The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA A Deep, Y Gu, YQ Gao, KM Ego, MA Herzik, H Zhou, KD Corbett Molecular Cell 82 (21), 4145-4159. e7, 2022 | 49 | 2022 |
Architecture and self-assembly of the jumbo bacteriophage nuclear shell TG Laughlin*, A Deep*, AM Prichard, C Seitz, Y Gu, E Enustun, S Suslov, ... Nature 608 (7922), 429-435, 2022 | 47 | 2022 |
Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle … A Deep, P Tiwari, S Agarwal, S Kaundal, S Kidwai, R Singh, KG Thakur Nucleic acids research 46 (21), 11639-11655, 2018 | 41 | 2018 |
System-wide analysis unravels the differential regulation and in vivo essentiality of virulence-associated proteins B and C toxin-antitoxin systems of Mycobacterium tuberculosis S Agarwal, P Tiwari, A Deep, S Kidwai, S Gupta, KG Thakur, R Singh The Journal of Infectious Diseases 217 (11), 1809-1820, 2018 | 37 | 2018 |
VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response S Agarwal, A Sharma, R Bouzeyen, A Deep, H Sharma, ... Science advances 6 (23), eaba6944, 2020 | 34 | 2020 |
Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner S Mawatwal, A Behura, A Ghosh, S Kidwai, A Mishra, A Deep, S Agarwal, ... Biochimica Et Biophysica Acta (BBA)-General Subjects 1861 (12), 3190-3200, 2017 | 33 | 2017 |
Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin–antitoxin assembly A Deep, S Kaundal, S Agarwal, R Singh, KG Thakur The FEBS Journal 284 (23), 4066-4082, 2017 | 21 | 2017 |
Molecular and biochemical characterization of YeeF/YezG, a polymorphic toxin-immunity protein pair from Bacillus subtilis S Kaundal, A Deep, G Kaur, KG Thakur Frontiers in Microbiology 11, 512166, 2020 | 17 | 2020 |
Sequential membrane-and protein-bound organelles compartmentalize genomes during phage infection EG Armbruster, J Lee, J Hutchings, AR VanderWal, E Enustun, BA Adler, ... bioRxiv, 2023 | 7 | 2023 |
BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses J Houston, M Ohta, JS Gómez-Cavazos, A Deep, KD Corbett, K Oegema, ... Current Biology 33 (11), 2291-2299. e10, 2023 | 6 | 2023 |
Development 68Ga trastuzumab Fab and bioevaluation by PET imaging in HER2/neu expressing breast cancer patients Y Rathore, J Shukla, I Laroiya, A Deep, T Lakhanpal, R Kumar, H Singh, ... Nuclear Medicine Communications 43 (4), 458-467, 2022 | 6 | 2022 |
Identification of the bacteriophage nucleus protein interaction network E Enustun, A Deep, Y Gu, KT Nguyen, V Chaikeeratisak, E Armbruster, ... Nature Structural & Molecular Biology 30, 1653–1662, 2023 | 4 | 2023 |
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection E Enustun, EG Armbruster, J Lee, S Zhang, BA Yee, K Malukhina, Y Gu, ... Nucleic Acids Research 52 (8), 4440-4455, 2024 | 3 | 2024 |
Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited A Deep, L Singh, J Kaur, M Velusamy, P Bhardwaj, R Singh, KG Thakur Structure 31 (7), 780-789. e4, 2023 | 3 | 2023 |
Loop extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex B Pradhan*, A Deep*, J Koenig, M Baaske, K Corbett, E Kim bioRxiv, 2024.02. 17.580791, 2024 | 1 | 2024 |
Phosphorylation regulates tau’s phase separation behavior and interactions with chromatin LS Abasi, N Elathram, M Movva, A Deep, KD Corbett, GT Debelouchina Communications Biology 7 (1), 251, 2024 | | 2024 |
Phospho-KNL-1 recognition by a TPR domain targets the BUB-1/BUB-3 complex to C. elegans kinetochores J Houston, C Vissotsky, A Deep, H Hakozaki, E Crews, K Oegema, ... bioRxiv, 2024.02. 09.579536, 2024 | | 2024 |
Architecture and infection-sensing mechanism of the bacterial PARIS defense system A Deep, Q Liang, E Enustun, J Pogliano, KD Corbett bioRxiv, 2024.01. 02.573835, 2024 | | 2024 |
Bacterial Shedu immune nucleases share a common enzymatic core regulated by diverse sensor domains Y Gu, H Li, A Deep, E Enustun, D Zhang, KD Corbett bioRxiv, 2023 | | 2023 |
28P Development 68Ga trastuzumab Fab and bioevaluation by PET imaging in HER2/neu-expressing breast cancer patients Y Rathore, J Shukla, T Lakhanpal, I Laroiya, A Deep, R Kumar, H Singh, ... Annals of Oncology 33, S1441, 2022 | | 2022 |