2002 | 117 | 2002 |
Crystal structure of a γ-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3 (2) R Natsume, Y Ohnishi, T Senda, S Horinouchi Journal of molecular biology 336 (2), 409-419, 2004 | 114 | 2004 |
Cinnamate:Coenzyme A Ligase from the Filamentous Bacterium Streptomyces coelicolor A3(2) M Kaneko, Y Ohnishi, S Horinouchi Journal of bacteriology 185 (1), 20-27, 2003 | 108 | 2003 |
Heterologous production of flavanones in Escherichia coli: potential for combinatorial biosynthesis of flavonoids in bacteria M Kaneko, EI Hwang, Y Ohnishi, S Horinouchi Journal of Industrial Microbiology and Biotechnology 30, 456-461, 2003 | 107 | 2003 |