Rama Khokha
Rama Khokha
Professor, University of Toronto, Ontario cancer institute
Verified email at uhnres.utoronto.ca
Cited by
Cited by
Regulation of cancer cell migration and bone metastasis by RANKL
DH Jones, T Nakashima, OH Sanchez, I Kozieradzki, SV Komarova, ...
Nature 440 (7084), 692-696, 2006
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
JE Fata, YY Kong, J Li, T Sasaki, J Irie-Sasaki, RA Moorehead, R Elliott, ...
Cell 103 (1), 41-50, 2000
Progesterone induces adult mammary stem cell expansion
PA Joshi, HW Jackson, AG Beristain, MA Di Grappa, PA Mote, CL Clarke, ...
Nature 465 (7299), 803-807, 2010
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ...
Cancer cell 27 (2), 211-222, 2015
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.
KJ Leco, R Khokha, N Pavloff, SP Hawkes, DR Edwards
Journal of Biological Chemistry 269 (12), 9352-9360, 1994
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells
R Khokha, P Waterhouse, S Yagel, PK Lala, CM Overall, G Norton, ...
Science 243 (4893), 947-950, 1989
Suppression of tumor growth and metastasis in Mgat5-deficient mice
M Granovsky, J Fata, J Pawling, WJ Muller, R Khokha, JW Dennis
Nature medicine 6 (3), 306-312, 2000
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ...
Nature 468 (7320), 98-102, 2010
Metalloproteinases and their natural inhibitors in inflammation and immunity
R Khokha, A Murthy, A Weiss
Nature Reviews Immunology 13 (9), 649-665, 2013
Tumor necrosis factor-α mediates cardiac remodeling and ventricular dysfunction after pressure overload state
M Sun, M Chen, F Dawood, U Zurawska, JY Li, T Parker, Z Kassiri, ...
Circulation 115 (11), 1398-1407, 2007
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
A Hakem, O Sanchez-Sweatman, A You-Ten, G Duncan, A Wakeham, ...
Genes & development 19 (17), 1974-1979, 2005
The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer
T Li, L Sun, N Miller, T Nicklee, J Woo, L Hulse-Smith, MS Tsao, R Khokha, ...
Cancer Epidemiology and Prevention Biomarkers 14 (2), 343-349, 2005
Steps in tumor metastasis: new concepts from intravital videomicroscopy
AF Chambers, IC MacDonald, EE Schmidt, S Koop, VL Morris, R Khokha, ...
Cancer and Metastasis Reviews 14 (4), 279-301, 1995
Molecular mechanisms of tumor invasion and metastasis: an integrated view
RA Cairns, R Khokha, RP Hill
Current molecular medicine 3 (7), 659-671, 2003
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
KJ Leco, P Waterhouse, OH Sanchez, KLM Gowing, AR Poole, ...
The Journal of clinical investigation 108 (6), 817-829, 2001
Abnormal TNF activity in Timp3−/− mice leads to chronic hepatic inflammation and failure of liver regeneration
FF Mohammed, DS Smookler, SEM Taylor, B Fingleton, Z Kassiri, ...
Nature genetics 36 (9), 969-977, 2004
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution
S Schenk, E Hintermann, M Bilban, N Koshikawa, C Hojilla, R Khokha, ...
The Journal of cell biology 161 (1), 197-209, 2003
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
DR McIlwain, PA Lang, T Maretzky, K Hamada, K Ohishi, SK Maney, ...
Science 335 (6065), 229-232, 2012
Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development
CV Hojilla, FF Mohammed, R Khokha
British journal of cancer 89 (10), 1817-1821, 2003
Growth factors and stromal matrix proteins associated with mammographic densities
YP Guo, LJ Martin, W Hanna, D Banerjee, N Miller, E Fishell, R Khokha, ...
Cancer Epidemiology and Prevention Biomarkers 10 (3), 243-248, 2001
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